Adipocytokine levels mark endothelial function in normotensive individuals
Cardiovascular Diabetology, 2012 Background Endothelial dysfunction is an independent risk factor for cardiovascular events. Inflammatory mediators released by the adipose tissue can lead to local insulin resistance and endothelial dysfunction.
Solini Anna +6 more
doaj +1 more source
Cysteine-10 on 17 β-Hydroxysteroid dehydrogenase 1 has stabilizing interactions in the cofactor binding region and renders sensitivity to sulfhydryl modifying chemicals [PDF]
, 2013 17 β-Hydroxysteroid dehydrogenase type 1 (17 β -HSD1) catalyzes the conversion of estrone to the potent estrogen estradiol. 17 β -HSD1 is highly expressed in breast and ovary tissues and represents a prognostic marker for the tumor progression and ...
Atanasov, Atanas G. +3 more
core +3 more sources
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2018 Background Adipokines mediate cardiometabolic risk associated with obesity but their role in the pathogenesis of obesity‐associated heart failure remains uncertain.
Beatrice von Jeinsen +6 more
doaj +1 more source
Quantitative mass spectrometry evaluation of human retinol binding protein 4 and related variants. [PDF]
PLoS ONE, 2011 Retinol Binding Protein 4 (RBP4) is an exciting new biomarker for the determination of insulin resistance and type 2 diabetes. It is known that circulating RBP4 resides in multiple variants which may provide enhanced clinical utility, but conventional ...
Urban A Kiernan +3 more
doaj +1 more source
Is the Retinol-Binding Protein 4 a Possible Risk Factor for Cardiovascular Diseases in Obesity?
International Journal of Molecular Sciences, 2020 Although many preventive and treatment approaches have been proposed, cardiovascular disease (CVD) remains one of the leading causes of deaths worldwide.
A. Rychter +8 more
semanticscholar +1 more source
Retinol-Binding Protein-4 in Women With Untreated Essential Hypertension
American Journal of Hypertension, 2009 Retinol-binding protein-4 (RBP4) is a novel adipokine able to modulate the action of insulin in several tissues. A variable degree of insulin resistance characterizes the vast majority of hypertensive (HYP) patients. The aim of this study was to evaluate the relationship between RBP4 and essential hypertension, exploring potential links between RBP4 ...
SOLINI, ANNA +4 more
openaire +3 more sources
Inflammation Research, 2020 Retinol binding protein 4 (RBP4) is a member of the lipocalin family and a vitamin A carrier in the blood. More recently, RBP4 has been described as an adipokine that is involved in insulin resistance and metabolic syndrome (MetS).
M. Scotece +7 more
semanticscholar +1 more source
Pulse of inflammatory proteins in the pregnant uterus of European polecats (Mustela putorius) leading to the time of implantation [PDF]
, 2017 Uterine secretory proteins protect the uterus and conceptuses against infection, facilitate implantation, control cellular damage resulting from implantation, and supply pre-implantation embryos with nutrients.
Burchmore, Richard J.S. +2 more
core +1 more source
Sexual dimorphism in developmental and diet‐dependent circulating retinol binding protein 4
Obesity Science & Practice, 2018 Summary Objective Retinol binding protein 4 (RBP4) transports vitamin A (Retinol) in the blood and contributes mechanistically to the linkage between obesity, insulin resistance and associated comorbidities including type 2 diabetes mellitus, coronary ...
S. Bakshi +7 more
doaj +1 more source
Decreased Retinol Binding Protein 4 Concentrations are Associated With Cholesterol Gallstone Disease
Journal of the Formosan Medical Association, 2010 Circulating retinol binding protein 4 (RBP4) is associated with a variety of obesity-related diseases. This study investigated whether there were aberrant concentrations of RBP4 in cholesterol gallstone disease.
Shen-Nien Wang +6 more
doaj +1 more source