Results 101 to 110 of about 145,462 (345)
Exact model comparisons in the plausibility framework [PDF]
, 2019 Plausibility is a formalization of exact tests for parametric models and generalizes procedures such as Fisher's exact test. The resulting tests are based on cumulative probabilities of the probability density function and evaluate consistency with a parametric family while providing exact control of the $\alpha$ level for finite sample size.
arxiv +1 more source
History and Genetics of Retinoblastoma [PDF]
, 2019 The history of retinoblastoma (RB) goes back to 1597 when Pieter Pawius of Amsterdam described a tumor that resembled retinoblastoma. “Fungus haematodes” was the first term used to describe retinoblastoma.
Albahlal, Abdullah +4 more
core +2 more sources
Cancer Communications, EarlyView.Abstract Background Bireociclib (XZP‐3287) is a novel selective cyclin‐dependent kinase 4 and 6 (CDK4/6) inhibitor, with a favorable safety profile demonstrated in preclinical and phase I studies. BRIGHT‐1 aimed to further explore the efficacy and safety of bireociclib monotherapy in patients with locally advanced, recurrent or metastatic, hormone ...
Jiayu Wang +18 more
wiley +1 more source
Classification and staging of retinoblastoma
Community Eye Health Journal, 2018 Classifying and staging retinoblastoma is an essential first step when planning how to manage a child with the condition; it also gives important information about prognosis.
Ido Didi Fabian +2 more
doaj
Bone metastasis of retinoblastoma five years after primary treatment
American Journal of Ophthalmology Case Reports, 2020 Purpose: Histopathological, immunohistochemistry- and molecular pathology-based diagnostics to distinguish metastasis of retinoblastoma from subsequent primary malignancy in patients with heritable retinoblastoma.
Saskia C. Ting +7 more
doaj
Cell Death Discovery, 2022 Chemotherapy resistance of tumor cells causes failure in anti-tumor therapies. Recently, N-terminal regulator of chromatin condensation 1 methyltransferase (NRMT) is abnormally expressed in different cancers.
Zhongrui Li +5 more
doaj +1 more source
Molecular Network Control Through Boolean Canalization [PDF]
, 2015 Boolean networks are an important class of computational models for molecular interaction networks. Boolean canalization, a type of hierarchical clustering of the inputs of a Boolean function, has been extensively studied in the context of network ...
Dimitrova, Elena S., Murrugarra, David
core +3 more sources
Clinical Pharmacology &Therapeutics, EarlyView.In pediatric oncology, pharmacogenetic guidelines are underutilized and the potential impact of pre‐emptive pharmacogenetic screening remains largely unexplored despite this field's need for individualized approaches. While comprehensive pharmacogenetic guidelines are not yet available for all anticancer drugs, evidence‐based recommendations exist for ...
Emma C. Bernsen +12 more
wiley +1 more source
Retinoblastoma protein is the likely common effector for distinct anti-aging pathways [PDF]
arXiv, 2007 The multiple worlds of genetically manipulated laboratory organisms such as transgenic mice or worms with certain gene mutations are somewhat reminiscent of parallel worlds in quantum mechanics. So are various models of aging tested in such organisms.
arxiv
Secondary Malignancies in Adulthood and after Retinoblastoma Treatment in Childhood [PDF]
, 2019 Advances in retinoblastoma treatment in children nowadays and in the last decades lead to success and adulthood life without problems. Treatment modalities used in childhood to cure the retinoblastoma can affect health later.
Furdova, Alena, Sekac, Juraj
core +2 more sources