The Clinical Significance of Urinary Retinol-Binding Protein 4: A Review. [PDF]
Int J Environ Res Public Health, 2022 Effective biomarkers for early diagnosis, prognostication, and monitoring in renal diseases (in general) comprise an unmet need. Urinary retinol-binding protein 4, which is the most sensitive indicator of renal tubular damage, holds great promise as a universal biomarker for renal pathologies, in which tubular injury is the driving force.
Ratajczyk K +8 more
europepmc +5 more sources
Retinol Binding Protein 4 and Pathogenesis of Diabetes [PDF]
The Journal of Clinical Endocrinology & Metabolism, 2007 Obesity is an important risk factor for a number of chronic diseases that impose a huge burden on individuals and society. Recently it has become clear that adipose tissue-secreted products may play a significant role in mediating many obesity-related ...
Philip G. McTernan, Sudhesh Kumar
openaire +3 more sources
Role of retinol-binding protein 4 in obese Asian Indians with metabolic syndrome [PDF]
Journal of Medical Biochemistry, 2012 Retinol-binding protein 4 is an adipocytokine separately implicated in the development of obesity-related insulin resistance and proatherogenic lipid profile, however, its role in humans is unclear.
Shivakumar Nirupama +8 more
doaj +2 more sources
High resolution crystal structure data of human plasma retinol-binding protein (RBP4) bound to retinol and fatty acids [PDF]
Data in Brief, 2018 Retinol is transported in vertebrate plasma bound to a protein called retinol-binding protein (RBP4) so far believed to be specific for the vitamin. When the protein is saturated with retinol it binds tightly to another plasma protein, transthyretin ...
Massimiliano Perduca +4 more
doaj +2 more sources
Relationship of Retinol Binding Protein Four Serum Level on Endometrial Hyperplasia and Endometrial Carcinoma [PDF]
Indonesian Journal of Obstetrics and Gynecology, 2018 Objective : To determine the relationship of elevated serum retinol binding protein 4 with abnormal uterine bleeding Methods : This study was an observational quantitative with cross sectional methods, with all women who had abnormal uterine bleeding ...
Ivan Limy +2 more
doaj +2 more sources
Retinol Binding Protein 4 in Non Obese Psoriatic Cases [PDF]
Journal of Clinical and Diagnostic Research, 2016 Ola Ahmed Bakry +3 more
doaj +3 more sources
Atherosclerosis, 2010 Retinol is transported in a complex with retinol-binding protein 4 (RBP4) and transthyretin (TTR) in the circulation. While retinol is associated with various cardiovascular risk factors, the relation between retinol, RBP4, TTR and carotid intima media thickness (IMT) has not been analysed yet.Retinol, RBP4 and TTR were measured in 96 individuals and ...
Bobbert, Thomas +7 more
openaire +3 more sources
Retinol and Retinol Binding Protein 4 Levels and Cardiometabolic Disease Risk. [PDF]
Circ Res, 2022 Background: Despite mechanistic studies linking retinol and RBP4 (retinol binding protein 4) to the pathogenesis of cardiovascular diseases (CVD) and type 2 diabetes (T2D), epidemiological evidence is still conflicting. We investigated whether conflicting results of previous studies may be explained by differences in the ...
Schiborn C +10 more
europepmc +7 more sources
Retinol-binding protein-4 was associated with sensitization to inhalant allergens in the elderly population [PDF]
The Korean Journal of Internal Medicine, 2021 Background/Aims Recent evidence suggests an association between allergic sensitization and metabolic markers. However, this association has rarely been examined in the elderly.
Byung-Keun Kim +7 more
doaj +1 more source
Identification of Transthyretin Tetramer Kinetic Stabilizers That Are Capable of Inhibiting the Retinol-Dependent Retinol Binding Protein 4-Transthyretin Interaction [PDF]
, 2021 Dissociation of transthyretin (TTR) tetramers may lead to misfolding and aggregation of pro-amyloidogenic monomers, which underlies TTR amyloidosis (ATTR) pathophysiology.
Arun, Raja +7 more
core +1 more source