Results 121 to 130 of about 16,489,844 (220)

Maternal protein restriction programs the ageing kidney: Proteomic signatures of early‐life origin renal and metabolic dysfunction

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Maternal protein restriction (MPR) induced persistent renal histopathological alterations accompanied by elevated serum creatinine levels. Nephron‐segment proteomic analysis revealed region‐specific molecular dysregulation affecting Bowman's capsule (PARK7, oxidative stress sensor; MSN, cytoskeletal organization), the proximal ...
Marina Pereira Pires   +15 more
wiley   +1 more source

Müller Glia Subtypes Define Neuro‐Glial Associations and Spatial Morphogen Axes in the Zebrafish Retina

open access: yesGlia, Volume 74, Issue 11, November 2026.
Zebrafish Müller glia are heterogeneous in the early larval retina. Zebrafish Müller glia subtypes define a spatial axis of retinoic acid metabolism. Neuron‐associated glial programs identified in Zebrafish Müller glia are evolutionarily conserved in mammals. ABSTRACT Müller glia are instrumental macroglia of the vertebrate retina, once thought to be a
Samuel S. Storey   +3 more
wiley   +1 more source

Prealbumin and Retinol-Binding Protein 4: The Promising Inflammatory Biomarkers for Identifying Endoscopic Remission in Crohn’s Disease

open access: yesJournal of Inflammation Research, 2021
Rirong Chen,1,* Li Li,1,* Chao Li,2 Yuhan Su,2 Yingfan Zhang,1 Xiaobai Pang,2 Jieqi Zheng,2 Zhirong Zeng,1 Min-Hu Chen,1 Shenghong Zhang1 1Division of Gastroenterology, The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, People’s ...
Chen R   +9 more
doaj  

DreamFold: A World Model to efficiently generate protein folding pathways in the latent space

open access: yesProtein Science, Volume 35, Issue 11, November 2026.
Abstract While there is an abundance of static data for the structure of biological macromolecules, the data regarding their folding mechanisms and dynamics is scarce, posing a challenge to the training of AI models. The World Model approach, which has been very successful in robotics, can come in handy in this regard. From limited data, it can build a
Alan Ianeselli   +3 more
wiley   +1 more source

Serum Amyloid A is a Retinol Binding Protein that Transports Retinol during Bacterial Infection [PDF]

open access: yes, 2016
Retinol plays a vital role in the immune response to infection, however it remains unclear which proteins mediate retinol transport during infection. Serum amyloid A (SAA) proteins are produced by the liver following acute systemic infection and are ...
Zlatkov, Clare Marie
core   +1 more source

Integrated Multi‐Omics and Single‐Cell Analyses Implicate NOX4 as an Icariin‐Associated Oxidative Stress Regulatory Node in Gastric Cancer

open access: yesFood Science &Nutrition, Volume 14, Issue 10, October 2026.
NOX4 represents a candidate icariin‐associated regulatory node in gastric cancer and may contribute to the cellular response to icariin through redox‐related signaling. ABSTRACT Icariin, a prenylated flavonoid glycoside from Epimedium species, is a representative dietary polyphenol with antioxidant, anti‐inflammatory, and antitumor properties.
Na Liang   +8 more
wiley   +1 more source

Znaczenie wybranych adipokin w łuszczycy

open access: yesPrzegląd Dermatologiczny, 2011
Psoriasis is a chronic and recurrent skin disease, affecting 1.5-3% of thepopulation. It is characterized by abnormal epidermal proliferation,immunological disturbances with predominance of Th1 response andcomplex pathogenesis.
Anna Baran   +2 more
doaj  

Vitamins and Chronic Wounds: How Altered Pharmacokinetics and Comorbidities Contribute to Vitamin Deficiencies

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 139, Issue 4, October 2026.
ABSTRACT Wound healing is complex and requires adequate amounts of macro‐ and micronutrients. When wound healing is delayed, a wound is considered chronic. Increasing evidence shows that vitamin deficiencies are prevalent in patients with chronic wounds, yet intervention studies with vitamin supplementation yielded inconsistent effects.
Michiel G. J. Balvers   +6 more
wiley   +1 more source

Is serum retinol binding protein-4: A predictor for diabetes in genetically high risk population?

open access: yesJournal of Research in Medical Sciences, 2012
Background: Retinol binding protein-4 (BP-4) a new adipocytokine, specifically binds to retinol, through experimental studies, reported its link between obesity and insulin resistance (IR).
K Subhash Chandra Bose   +2 more
doaj  

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