Results 111 to 120 of about 42,988 (215)

Metabolic Engineering of Komagataella Phaffii for de Novo Synthesis of Retinol From Methanol. [PDF]

Biotechnol J
Wu Y, Liu C, Liang S, Jiang Y, Zhang X, Zhou Y, Lin Y.   +6 more
europepmc   +1 more source

Aetiology‐Specific Pancreatic Enzyme Dose Requirements and Treatment Outcomes in Pancreatic Exocrine Insufficiency: The Multicentre EURO‐PEI Registry

United European Gastroenterology Journal, Volume 14, Issue 8, October 2026.
ABSTRACT Background Pancreatic exocrine insufficiency (PEI) is a maldigestion syndrome leading to symptoms and nutritional deficiencies. Prospective real‐world data on pancreatic enzyme replacement therapy (PERT) dose requirements across aetiologies are limited. Objective To define PERT dose requirements and treatment outcomes across PEI aetiologies in
J. Enrique Domínguez‐Muñoz, Yessica Domínguez‐Novoa, Xurxo Martínez‐Seara, Peter Hegyi, Vinciane Rebours, Mary E. Phillips, Federico Bolado, Gabriele Capurso, Giulia de Marchi, Keith J. Roberts, Orsolya Eperjesi, Sandra Salmeron, David Ruiz‐Clavijo, Gaetano Lauri, Alessandro Brillo, Sarah Powell‐Brett, Jose Lariño‐Noia, Julio Iglesias‐García   +17 more
wiley   +1 more source

Oral Retinol, Alone or Combined with Medical Photoprotection, in Patients with Actinic Keratosis: A Randomized, Open-Label, Prospective, Multicentric Study. [PDF]

Dermatol Ther (Heidelb)
Ardigò M, Burlando M, Campione E, Nazzaro G, Foggi G, Colombo F, Alfano S, Milani M, Marzano AV.   +8 more
europepmc   +1 more source

Metabolic Dysfunction‐Associated Steatotic Disease and Genetic Risk in Germany—An Observational Real‐World Cohort Study

United European Gastroenterology Journal, Volume 14, Issue 8, October 2026.
ABSTRACT Background Metabolic dysfunction‐associated steatotic disease (MASLD) affects increasing numbers of patients worldwide. The PNPLA3 p.I148M variant represents a major genetic determinant of MASLD progression. The loss‐of‐function HSD17B13 polymorphism rs72613567 was reported in turn to be hepatoprotective.
Marcin Krawczyk, Frank Grünhage, Lisa Schubert, Nektarios Dikopoulos, Jeannette Schwenzer, Marion Muche, Johannes Wiegand, Gisela Felten, Renate Heyne, Patrick Ingiliz, Anna Schmidt, Kerstin Stein, Susanne N. Weber, Heiner Wedemeyer, Stefan Zeuzem, Peter Buggisch, Frank Lammert, Andreas Geier, Wolf Peter Hofmann, Jörn M. Schattenberg   +19 more
wiley   +1 more source

Transplantation of Elderly Human Gut Microbiota Into Pigs Reprograms Intestinal Barrier Function, Plasma Metabolome, and Gut Mucosal Transcriptomic Landscape

Aging Cell, Volume 25, Issue 10, October 2026.
Elderly human donor microbiota disrupts intestinal barrier integrity and reshapes host metabolic and mucosal transcriptional profiles in human microbiota‐associated pigs. Integrated multi‐omics analyses identify coordinated microbial, metabolic, and host alterations associated with age‐related intestinal decline.
Jiaxin Wang, Lingyu Li, Lihua Mei, Zhining Tang, Baorui Liao, Qianye Zhao, Yuzeng Wang, Qingyao Fu, Liu Ren, Zhian Zhai, Yifei Xu, Aoyu Yang, Shuai Duan, Zhengyuan Zhai, Yanling Hao, Yalin Zhou, Yajun Xu, Ying Yang, Zhenlong Wu, Yun Ji   +19 more
wiley   +1 more source

Intracellular Retinoid-Binding Proteins (CRBP, CRALBP, CRABP) as Emerging Drug Targets in Retinal Disease. [PDF]

Int J Mol Sci
Regmi Bagale L, Kim HJ.
europepmc   +1 more source

Vitamins and Chronic Wounds: How Altered Pharmacokinetics and Comorbidities Contribute to Vitamin Deficiencies

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.
ABSTRACT Wound healing is complex and requires adequate amounts of macro‐ and micronutrients. When wound healing is delayed, a wound is considered chronic. Increasing evidence shows that vitamin deficiencies are prevalent in patients with chronic wounds, yet intervention studies with vitamin supplementation yielded inconsistent effects.
Michiel G. J. Balvers, Teuntje L. de Smit, Anne I. Slotegraaf, Remy H. H. Bemelmans, Joé L. P. Kolkert, Tim J. Schuijt, Renger F. Witkamp   +6 more
wiley   +1 more source

Novel Histopathologic Features of Diffuse Blue‐Gray Hyperpigmentation Associated With Kratom Use: A Case Report and Literature Review

Journal of Cutaneous Pathology, Volume 53, Issue 10, Page 887-892, October 2026.
ABSTRACT Background Drug‐induced hyperpigmentation accounts for 10%–20% of acquired pigmentary disorders and can be misdiagnosed for other causes such as melasma, post inflammatory changes, or heavy metal deposition. Kratom (Mitragyna speciosa), a Southeast Asian plant with an opioid‐like profile, has been increasingly used in the United States for ...
Rita Kamoua, Kristen Paradine, Craig A. Rohan, Mary McDaniel, Diane Perkins   +4 more
wiley   +1 more source

Effect of Dietary Vitamin A, Breed, and Kidney Function on the Onset of Urinary Vitamin A Excretion and the Vitamin A Transport Complex in Growing Dogs. [PDF]

J Anim Physiol Anim Nutr (Berl)
Raila J, Özpinar H, Schweigert FJ.
europepmc   +1 more source

mRNA Therapeutics for Skin Rejuvenation: From Aging Atlases to Clinical Translation

Experimental Dermatology, Volume 35, Issue 10, October 2026.
ABSTRACT Skin aging is a multifactorial process characterized by the progressive decline of tissue structure, function and regenerative capacity. Although numerous interventions have been developed to improve the clinical manifestations of aging, most primarily alleviate downstream consequences rather than directly targeting the molecular mechanisms ...
Fabiana Boncimino, Stefano Sol, Kristina Todorova, Anna Mandinova   +3 more
wiley   +1 more source