Results 61 to 70 of about 37,733 (224)
ChemMedChem, EarlyView.Several derivatives incorporating five‐membered aromatic rings are described in this review as bile acid receptor modulators, particularly targeting the farnesoid X receptor and the G protein‐coupled bile acid receptor 1. This review provides a comprehensive analysis of patents and literature that is useful to support researchers in the design of new ...
Claudia Finamore +5 more
wiley +1 more source
A phenomap of TTR amyloidosis to aid diagnostic screening
ESC Heart Failure, Volume 12, Issue 2, Page 1113-1118, April 2025.Abstract Cardiac amyloidosis due to transthyretin (ATTR) remains an underdiagnosed cause of cardiomyopathy. As awareness of the disease grows and referrals for ATTR increase, clinicians are likely to encounter more atypical forms of the condition in clinical practice.
Alexios S. Antonopoulos +4 more
wiley +1 more source
Uptake and metabolism of retinol (vitamin A) in the isolated perfused rat liver
Journal of Lipid Research, 1965 The isolated perfused liver was employed to study various aspects of retinol-C14 metabolism. The rate of uptake of retinol, retinal, retinoic acid, and retinol acetate was rapid (first-order rate constant, k = 0.12–0.16 min−1) during the first 3–10 min ...
Richard D. Zachman, James Allen Olson
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Dry Eye Disease: Oxidative Stress on Ocular Surface and Cutting‐Edge Antioxidants
Global Challenges, Volume 9, Issue 7, July 2025.This review has systematically evaluated the oxidative damage of cornea, tear film, lacrimal gland, conjunctiva and meibomian gland for dry eye, and concluded the antioxidants that are either commercially available or in the research phase. GQDs: Graphene quantum dots; LF: lactoferrin; ROS: Reactive oxygen species; SOD: Superoxide dismutase; tFNA ...
Rong Hu +3 more
wiley +1 more source
Nanosecond spectroscopy of retinol.
Journal of Biological Chemistry, 1975 Nanosecond fluorescence spectroscopy was used to study the unique binding site of the retinol-binding protein (RBP) from human serum. At pH 7.4, the binding of retinol to RBP caused the following spectroscopic changes in the ligand: (a) an enhancement of the fluorescence decay time (gamma = 8 ns); and (b) an increase in the emission anisotropy (A = 0 ...
J E Churchich, S Georghiou
openaire +3 more sources
Data in Brief, 2018 Retinol is transported in vertebrate plasma bound to a protein called retinol-binding protein (RBP4) so far believed to be specific for the vitamin. When the protein is saturated with retinol it binds tightly to another plasma protein, transthyretin ...
Massimiliano Perduca +4 more
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Diverse Subpopulations of Reactive Astrocytes Following Chronic Toxoplasma Infection
Glia, EarlyView.Toxoplasma infection results in distinct astrocyte subpopulations. Chronically labeled reactive astrocytes appear transcriptionally plastic and can regain acute inflammatory responding and naive homeostatic astrocytic gene patterns in the presence of ongoing neuroinflammation.
Zoe A. Figueroa +7 more
wiley +1 more source
A multicompartmental model of vitamin A kinetics in rats with marginal liver vitamin A stores.
Journal of Lipid Research, 1985 A linear, first-order, constant-coefficient multicompartmental model is presented which describes the dynamics of [3H]retinol turnover in adult rats with normal plasma retinol concentrations but low liver stores (less than 100 micrograms of retinol ...
M H Green, L Uhl, J B Green
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Revista Brasileira em Promoção da Saúde, 2012 Objective: To check the serum retinol concentration and assess the nutritional status of postpartum women assisted at Januario Cicco Maternity School, Natal / RN in relation to vitamin A deficiency.
Juliana Cristina de Oliveira Dantas +3 more
doaj +1 more source
Retinol esterification by mammary gland microsomes from the lactating rat.
Journal of Lipid Research, 1982 Because vitamin A in milk is largely present as esterified retinol while blood plasma predominantly contains unesterified retinol, experiments were conducted to determine whether membranes from the lactating mammary gland are able to synthesize retinyl ...
A C Ross
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