Results 61 to 70 of about 40,792 (218)

Retinal Pigment Epitheliopathy due to Sub‐Optimal Recycling of Vitamin A (RESORVA): A Novel RDH11‐Related Phenotype

Clinical Genetics, EarlyView.
RDH11 is a minor isoenzyme that catalyses the oxidation of 11‐cis‐retinol to 11‐cis‐retinal in the retinal pigment epithelium, alongside RDH5 and RDH10. Biallelic null variants in RDH11 lead to upregulation of RDH5 and RDH10 (transcriptional adaptation), maintaining 11‐cis‐retinal bioavailability, but still causing Retinal Pigment Epitheliopathy due to
Kirk A. J. Stephenson, Zhuo Shao, Anupreet Tumber, Erika Tavares, Kashif Ahmed, Edward J. Higginbotham, Christian R. Marshall, Jason T. Maynes, Ammaji Rajala, Raju V. S. Rajala, Elise Héon, Ajoy Vincent   +11 more
wiley   +1 more source

Serum retinol concentration and prevalence of vitamin A deficiency in postpartum women - doi:10.5020/18061230.2011.p40

Revista Brasileira em Promoção da Saúde, 2012
Objective: To check the serum retinol concentration and assess the nutritional status of postpartum women assisted at Januario Cicco Maternity School, Natal / RN in relation to vitamin A deficiency.
Juliana Cristina de Oliveira Dantas, Ana Caroline Perez Medeiros, Karla Danielly da Silva Ribeiro Rodrigues, Roberto Dimenstein   +3 more
doaj   +1 more source

Retinoic Acid Signalling Regulates Zebrafish Tooth Germ Repair Following Injury

Cell Proliferation, EarlyView.
Retinoic acid signalling may regulate the repair processes in a tooth germ injury model using Tg(scpp5:Dendra2‐NTR) zebrafish and the nitroreductase (NTR)/metronidazole (MTZ) system. ABSTRACT Although the role of retinoic acid (RA) signalling in odontogenesis is well established, its involvement in the repair of injured tooth germs remains unclear.
Qiqi Liu, Zhenan Zhang, Weifeng Hao, Chunyan Zhou, Deqin Yang   +4 more
wiley   +1 more source

Adipocyte HSL is required for maintaining circulating vitamin A and RBP4 levels during fasting

EMBO Reports
Vitamin A (retinol) is distributed via the blood bound to its specific carrier protein, retinol-binding protein 4 (RBP4). Retinol-loaded RBP4 is secreted into the circulation exclusively from hepatocytes, thereby mobilizing hepatic retinoid stores that ...
Julia S Steinhoff, Carina Wagner, Henriette E Dähnhardt, Kristina Košić, Yueming Meng, Ulrike Taschler, Laura Pajed, Na Yang, Sascha Wulff, Marie F Kiefer, Konstantin M Petricek, Roberto E Flores, Chen Li, Sarah Dittrich, Manuela Sommerfeld, Hervé Guillou, Andrea Henze, Jens Raila, Sylvia J Wowro, Gabriele Schoiswohl, Achim Lass, Michael Schupp   +21 more
doaj   +1 more source

Retinol metabolism in rats with low vitamin A status: a compartmental model

Journal of Lipid Research, 1990
A compartmental model was developed to describe the metabolism of vitamin A in rats with low vitamin A status maintained by a low dietary intake of vitamin A (approximately 2 micrograms retinol equivalents/day).
KC Lewis, MH Green, JB Green, LA Zech
doaj   +1 more source

Novel Histopathologic Features of Diffuse Blue‐Gray Hyperpigmentation Associated With Kratom Use: A Case Report and Literature Review

Journal of Cutaneous Pathology, EarlyView.
ABSTRACT Background Drug‐induced hyperpigmentation accounts for 10%–20% of acquired pigmentary disorders and can be misdiagnosed for other causes such as melasma, post inflammatory changes, or heavy metal deposition. Kratom (Mitragyna speciosa), a Southeast Asian plant with an opioid‐like profile, has been increasingly used in the United States for ...
Rita Kamoua, Kristen Paradine, Craig A. Rohan, Mary McDaniel, Diane Perkins   +4 more
wiley   +1 more source

Aetiological relevance of haematological, biochemical and endocrine parameters on equine odontoclastic tooth resorption and hypercementosis (EOTRH)

Equine Veterinary Journal, EarlyView.
Abstract Background The dental syndrome EOTRH is a painful, progressive dental disease with an unknown aetiology. The often painful nature of EOTRH emphasises the need for a better knowledge of the underlying pathogenic mechanism and risk factors. A comparative analysis of haematological, biochemical and endocrine values in EOTRH‐affected and non ...
Melusine Tretow, Anna M. Hain, Astrid Bienert‐Zeit   +2 more
wiley   +1 more source

Resúmenes de investigaciones nacionales. Nutrición normal y terapéutica

Perspectivas en Nutrición Humana, 2008
Objetivo: evaluar el efecto del suplemento de retinol sobre citocinas en niños con malaria vivax no complicada. Metodología: estudio piloto, experimental, balanceado no ciego, con asignación aleatoria del "factor de exposición" (recibir o no, suplemento ...
Viviana Milena Taylor Orozco, Rosa Magdalena Uscátegui Peñuela, Jaime Carmona Fonseca, Adriana Correa Botero   +3 more
doaj  

Serum retinol concentration in patients with acute falciparum malaria

Journal of Infection in Developing Countries, 2009
Background: Vitamin A (retinol)-deficiency and falciparum malaria are two major public health problems in developing countries. Falciparum malaria is associated with significant destruction of erythrocytes and can lead to severe anaemia.
Adil Raza, Haris M Khan, Mohd. Ashraf Malik, Abbas Ali Mahdi, Mohd. Shahid, Fatima Shujatullah   +5 more
doaj   +1 more source

A supramolecular assembly of cone‐specific G‐protein and cryptochrome 4a on lipid bilayer

The FEBS Journal, EarlyView.
Immobilized phospholipid bilayers on a sensor chip surface serve as membrane platform to investigate critical protein–lipid and protein–protein interaction processes by surface plasmon resonance. The putative magnetoreceptor cryptochrome 4a and the myristoylated cone‐specific G‐protein α‐subunit (Gtα) bind with high affinity to immobilized lipid ...
Ümmügülsüm Güzelsoy‐Flügge, Srđan Vujinović, Alexander Scholten, Karl‐Wilhelm Koch   +3 more
wiley   +1 more source