Results 41 to 50 of about 4,223,808 (257)

Role of retinol-binding protein 4 in obese Asian Indians with metabolic syndrome [PDF]

Journal of Medical Biochemistry, 2012
Retinol-binding protein 4 is an adipocytokine separately implicated in the development of obesity-related insulin resistance and proatherogenic lipid profile, however, its role in humans is unclear.
Shivakumar Nirupama, Kumar Jaya Meghanaa, Aswathanarayan Narasimhaiah Manasa, Venkatesh Sosale Maanasa, Sheshadri Manasa, Deshmukh Shreehari, Srinivasan Honnavara Pranav, Dharmalingam Mala, Marcus Rani Sara   +8 more
doaj  

Metabolism and secretion of retinol transport complex in acute renal failure

Journal of Lipid Research, 1991
Tissue uptake and distribution of retinol from circulatory vitamin A transport complex was studied in order to determine the origin of the increased serum retinol in rats with short-term acute renal failure.
TH Gerlach, MH Zile
doaj   +1 more source

Retinol and Retinol Binding Protein 4 Levels and Cardiometabolic Disease Risk

Circulation Research, 2022
Background: Despite mechanistic studies linking retinol and RBP4 (retinol binding protein 4) to the pathogenesis of cardiovascular diseases (CVD) and type 2 diabetes (T2D), epidemiological evidence is still conflicting. We investigated whether conflicting results of previous studies may be explained by differences in the ...
Catarina Schiborn, Daniela Weber, Tilman Grune, Ronald Biemann, Susanne Jäger, Natascha Neu, Marie Müller von Blumencron, Andreas Fritsche, Cornelia Weikert, Matthias B. Schulze, Clemens Wittenbecher   +10 more
openaire   +6 more sources

An immortalized rat liver stellate cell line (HSC-T6): a new cell model for the study of retinoid metabolism in vitro

Journal of Lipid Research, 2000
Hepatocytes and hepatic stellate cells play important roles in retinoid storage and metabolism. Hepatocytes process postprandial retinyl esters and are responsible for secretion of retinol bound to retinol-binding protein (RBP) to maintain plasma retinol
Silke Vogel, Roseann Piantedosi, Jorge Frank, Avraham Lalazar, Don C. Rockey, Scott L. Friedman, William S. Blaner   +6 more
doaj   +1 more source

Retinol-binding protein-4 and nonalcoholic fatty liver disease

Chinese Medical Journal, 2022
. Nonalcoholic fatty liver disease (NAFLD) is becoming increasingly common as the global economy grows and living standards improve. Timely and effective preventions and treatments for NAFLD are urgently needed.
Hangkai Huang, Chengfu Xu, Yuanyuan Ji
doaj   +1 more source

Influência da resposta inflamatória de fase aguda nos níveis séricos de retinol e da proteína de ligação do retinol em pacientes com AIDS Influence of acute-phase inflammatory response on serum levels of retinol and retinol binding protein in HIV/AIDS patients

Revista da Sociedade Brasileira de Medicina Tropical, 2010
INTRODUÇÃO: a hiporretinolemia constitui fator prognóstico independente em pacientes com AIDS, e a atividade inflamatória causa redução dos níveis séricos deste nutriente na população em geral.
Fábio Fernandes Neves, José Fernando de Castro Figueiredo, Alceu Afonso Jordão Júnior, Hélio Vannucchi   +3 more
doaj   +1 more source

Função renal de pacientes de unidade de terapia intensiva: creatinina plasmática e proteína carreadora do retinol urinário Renal function of intensive care unit patients: plasma creatinine and urinary retinol-binding protein

Revista Brasileira de Terapia Intensiva, 2008
OBJETIVOS: A avaliação precoce da disfunção renal usando marcadores usuais não supre uma indicação quer da sensitividade e da especificidade da disfunção renal de pacientes críticos.
Cristina Satoko Mizoi, Cassiane Dezoti, Maria de Fátima Fernandes Vattimo   +2 more
doaj   +1 more source

A Functional Binding Domain in the Rbpr2 Receptor Is Required for Vitamin A Transport, Ocular Retinoid Homeostasis, and Photoreceptor Cell Survival in Zebrafish

Cells, 2020
Dietary vitamin A/all-trans retinol/ROL plays a critical role in human vision. ROL circulates bound to the plasma retinol-binding protein (RBP4) as RBP4-ROL. In the eye, the STRA6 membrane receptor binds to circulatory RBP4 and internalizes ROL. STRA6 is,
Ashish K. Solanki, Altaf A. Kondkar, Joseph Fogerty, Yanhui Su, Seok-Hyung Kim, Joshua H. Lipschutz, Deepak Nihalani, Brian D. Perkins, Glenn P. Lobo   +8 more
doaj   +1 more source

Retinol modulates site-specific mobility of apo-cellular retinol-binding protein to promote ligand binding

, 2006
A fundamental question in protein science is how the inherent dynamics of a protein influence its function. If this function involves interactions with a ligand, the protein-ligand encounter has the potential to modulate the protein dynamics.
MITTAG T, ROSSI, Gian Luigi, SCHAFFHAUSEN B, CAVAZZINI, Davide, FRANZONI, Lorella, GUNTHER UL   +5 more
core   +2 more sources

Bacterially Expressed Rat Retinol-binding Protein is Functional for Retinol and Transthyretin Bindings.

Journal of Nutritional Science and Vitaminology, 1996
Retinol-binding protein (RBP) was expressed in Escherichia coli using the cDNA for rat RBP, and characterized. The expressed RBP was fused to maltose-binding protein (MBP) at the N-terminal end (MBP-RBP), and MBP was enzymatically removed from the MBP-RBP with proteinase factor Xa.
YAMAMOTO, Yuji, YOSHIZAWA, Tatsuya, MANO, Hiroshi, MASUSHIGE, Shoichi, KATO, Shigeaki   +4 more
openaire   +3 more sources