Results 121 to 130 of about 57,195 (184)

MANAGEMENT OF RETINOBLASTOMA [PDF]

open access: yesAnnals of the New York Academy of Sciences, 1964
Robert M. Ellsworth, Algernon B. Reese
openaire   +5 more sources

Genetics of Retinoblastoma

open access: yesAsia-Pacific Journal of Ophthalmology, 2016
Retinoblastoma is a malignant retinal tumor that affects young children. Mutations in the RB1 gene cause retinoblastoma. Mutations in both RB1 alleles within the precursor retinal cell are essential, with one mutation that may be germline or somatic and the second one that is always somatic. Identification of the RB1 germline status of a patient allows
Arun D. Singh   +2 more
openaire   +2 more sources

Expression patterns of melanin‐related genes are linked to crypsis and conspicuousness in a pumpkin toadlet

open access: yesMolecular Ecology, EarlyView.
Abstract Colour signals play pivotal roles in different communication systems, and the evolution of these characters has been associated with behavioural ecology, integumentary production processes and perceptual mechanisms of the species involved. Here, we present the first insight into the molecular and histological basis of skin colour polymorphism ...
Juliane P. C. Monteiro   +7 more
wiley   +1 more source

The expression of tumour suppressors and proto-oncogenes in tissues susceptible to their hereditary cancers. [PDF]

open access: yes, 2015
BackgroundStudies of familial cancers have found that only a small subset of tissues are affected by inherited mutations in a given tumour suppressor gene (TSG) or proto-oncogene (POG), even though the mutation is present in all tissues.
Muir, Brian, Nunney, Leonard
core  

Optimised Ribosome Profiling Reveals New Insights Into Translational Regulation in Synchronised Chlamydomonas reinhardtii Cultures

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT Deep sequencing of ribosome footprints, also known as ribosome profiling (Ribo‐seq), enables the quantification of mRNA translation and a comprehensive view of the translatome landscape. Here, we report an optimised Ribo‐seq protocol and analysis pipeline for the model green alga, Chlamydomonas reinhardtiii (Chlamydomonas).
Yen‐Ling Lin   +4 more
wiley   +1 more source

Managing and treating intraocular retinoblastoma

open access: yesCommunity Eye Health Journal, 2018
In order to improve the survival rates of children with retinoblastoma, a collaborative and multidisciplinary approach is essential, as is a listening ear for parents who may struggle with the difficult decisions facing ...
Ashwin Reddy, Mukesh Jain, Vikas Khetan
doaj  

Cancer incidence and stage at diagnosis in children and adolescents in the Community of Madrid, 2015–2018

open access: yesPaediatric and Perinatal Epidemiology, EarlyView.
Abstract Background Cancer is the leading cause of death in children aged 1–14 and the second in 15‐19‐year‐old adolescents in Spain. The Paediatric Population‐Based Cancer Registry of the Community of Madrid was created to monitor its incidence and survival.
Raquel López‐González   +5 more
wiley   +1 more source

Molecular Classification Based on the Gene Expression Profiles in Canine Histiocytic Sarcoma Cells

open access: yesVeterinary and Comparative Oncology, EarlyView.
ABSTRACT The molecular abnormalities of canine histiocytic sarcoma (CHS) remain to be elucidated. We previously revealed that the sensitivities to dasatinib and trametinib were significantly various among CHS cell lines, indicating the differences in underlying molecular abnormalities. In the present study, we performed RNA sequencing analysis using 11
Hiroki Sakuma   +5 more
wiley   +1 more source

Urothelial carcinoma: Perioperative considerations from top to bottom

open access: yesCA: A Cancer Journal for Clinicians, EarlyView.
Abstract Urothelial carcinoma is an aggressive entity that is associated with significant morbidity, but there have been major advances in both our understanding of and treatment options for patients with this disease. In this review, the authors focus on novel therapeutic and diagnostic approaches in the perioperative setting, with an emphasis on ...
Wesley Yip   +8 more
wiley   +1 more source

Human sporadic breast carcinoma histotypes driven by the Human Betaretrovirus homologous to Mouse Mammary Tumor Virus

open access: yesInternational Journal of Cancer, Volume 157, Issue 2, Page 371-383, 15 July 2025.
What's new? While estrogens, obesity, and alcohol are recognized risk factors for breast cancer, a viral hypothesis has been suggested based on the murine model of Mouse Mammary Tumor Virus (MMTV)‐induced mammary tumors. This study analyzed sequences of the human homolog of MMTV across human breast carcinoma histotypes, detecting the virus in all types
Prospero Civita   +12 more
wiley   +1 more source

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