Results 161 to 170 of about 37,733 (224)

Anemia, micronutrient deficiency, and elevated biomarkers of inflammation among women and children in two districts in the Northern Region of Ghana: A pilot study. [PDF]

PLoS One
Adu-Afarwuah S, Kumordzie SM, Wessells KR, Arnold CD, Tan X, Fuseini A, Vosti SA, Haskell MJ, Becher ER, Davis JN, Adams KP, Engle-Stone R.   +11 more
europepmc   +1 more source

Amelioration of Liver Fibrosis via In Situ Hepatic Stellate Cell Conversion Through Co‐Inhibition of TGF‐β and GSK‐3 Signalling

Liver International, Volume 45, Issue 7, July 2025.
ABSTRACT Background and Aims Liver fibrosis, a progressive condition driven by chronic liver injury and excessive scar tissue formation, can lead to cirrhosis, a life‐threatening disease. Activation of hepatic stellate cells (HSCs) is central to fibrosis progression, yet current therapies fail to halt or reverse this process.
Xiang‐Jie Zhu, Zhi Zhong, Jiang‐Chuan Du, Jiu‐Yu Zhang, Xu Zhang, Xiu‐Liang Cui, Ling‐Ting Guan, Yan‐Yu Hu, Can Chen, Han Wang, Xiang‐Yu Wu, Wei‐Jia Zhang, Pei‐Lin Zhang, Hong‐Yang Wang   +13 more
wiley   +1 more source

Association between vitamin A status, inflammations, and infections in children 36-59 months of age in rural Burkina Faso: A cross - sectional study. [PDF]

J Health Popul Nutr
Sombié OO, Zeba AN, Somé JW, Kazienga A, Bationo JF, Davis C, Tanumihardjo SA, De Henauw S, Abbeddou S.   +8 more
europepmc   +1 more source

Germline Disruption of Retinal Pigment Epithelium‐Expressed Zebrafish rlbp1b−/− Results in Selective Dim Light Visual Behavior Deficits and Provides a Screening Platform for Evaluating the Pathogenicity of Human RLBP1 Variants

The FASEB Journal, Volume 39, Issue 12, 30 June 2025.
RLBP1 is a gene that is mutated in several different inherited retinal diseases (IRDs). Here we investigate the consequences of loss of RPE expressed zebrafish Cralbpb using CRISPR knockout models. These consequences include impaired dim light OKR behaviour, altered retinoid profiles, and a disrupted proteomic profile.
John D. Fehilly, Tess McCann, Grace Ruddin, Joanna J. Kaylor, Hannah Grenville, Rebecca Ward, Kieran Wynne, Alicia Gómez Sánchez, Elin Strachan, Gabriel H. Travis, Ross F. Collery, Breandán N. Kennedy   +11 more
wiley   +1 more source

Unraveling the causal pathway between phosphatidylinositol, metabolites, and metabolic syndrome: a Mendelian randomization study. [PDF]

Diabetol Metab Syndr
Yang Y, Ma Y, Li M, Han Y, Liu L.
europepmc   +1 more source

Identification of Plasma Free Fatty Acid Carrier Proteins in Mice

The FASEB Journal, Volume 39, Issue 12, 30 June 2025.
Plasma free fatty acid (FFA) transport had been believed to solely depend on albumin. However, we recently discovered that albumin knockout (Alb−/−) mice still have meaningful levels of plasma FFAs, indicating the presence of other FFA carrier proteins.
Keigo Tomoo, Yi Zhang, Rodrigo Mohallem, Uma K. Aryal, Jeffery B. Klauda, Gregory C. Henderson   +5 more
wiley   +1 more source

Integrated cascade antioxidant nanozymes-Cu_5.4O@CNDs combat acute liver injury by regulating retinol metabolism. [PDF]

Theranostics
Chen J, Zhang Y, Deng Z, Zhu Y, Xu C, Gao B, Wang W, Xiao J, Xiao Z, Zhang M, Tu K.   +10 more
europepmc   +1 more source

Advances and therapeutic opportunities in visual cycle modulation. [PDF]

Prog Retin Eye Res
Zaluski J, Bassetto M, Kiser PD, Tochtrop GP.   +3 more
europepmc   +1 more source

Urine Proteomics for Detection of Potential Biomarkers for End-Stage Renal Disease. [PDF]

Int J Mol Sci
Silva NR, Picolo BU, de Sousa LCM, Dos Santos MS, Polveiro RC, Almeida-Souza HO, Martins MM, Goulart Filho LR, da Silva LS.   +8 more
europepmc   +1 more source

Vitamin A Metabolism and Resistance of Hepatic Metastases to Immunotherapy. [PDF]

Mol Cancer Ther
Jones PC, Von Hoff DD.
europepmc   +1 more source