Results 111 to 120 of about 93,615 (295)

DIFFUSE INFILTRATING RETINOBLASTOMA [PDF]

, 1960
P. B. Schofield
openalex   +1 more source

CRISPR‐Cas9 screen reveals that inhibition of enhancer of zeste homolog 2 sensitizes malignant T cells to dimethyl‐fumarate‐induced cell death

The FEBS Journal, EarlyView.
A genome‐wide CRISPR‐Cas9 screen identified H3K27 methylation as a key regulator of T‐cell lymphoma sensitivity to dimethyl fumarate (DMF). Specifically, inhibition of enhancer of zeste homolog 2 (EZH2) enhanced DMF‐induced cell death in malignant T cells. These results provide functional evidence for the role of EZH2 in modulating drug sensitivity and
Jan P. Teubner, Deniz Tümen, Arne Kandulski, Philipp Heumann, Patricia Mester, Elisabeth Aschenbrenner, Kirstin Pollinger, Manuela Gunckel, Barbara Volz, Tobias Hein, Paul L. Beltzig, Luisa Tengler, Florian Voll, Marina Kreutz, Claudia Kunst, Jan P. Nicolay, Martina Müller, Karsten Gülow   +17 more
wiley   +1 more source

Genetics and management of retinoblastoma

Journal of Indian Association of Pediatric Surgeons, 2007
Retinoblastoma is the most common intraocular tumor in childhood. In majority of early stage retinoblastoma, the eyeballs as well as vision can be preserved with chemotherapy and local intraocular therapy with laser or photocoagulation.
Bakhshi Sameer, Bakhshi Radhika
doaj  

Retinoblastoma. Part 1. Clinical presentations and diagnostic tools [PDF]

РМЖ "Клиническая офтальмология", 2020
Retinoblastoma. Part 1. Clinical presentations and diagnostic tools S.V. Ivanova1, S.A. Kuleva1, N.N. Sadovnikova2, M.I. Komissarov2, M.N. Chistyakova2, A.V. Khokhlova1, N.A. Shchegoleva3 1N.N.
S.V. Ivanova, S.A. Kuleva, N.N. Sadovnikova, M.I. Komissarov, M.N. Chistyakova, A.V. Khokhlova, N.A. Shchegoleva   +6 more
doaj  

Tigecycline as a dual inhibitor of retinoblastoma and angiogenesis via inducing mitochondrial dysfunctions and oxidative damage

Scientific Reports, 2018
Retinoblastoma is the most common intraocular malignancy in children with poor prognosis. The progression of retinoblastoma is dependent on a robust angiogenic response.
Ying Xiong, Wei Liu, Qian Huang, Jierong Wang, Yanjun Wang, Huijuan Li, Xuedong Fu   +6 more
semanticscholar   +1 more source

Loss of MTAP expression is not an accurate surrogate for CDKN2A homozygous deletions in peritoneal mesothelioma

Histopathology, EarlyView.
MTAP immunohistochemistry (IHC) was evaluated as a diagnostic tool for peritoneal mesothelioma by comparing it with CDKN2A homozygous deletion (HD) detected by FISH. Results showed low concordance between MTAP IHC and CDKN2A HD, suggesting MTAP IHC is not reliable for predicting CDKN2A HD in peritoneal mesothelioma. Further studies are needed.
Andrea Quaranta, Andrea Marzullo, Francesco Fortarezza, Sonia Maniglio, Concetta Caporusso, Floriana Pentimone, Federica Pezzuto, Domenica Cavone, Teresa Lettini, Mario Magistro, Cecilia Salzillo, Luigi Vimercati, Paolo Graziano, Gabriella Serio, Antonio d'Amati   +14 more
wiley   +1 more source

Retinoblastoma in Adults: a Case Report and Literature Review

Journal of Ophthalmic & Vision Research, 2014
Purpose: To report a case of adult retinoblastoma with a wrong diagnosis of melanoma. Case report: Herein, we present an adult retinoblastoma case who was misdiagnosed as melanoma in fine-needle aspiration biopsy with intravitreal hemorrhage and later ...
Mehdi Sharifzadeh, Fariba Ghassemi, Fahimeh Asadi Amoli, Elham Rahmanikhah, Seid Zia Tabatabaie   +4 more
doaj   +1 more source

Retinoblastoma. Report on 19 patients treated with radio- therapy. [PDF]

, 1965
Mark Paterson, Alexander A. Charteris
openalex   +1 more source

Polo‐like kinases and UV‐induced skin carcinogenesis: What we know and what's next

Photochemistry and Photobiology, EarlyView.
The polo‐like kinase (PLK) family plays distinct and critical roles in the regulation of cell cycle progression, and its dysregulation has been implicated in various cancers. Ultraviolet (UV) radiation is a well‐established environmental factor in the development of skin cancer.
Tanya Jaiswal, Durdana Muntaqua, Gagan Chhabra, Nihal Ahmad   +3 more
wiley   +1 more source

Genetics of Retinoblastoma

Asia-Pacific Journal of Ophthalmology, 2016
Retinoblastoma is a malignant retinal tumor that affects young children. Mutations in the RB1 gene cause retinoblastoma. Mutations in both RB1 alleles within the precursor retinal cell are essential, with one mutation that may be germline or somatic and the second one that is always somatic. Identification of the RB1 germline status of a patient allows
Arun D. Singh, Meghan J Marino, Ashwin Mallipatna   +2 more
openaire   +2 more sources