Results 141 to 150 of about 122,282 (250)

Exposure to per‐ and polyfluoroalkyl substances in residential settled dust and risk of childhood acute lymphoblastic leukemia

open access: yesInternational Journal of Cancer, Volume 157, Issue 1, Page 103-115, 1 July 2025.
What's new? Because of widespread use and resistance to degradation, per‐ and polyfluoroalkyl substances (PFAS) are ubiquitous in the environment. For young children, owing in part to crawling and hand‐to‐mouth behaviors, PFAS exposure is unique. Here, the authors investigated the risk of childhood leukemia in relation to PFAS found in settled dust ...
Catherine Metayer   +6 more
wiley   +1 more source

Retinoblastoma: The Evidence Does Matter

open access: yesCellular Oncology, 2009
Nadia L. Prigoda-Leea   +6 more
doaj   +1 more source

Glutamine Metabolism: Molecular Regulation, Biological Functions, and Diseases

open access: yesMedComm, Volume 6, Issue 7, July 2025.
Tumor cells adapt to nutrient‐poor environments by altering metabolism to acquire essential nutrients. They convert glutamine into glutamate and α‐ketoglutarate, supporting mTOR activation and sugar biosynthesis. Disruption of mTORC1 signaling is linked to disease, while glutamine and leucine activation promotes cell growth and inhibits autophagy ...
Mudasir A. Kumar   +10 more
wiley   +1 more source

Transforming Growth Factor‐β Pathway: Biological Functions and Therapeutic Targets

open access: yesMedComm, Volume 6, Issue 7, July 2025.
Natural compounds modulate the TGF‐β pathway, which acts as both a tumor suppressor and promoter during cancer progression. Agents such as ginsenosides, halofuginone, and EGCG influence cell proliferation, apoptosis, and angiogenesis. These bioactive molecules may complement standard therapies, highlighting the need for advanced formulations ...
Reham Hassan Mekky   +9 more
wiley   +1 more source

Late Mortality Among Survivors of Childhood Cancer in Canada: A Retrospective Cohort Study

open access: yesPediatric Blood &Cancer, Volume 72, Issue 7, July 2025.
ABSTRACT Background Children with cancer face an increased risk of complications and death beyond the 5‐year survival mark. National surveillance efforts facilitate the systematic tracking of long‐term health outcomes, including treatment‐related complications and late mortality, among childhood cancer survivors.
Katherine McKenzie   +5 more
wiley   +1 more source

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