Crystal structure of liganded and unliganded forms of bovine plasma retinol-binding protein.
The three-dimensional structures of bovine plasma retinol-binding protein (bRBP) complexed with retinol (space group P2(1)2(1)2(1), a = 46.08, b = 49.12, c = 76.10 A) and of the unliganded protein prepared in vitro by extracting retinol with ethyl ether (
Giuseppe Zanotti +2 more
semanticscholar +1 more source
Inhaled Halogen-Induced Oxidative Renal Damage and Dysfunction: A Lung Heart Kidney Axis. [PDF]
Mechanisms of lung‐heart‐kidney interaction in inducing organ injury after chemical inhalation. Acute exposure to halogen gases causes extensive lung injury and acute cardiac damage leading to fatalities. Formation of highly reactive halogenated molecules in the pulmonary bed and their circulation resulting in oxidative stress and inflammation was ...
Juncos JXM +9 more
europepmc +2 more sources
Crystallographic studies on complexes between retinoids and plasma retinol-binding protein.
The three-dimensional structures of complexes between bovine plasma retinol-binding protein (RBP) and three retinol analogs with different end groups (fenretinide, all-trans retinoic acid, and axerophthene) have been determined to 1.8-1.9-A resolution ...
G. Zanotti +5 more
semanticscholar +1 more source
Neuronal human BACE1 knock-in induces systemic diabetes in mice [PDF]
Acknowledgements The authors thank S. Tammireddy (Diabetes and Cardiovascular Science, University of the Highlands and Islands, Inverness, UK) for technical support with the lipidomics component. Funding We would like to thank R.
Dekeryte, Ruta +12 more
core +4 more sources
Retinol-binding protein: the transport protein for vitamin A in human plasma [PDF]
Vitamin A circulates in human plasma as retinol bound to a specific transport protein. This protein differs from the known low and high density plasma lipoproteins and has a hydrated density greater than 1.21. In order to study this protein, volunteers were injected intravenously with retinol-15-(14)C.
M, Kanai, A, Raz, D S, Goodman
openaire +2 more sources
Background Associations of proteinuria with low-level urinary cadmium (Cd) are currently interpreted as the sign of renal dysfunction induced by Cd. Few studies have considered the possibility that these associations might be non causal and arise from ...
Lison Dominique +6 more
doaj +1 more source
Placental transfer of a hydroxylated polychlorinated biphenyl and effects on fetal and maternal thyroid hormone homeostasis in the rat [PDF]
Earlier studies at our laboratory indicated that several hydroxylated polychlorinated biphenyls (OH-PCBs) detected in human blood could specifically inhibit thyroxine (T4) transport by competitive binding to the thyroid hormone transport protein ...
Assink, Y. +7 more
core +4 more sources
EARLY PREDICTORS OF RENAL DYSFUNCTION IN Β-THALASSEMIA MAJOR AND INTERMEDIA PATIENTS
Background: Better survival of thalassemia patients allowed previously unrecognized renal complications to emerge. Objectives: Assess prevalence and early predictors of renal dysfunction in young β-thalassemia major (β-TM) and intermedia (β-TI) patients.
Azza A.G. Tantawy +3 more
doaj +1 more source
Transthyretin levels in the vitreous correlate with change in visual acuity after vitrectomy [PDF]
Background/aim: Little is known about biochemical markers related to change in visual acuity after vitrectomy. The potential use of transthyretin (TTR), a carrier of the retinol/retinol-binding protein, as a biochemical marker protein, was investigated ...
De Letter, Els +7 more
core +3 more sources
It has been well established that retinol-binding protein (RBP) circulates as a 1:1 molar complex with thyroxine-binding prealbumin (PA) in mammalian (1) and avian plasma (2).
Y. Shidoji, M. Watanabe, Y. Muto
semanticscholar +1 more source

