Results 111 to 120 of about 143,576 (340)

VesselMorph: Domain-Generalized Retinal Vessel Segmentation via Shape-Aware Representation [PDF]

open access: green, 2023
Dewei Hu   +5 more
openalex   +1 more source

Potential neuroprotective and therapeutic agents and their mechanisms for irradiation‐induced brain injury

open access: yesIbrain, EarlyView.
In this review, agents such baicalein, troxerutin, epigallocatechin gallate, quercetin, melatonin, valproic acid, lithium, neurosteroid progesterone, as well as minocycline have been implicated as neuroprotective agents for irradiation‐induced neurological deficits. Also, agents such as glucocorticoids, methylphenidate, vitamin E, bisdemethoxycurcumin,
Seidu A. Richard   +2 more
wiley   +1 more source

Optic nerve aplasia: A case series

open access: yesIndian Journal of Ophthalmology, 2018
Optic nerve aplasia (ONA) is a congenital optic nerve anomaly characterized by the absence of optic nerve head, retinal blood vessels, retinal ganglion cells, and optic nerve fibers in a malformed eye.
K Samyukta Sadasivan   +3 more
doaj   +1 more source

Hypertensive retinopathy in pre‐eclampsia and its association with disease severity and neonatal outcomes: A retrospective cohort study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Introduction Pre‐eclampsia (PE) involves systemic endothelial dysfunction and microvascular injury, yet routine obstetric care lacks noninvasive readouts of maternal microvascular health. We evaluated whether hypertensive retinopathy (HR) detected during pregnancy is associated with maternal disease severity and adverse neonatal outcomes ...
Gabriele Saccone   +6 more
wiley   +1 more source

Detection of Hard Exudates in Retinal Fundus Images using Deep Learning

open access: yes, 2018
Diabetic Retinopathy (DR) is a retinal disorder that affects the people having diabetes mellitus for a long time (20 years). DR is one of the main reasons for the preventable blindness all over the world. If not detected early the patient may progress to
Benzamin, Avula, Chakraborty, Chandan
core   +1 more source

A deep convolutional neural network-based novel class balancing for imbalance data segmentation

open access: yesScientific Reports
Retinal fundus images provide valuable insights into the human eye’s interior structure and crucial features, such as blood vessels, optic disk, macula, and fovea.
Atifa Kalsoom   +5 more
doaj   +1 more source

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

open access: yesInterdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui   +12 more
wiley   +1 more source

l-Citrulline dilates rat retinal arterioles via nitric oxide- and prostaglandin-dependent pathways in vivo

open access: yesJournal of Pharmacological Sciences, 2015
l-Citrulline is an effective precursor of l-arginine produced by the l-citrulline/l-arginine cycle, and it exerts beneficial effects on the cardiovascular system by supporting enhanced nitric oxide (NO) production.
Asami Mori   +5 more
doaj   +1 more source

Ginsenoside Rb1 Targets the HRD1‐STING Axis to Mitigate Cholesterol‐Induced VSMC Senescence

open access: yesJournal of Clinical Laboratory Analysis, EarlyView.
Schematic representation of the proposed mechanism of action for Ginsenoside Rb1. Suppression of HRD1 expression in VSMCs cholesterol stimulation, leading to ER stress (BiP/XBP1s upregulation), STING pathway activation, ROS accumulation (including mitochondrial ROS), and ultimately, VSMC senescence.
Haiming Niu   +5 more
wiley   +1 more source

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