Results 101 to 110 of about 50,629 (277)

Retinoic acid as a modulator of T cell immunity [PDF]

, 2016
Indexación: Scopus. DOAJ.Vitamin A, a generic designation for an array of organic molecules that includes retinal, retinol and retinoic acid, is an essential nutrient needed in a wide array of aspects including the proper functioning of the visual system,
Bono, M.R., Fernandez, D., Flores-Santibañez, F, Rosemblatt, M., Sauma, D., Tejon, G.   +5 more
core   +1 more source

Changes in Serum Levels of Retinol Binding Protein 4, Glucose and Insulin in Adaptation to Nettle Supplementation and Combination Training in Overweight Men With Type 2 Diabetes [PDF]

, 2021
Vahid Tayid, Aziz Zinivand Lorestani, Mahbanoo Ghaderi, Hadi Gharani, Yaser Mehdizadeh, Marzieh Havasi   +5 more
openalex   +1 more source

Retinol binding protein 4 – a novel association with early-onset preeclampsia [PDF]

Journal of Perinatal Medicine, 2010
Dysregulation of maternal circulating adipokines has been implicated in several "great obstetrical syndromes" including preeclampsia (PE), small-for-gestational age (SGA) neonate and fetal death (FD). It has been suggested that adipokines provide a molecular link between metabolic derangements and inflammatory response in complicated pregnancies ...
Edi, Vaisbuch, Roberto, Romero, Shali, Mazaki-Tovi, Offer, Erez, Sun Kwon, Kim, Tinnakorn, Chaiworapongsa, Francesca, Gotsch, Nandor Gabor, Than, Zhong, Dong, Percy, Pacora, Ronald, Lamont, Lami, Yeo, Sonia S, Hassan, Juan Pedro, Kusanovic   +13 more
openaire   +2 more sources

Vitamin A metabolism is changed in donors after living-kidney transplantation: an observational study

Lipids in Health and Disease, 2011
Background The kidneys are essential for the metabolism of vitamin A (retinol) and its transport proteins retinol-binding protein 4 (RBP4) and transthyretin.
Henze Andrea, Raila Jens, Kempf Caroline, Reinke Petra, Sefrin Anett, Querfeld Uwe, Schweigert Florian J   +6 more
doaj   +1 more source

Retinoid isomerase inhibitors impair but do not block mammalian cone photoreceptor function [PDF]

, 2018
Visual function in vertebrates critically depends on the continuous regeneration of visual pigments in rod and cone photoreceptors. RPE65 is a well-established retinoid isomerase in the pigment epithelium that regenerates rhodopsin during the rod visual ...
Angueyra, Juan M, Badiee, Mohsen, Kefalov, Vladimir J, Kinoshita, Junzo, Kiser, Philip D, Kolesnikov, Alexander V, Li, Wei, Palczewski, Krzysztof, Peachey, Neal S, Sharma, Aditya, Tochtrop, Gregory P, Zhang, Jianye   +11 more
core   +1 more source

Self-rated health in middle-aged and elderly Chinese : distribution, determinants and associations with cardio-metabolic risk factors [PDF]

, 2009
Background: Self-rated health (SRH) has been demonstrated to be an accurate reflection of a person's health and a valid predictor of incident mortality and chronic morbidity.
A Pan, A Pan, A Pan, A Quesnel-Vallee, A Singh-Manoux, An Pan, AT Beekman, BF Zhou, CA Cott, CL Craig, EL Idler, ES Yu, Huaixing Li, J Bond, J Zhang, JB Dowd, JC Levy, Jing Wang, KK Leung, LC Yu, LS Radloff, M Huisman, M Jylha, N Goldman, N Lin, Nazanin Haseli-Mashhadi, Oscar H Franco, Q Qi, Qibin Qi, SE Tomten, SM Grundy, ST Cheng, WY Lim, X Pei, X Ye, Xingwang Ye, Xu Lin, YH Cheng, Yong Liu, ZB Li, Zhijie Yu   +40 more
core   +3 more sources

Identification of genetically predicted protein biomarkers and drug targets for prostate cancer via Mendelian randomization

VIEW, EarlyView.
Prostate cancer, a leading cause of cancer in men globally, urgently requires improved diagnostic and treatment strategies. This study analyzed large genetic datasets and identified five key proteins (THBD, DST, IFI27L2, OSBPL10, PPP1R14A) that either increase or decrease cancer risk, while also exploring their roles in immune response and potential ...
Maoping Cai, Tianming Peng, Zhiyue Xie, Chuqian Zhen, Chen Yao, Nan Peng, Qianyi Li, Yuzhong Yu, Jiming Bao, Xian‐Lu Song, Mingkun Chen, Shan‐Chao Zhao   +11 more
wiley   +1 more source

Type 2 Diabetes Mellitus and Retinol-Binding Protein 4

Korean Diabetes Journal, 2008
New function of retinol-binding protein 4 (RBP4) was identified in addition to the traditional role as a vitamin A transport protein. In the state of insulin resistance even before the onset of type 2 DM, GLUT4 expression by adipocytes is decreased, but those by skeletal muscle is well preserved.
Won-Young Lee, Eun-Jung Rhee
openaire   +1 more source

An engineered epididymal cell line provides a sustainable source of functional extracellular vesicles for in vitro sperm preservation: A multi‐omics and functional study

VIEW, EarlyView.
ABSTRACT This study investigated the function of epididymal extracellular vesicles (EVs) in overcoming sperm post‐testicular modification deficiencies. Although EVs derived from the epididymis play a crucial role in intercellular communication and molecular exchange, there is limited research addressing how EVs released by in vitro cultured epididymal ...
Long Li, Haonan Zhao, Yibo Li, Qixin Xu, Yang Zi, Tingting Chu, Heran Cao, Shujuan Liu, Zifang Wu, Huanqiang Zhao, Wuzi Dong   +10 more
wiley   +1 more source

Blue light regenerates functional visual pigments in mammals through a retinyl-phospholipid intermediate. [PDF]

, 2017
The light absorbing chromophore in opsin visual pigments is the protonated Schiff base of 11-cis-retinaldehyde (11cRAL). Absorption of a photon isomerizes 11cRAL to all-trans-retinaldehyde (atRAL), briefly activating the pigment before it dissociates ...
Fain, Gordon L, Hakobyan, Hayk, Ingram, Norianne T, Kaylor, Joanna J, Travis, Gabriel H, Tsan, Avian, Xu, Tongzhou   +6 more
core   +1 more source