Results 161 to 170 of about 122,282 (250)

Phosphorylation State of RB Modulates Ferroptotic Sensitivity

open access: yesCell Biochemistry and Function, Volume 43, Issue 6, June 2025.
ABSTRACT Tumor suppressor RB is a central regulator of cell cycle progression. By binding to E2F transcription factors, RB can inhibit transcription of E2F target genes to cause cell cycle arrest. Cyclin dependent kinases (CDK) regulate the interaction of RB/E2F by phosphorylating RB at multiple sites.
Nishanth Kuganesan   +3 more
wiley   +1 more source

Risk of childhood brain tumors after exposure to CT radiation: A nationwide population‐based case–control study in Finland

open access: yesInternational Journal of Cancer, Volume 156, Issue 11, Page 2148-2157, 1 June 2025.
What's new? This population‐based case‐control study quantifies the risk of childhood brain tumors following exposure to radiation from computed tomography scans in Finland. Leveraging comprehensive nationwide cancer and computed tomography data and addressing key limitations in previous research, including reverse causation and confounding by ...
Jad Abuhamed   +4 more
wiley   +1 more source

Chromosomes of metastatic retinoblastoma. [PDF]

open access: bronze, 1987
H. Daly   +4 more
openalex   +1 more source

Pleiotropic Effects of Metformin on the Chemotherapy Response of HPV‐Positive Cancer Cells

open access: yesJournal of Medical Virology, Volume 97, Issue 6, June 2025.
ABSTRACT Improved treatment strategies for HPV‐positive cancers are urgently required. The viral E6/E7 oncoproteins are essential for the proliferation of HPV‐positive cancer cells and considered attractive therapeutic targets. Metformin is proposed to be repurposed for cancer therapy, but this is under controversial debate.
Alicia Avenhaus   +8 more
wiley   +1 more source

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