Results 41 to 50 of about 59,714 (265)
Vitamin A metabolism: analysis of steady-state neutral metabolites in rat tissues.
Journal of Lipid Research, 1984 High-performance liquid chromatography systems were developed to rapidly separate retinol from its esters, analyze the total spectrum of neutral vitamin A compounds, and purify retinyl esters to homogeneity.
J B Williams, B C Pramanik, J L Napoli
doaj +1 more source
Retinol-Binding Protein Interferes with Transthyretin-Mediated β‑Amyloid Aggregation Inhibition
, 2018 β-Amyloid (Aβ) aggregation is causally linked to Alzheimer’s disease. On the basis of in vitro and transgenic animal studies, transthyretin (TTR) is hypothesized to provide neuroprotection against Aβ toxicity by binding to Aβ and inhibiting its ...
Regina M. Murphy +3 more
core +1 more source
Transport of retinol in the duck plasma [PDF]
, 1981 . Retinol-binding protein and prealbumin were isolated from duck plasma by chromatography on DEAE-cellulose-and DEAE-Sephadex A-50, gel filtration on Sephadex G-100 and preparative Polyacrylamide gel electrophoresis.
N. Appaji Rao +8 more
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Explore the role and prospects of retinol in modern medicine - A review of obesity, type 2 diabetes, and cancer [PDF]
E3S Web of ConferencesThis paper reviews the applications of retinol in modern medicine, with a particular focus on its role in obesity, type 2 diabetes, and cancer treatment.
Hao Zixin, Tang Ziyue, Xia Yutian
doaj +1 more source
Retinol-binding protein 4 in polycystic ovary syndrome--association with steroid hormones and response to pioglitazone treatment [PDF]
, 2009 CONTEXT: Polycystic ovary syndrome (PCOS) is frequently associated with insulin resistance. OBJECTIVE: The aim of the study was to investigate a putative role of the adipokines retinol-binding protein 4 (RBP4), adiponectin, and visfatin in a cohort of ...
Aigner, Elmar +6 more
core +1 more source
Repurposing a Small Molecule Plant Hormone as a Tunable ON‐Switch for CAR‐T Cell Immunotherapy
Advanced Science, EarlyView.By engineering a receptor system integrating the plant auxin receptor AFB1 with its co‐receptor IAA7, we enable ligand‐dependent interactions triggered by the plant hormone auxins. This design allows rapid, reversible, and dose‐dependent T cell activation, resulting in potent cytotoxicity against B‐cell lymphoma in vitro and in vivo.
Hongxiang Zeng +16 more
wiley +1 more source
Retinol Binding Protein, Sunlight Hours, and the Influenza Virus-Specific Immune Response
Biomedicines, 2022 Healthy pediatric immune responses depend on adequate vitamin A and D levels. Relationships between solar ultraviolet B (UVB) radiation and vitamin D are well understood, while relationships between sunlight, vitamin A, and its serum escort, retinol ...
Nehali Patel +7 more
doaj +1 more source
Advanced Science, EarlyView.A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie +7 more
wiley +1 more source
Interactions of retinol with lipid bilayers: studies with vesicles of different radii.
Journal of Lipid Research, 1995 The interactions of retinol with vesicles of dioleoylphosphatidylcholine of varying radii were studied. The rate constants of dissociation of retinol from bilayers (k(off)) and the equilibrium partition constants (Keq) of retinol into bilayers of ...
N Noy, D J Kelleher, A W Scotto
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Advanced Science, EarlyView.Coexisting DCIS and IDC samples are profiled using spatial transcriptomics, single‐cell RNA sequencing, and single‐cell DNA sequencing. Integrative multi‐omics analysis reveals distinct malignant epithelial and microenvironmental features between DCIS and IDC, which are further validated using Xenium and multiplex immunohistochemistry.
Ning Zhang +18 more
wiley +1 more source