Results 151 to 160 of about 59,714 (265)

Integrative Transcriptomics and Machine Learning Identify Temporal Stress Signatures and Astrocytic Neurocan Associated With Hypothalamic Injury

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 10, October 2026.
Our research journey revealed a clear split: mRNAs track stress stages, while miRNAs sense stress states. We built a validated predictive model from just 6 markers. The star was Ncan—an astrocytic proteoglycan—which restored neuronal nets and eased depression; virtual knockout confirmed its central role in stress networks.
Weihao Zhu   +6 more
wiley   +1 more source

Population Genomic Analysis in Wild Medaka Populations: Identifying Candidate Loci for Balancing Selection

open access: yesEcology and Evolution, Volume 16, Issue 10, October 2026.
We explored genomic signatures of balancing selection and selective sweep in the northern medaka, Oryzias sakaizumii in Japan by performing whole‐genome resequencing of wild individuals. In addition, we reevaluated the population genetic structure and admixture of Oryzias latipes and O.
Shingo Fujimoto   +9 more
wiley   +1 more source

Relative Validity of Food Frequency Questionnaires in Adult Populations: A Systematic Review and Meta‐Analysis

open access: yesFood Science &Nutrition, Volume 14, Issue 10, October 2026.
This meta‐analysis demonstrates that digital Food Frequency Questionnaires are reliable tools for ranking habitual dietary intake in adults. Validation against 24‐h recalls and food records shows moderate‐to‐good correlation coefficients, particularly for carbohydrates and fiber. Factors such as interviewer administration and higher item counts enhance
Carmelo Pujia   +8 more
wiley   +1 more source

Integrated Multi‐Omics and Single‐Cell Analyses Implicate NOX4 as an Icariin‐Associated Oxidative Stress Regulatory Node in Gastric Cancer

open access: yesFood Science &Nutrition, Volume 14, Issue 10, October 2026.
NOX4 represents a candidate icariin‐associated regulatory node in gastric cancer and may contribute to the cellular response to icariin through redox‐related signaling. ABSTRACT Icariin, a prenylated flavonoid glycoside from Epimedium species, is a representative dietary polyphenol with antioxidant, anti‐inflammatory, and antitumor properties.
Na Liang   +8 more
wiley   +1 more source

Oral Retinol, Alone or Combined with Medical Photoprotection, in Patients with Actinic Keratosis: A Randomized, Open-Label, Prospective, Multicentric Study. [PDF]

open access: yesDermatol Ther (Heidelb)
Ardigò M   +8 more
europepmc   +1 more source

Dietary Inflammatory Potential and Continence‐Related Symptoms: Cross‐Sectional and Longitudinal Analyses of Three Population Studies

open access: yesFood Science &Nutrition, Volume 14, Issue 10, October 2026.
Dietary inflammatory potential and continence‐related symptoms across NHANES, ELSA, and CLHLS. Higher dietary scores were associated with existing symptoms in the main analyses, whereas prospective analyses showed no clear associations with incident outcomes. Differences in populations, dietary measures, and outcomes limit direct comparison.
Mengmeng Jiang   +4 more
wiley   +1 more source

Human biomarker navigator

open access: yesiMeta, Volume 5, Issue 5, October 2026.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Efficacy of Fermented Brown Rice by Aspergillus oryzae (FBRA) in Ulcerative Colitis: A Double‐Blind Randomized Trial

open access: yesJGH Open, Volume 10, Issue 10, October 2026.
ABSTRACT Background Ulcerative colitis (UC) is a diffuse, nonspecific inflammation of the colon of unknown cause. Basic and clinical studies suggest that UC may be ameliorated by dietary fiber intake. Fermented brown rice by Aspergillus oryzae (FBRA) is produced by fermenting brown rice and bran with A. oryzae. We aimed to evaluate the efficacy of FBRA
Hideki Ishikawa   +5 more
wiley   +1 more source

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