Results 241 to 250 of about 83,475 (294)
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The American Journal of Medicine, 1989
The retinoids, a group of compounds consisting of vitamin A and its derivatives, have been the subject of intense investigation over the past 30 years. These molecules have shown beneficial effects in the areas of acne, psoriasis, neoplastic processes and, most recently, reversal of extrinsically aged skin.
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The retinoids, a group of compounds consisting of vitamin A and its derivatives, have been the subject of intense investigation over the past 30 years. These molecules have shown beneficial effects in the areas of acne, psoriasis, neoplastic processes and, most recently, reversal of extrinsically aged skin.
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Annual Review of Nutrition, 1995
Vitamin A is a necessary nutrient in the diet. However, excessive doses of retinoids by pregnant women result in teratogenesis. In this chapter, we initially discuss the occurrence and characteristics of fetal malformations associated with maternal ingestion of natural and synthetic retinoids in both experimental animals and humans.
Kenneth J. Soprano +1 more
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Vitamin A is a necessary nutrient in the diet. However, excessive doses of retinoids by pregnant women result in teratogenesis. In this chapter, we initially discuss the occurrence and characteristics of fetal malformations associated with maternal ingestion of natural and synthetic retinoids in both experimental animals and humans.
Kenneth J. Soprano +1 more
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Annual Review of Pharmacology and Toxicology, 1999
Either an excess or a deficiency of vitamin A and related compounds (retinoids) causes abnormal morphological development (teratogenesis). Potential retinoid sources come from dietary intake, nutritional supplements, and some therapeutic drugs. Therefore, understanding the mechanisms of retinoid teratogenesis is important.
Michael D. Collins, Gloria E. Mao
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Either an excess or a deficiency of vitamin A and related compounds (retinoids) causes abnormal morphological development (teratogenesis). Potential retinoid sources come from dietary intake, nutritional supplements, and some therapeutic drugs. Therefore, understanding the mechanisms of retinoid teratogenesis is important.
Michael D. Collins, Gloria E. Mao
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50 Years of Topical Retinoids for Acne: Evolution of Treatment
American Journal of Clinical Dermatology, 2021H. Baldwin +5 more
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British Journal of Dermatology, 1992
Extensive well-controlled clinical studies performed over the past 5 years have demonstrated a consistent, dose-dependent, statistically significant improvement in the appearance of photodamaged skin after 3-6 months of daily treatment with topical 0.001-0.1% tretinoin cream.
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Extensive well-controlled clinical studies performed over the past 5 years have demonstrated a consistent, dose-dependent, statistically significant improvement in the appearance of photodamaged skin after 3-6 months of daily treatment with topical 0.001-0.1% tretinoin cream.
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Role of retinoids in differentiation and carcinogenesis.
Cancer Research, 1983It has been known for more than 50 years that retinoids, the family of molecules comprising both the natural and synthetic analogues of retinol, are potent agents for control of both cellular differentiation and cellular proliferation (70).
Michael B. Spom, A. Roberts
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Nutrition Reviews, 2009
Retinoids are a group of naturally occurring and synthetic compounds with vitamin A-like biological activity. They play an important role in vision, reproduction, growth, and epithelial cell differentiation. Recent discoveries of specific retinoid cellular binding proteins and nuclear receptors have led to a better (although not complete) understanding
Barbara A. Gilchrest, Tanya Futoryan
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Retinoids are a group of naturally occurring and synthetic compounds with vitamin A-like biological activity. They play an important role in vision, reproduction, growth, and epithelial cell differentiation. Recent discoveries of specific retinoid cellular binding proteins and nuclear receptors have led to a better (although not complete) understanding
Barbara A. Gilchrest, Tanya Futoryan
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Retinoid Specificity of Interphotoreceptor Retinoid-Binding Protein
Biochemistry, 1994Interphotoreceptor retinoid-binding protein (IRBP), the predominant protein in the interphotoreceptor matrix of retina, has been implicated in transfer of retinoids between retinal pigment epithelium and photoreceptor cells. In this work, the interactions of several retinoids with IRBP were studied in order to clarify whether the protein displays ...
Yong Chen, Noa Noy
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European Urology, 1999
Over several decades, in vitro experimental studies have demonstrated that retinoids effect the process of carcinogenesis and tend towards the alteration of cells back to more normal differentiation. This hypothesis has formed the basis of several chemopreventive studies in breast cancer, cervical cancer, head and neck cancer and lung cancer ...
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Over several decades, in vitro experimental studies have demonstrated that retinoids effect the process of carcinogenesis and tend towards the alteration of cells back to more normal differentiation. This hypothesis has formed the basis of several chemopreventive studies in breast cancer, cervical cancer, head and neck cancer and lung cancer ...
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Hormone Research, 1995
The observation that topical retinoic acid could attenuate wrinkles and other features of skin photoageing has projected this molecule into the media spotlight. Behind this effect are in fact major basic biological issues related to the role of retinoids in tissue maintenance and their possible interference with the molecular biology of cellular ageing.
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The observation that topical retinoic acid could attenuate wrinkles and other features of skin photoageing has projected this molecule into the media spotlight. Behind this effect are in fact major basic biological issues related to the role of retinoids in tissue maintenance and their possible interference with the molecular biology of cellular ageing.
openaire +3 more sources