Results 31 to 40 of about 5,652,471 (282)

Emergence of highly profibrotic and proinflammatory Lrat+Fbln2+ HSC subpopulation in alcoholic hepatitis

Hepatology, EarlyView., 2022
Lrat+ quiescent hepatic stellate cells (qHSC) give rise to Lrat+Fbln2+ activated HSC (aHSC) in alcohol‐associated hepatitis and this subpopulation is highly profibrotic, inflammatory, and immunoregulatory based on their single cell transcriptomic profile. Abstract Background and Aims Relative roles of HSCs and portal fibroblasts in alcoholic hepatitis (
Steven Balog, Reika Fujiwara, Stephanie Q. Pan, Khairat B. El‐Baradie, Hye Yeon Choi, Sonal Sinha, Qihong Yang, Kinji Asahina, Yibu Chen, Meng Li, Matthew Salomon, Stanley W.‐K. Ng, Hidekazu Tsukamoto   +12 more
wiley   +1 more source

Adipokine Retinol Binding Protein 4 and Cardiovascular Diseases

Frontiers in Physiology, 2022
The morbidity and mortality of cardiovascular diseases (CVDs) have been increasing year by year all over the world and expanding greatly to the younger population, which becomes the leading causes of death globally that threatens human life safety ...
Yanjing Ji, Jinyou Song, Tianhong Su, Xiaosong Gu   +3 more
doaj   +1 more source

Retinol-binding protein 2 (RBP2): biology and pathobiology

Critical reviews in biochemistry and molecular biology, 2020
Retinol-binding protein 2 (RBP2; originally cellular retinol-binding protein, type II (CRBPII)) is a 16 kDa cytosolic protein that in the adult is localized predominantly to absorptive cells of the proximal small intestine.
W. Blaner, P. Brun, Rossana M. Calderon, M. Golczak   +3 more
semanticscholar   +1 more source

A rapid versatile microassay for cellular retinol-binding protein using Lipidex-1000 microcolumns.

Journal of Lipid Research, 1990
A new, rapid and versatile microassay for cellular retinol-binding protein has been developed based on separation of bound and free ligand by means of Lipidex-1000, a hydrophobic Sephadex derivative.
A M Timmers, D A van Groningen-Luyben, F J Daemen, W J De Grip   +3 more
doaj   +1 more source

Proxy markers of serum retinol concentration, used alone and in combination, to assess population vitamin A status in Kenyan children: a cross-sectional study [PDF]

, 2015
Background Serum retinol concentration determined by high-performance liquid chromatography (HPLC) is recommended by the World Health Organization to assess population vitamin A status.
Inge D Brouwer, Verhoef, H., Elise F Talsma, Alida Melse-Boonstra, Brouwer, Inge D, Hulshof, Paul JM, Talsma, E.F., Anne S Mburu-de Wagt, Paul JM Hulshof, Hans Verhoef, Talsma, Elise F, Mburu-de Wagt, Anne S, Melse-Boonstra, Alida, Brouwer, I.D., Hulshof, P.J.M., Mburu-de Wagt, A.S., Verhoef, Hans, Boonstra, A., Talsma, E.F.; Verhoef, H.; Brouwer, I.D.; Mburu-de Wagt, A.S.; Hulshof, P.J.M.; Melse-Boonstra, A.   +18 more
core   +2 more sources

Retinol-binding protein 4 in polycystic ovary syndrome--association with steroid hormones and response to pioglitazone treatment [PDF]

, 2009
CONTEXT: Polycystic ovary syndrome (PCOS) is frequently associated with insulin resistance. OBJECTIVE: The aim of the study was to investigate a putative role of the adipokines retinol-binding protein 4 (RBP4), adiponectin, and visfatin in a cohort of ...
Aigner, Elmar, Patsch, Wolfgang, Bachofner, Nora, Klein, Kerstin, Datz, Christian, Hohla, Florian, De Geyter, Christian   +6 more
core   +1 more source

Cellular retinol-binding protein (type two) is abundant in human small intestine.

Journal of Lipid Research, 1987
Human small intestine was found to contain a retinol-binding protein similar to the gut-specific cellular retinol-binding protein, type two [CRBP (II)], described in the rat.
D E Ong, D L Page
doaj   +1 more source

Retinol‐induced secretion of human retinol‐binding protein in yeast [PDF]

FEBS Letters, 1998
Retinol‐binding protein (RBP) functions as a transporter for retinol (vitamin A) in plasma in higher eukaryotes. We have successfully expressed human RBP in Saccharomyces cerevisiae, and its secretion was found to be induced by retinol also in this lower eukaryote. Reduced induction of secretion by retinol in a temperature‐sensitive sec18‐1 mutant that
Reppe, Sjur, Smeland, Sigbjørn, Moskaug, Jan Ø, Blomhoff, Rune   +3 more
openaire   +2 more sources

The Transfer of Retinol from Serum Retinol-binding Protein to Cellular Retinol-binding Protein Is Mediated by a Membrane Receptor [PDF]

Journal of Biological Chemistry, 1998
The hypothesis that the cellular uptake of retinol involves the specific interaction of a plasma membrane receptor with serum retinol-binding protein (RBP) at the extracellular surface followed by ligand transfer to cytoplasmic cellular retinol-binding protein (CRBP) has been investigated.
M, Sundaram, A, Sivaprasadarao, M M, DeSousa, J B, Findlay   +3 more
openaire   +2 more sources

Cellular retinoid-binding proteins in reginerating rat liver: demonstration of a novel cellular retinoid-binding protein.

Journal of Lipid Research, 1981
Changes in the levels of liver cellular aetinol- and retinoic acid-binding proteins were studied after partial (about 70%) hepatectomy for 14 days in the rat.
M Omori, Y Muto, T Nagao
doaj   +1 more source