Results 111 to 120 of about 50,629 (277)

Retinol Binding Protein 4 (RBP4) in Adipocytes and Obesity

The FASEB Journal, 2019
We have earlier reported the generation and study of transgenic mice that express human RBP4 (hRBP4) in both white and brown adipocytes (Lee et al. Hepatology 2016, 64:1534–1546). Our published studies of these mice (adi‐hRBP4 mice) established that
Igor Shmarakov, Seung‐Ah Lee, William S. Blaner   +2 more
openaire   +1 more source

Infection control in the brain and the eye

Acta Ophthalmologica, EarlyView.
Abstract The Central Nervous System (CNS), comprising the brain and the eye, is considered to have a ‘privileged’ mechanism for dealing with immunological challenge (immune privilege, IP). CNS IP has been revealed through experiments using foreign protein antigens and cell and tissue alloantigens (grafts), but evidence for a role for IP in modulating ...
John V. Forrester, Paul G. McMenamin, Samantha J. Dando   +2 more
wiley   +1 more source

Review Article: Renal Safety Profiles of Tenofovir Alafenamide, Tenofovir Disoproxil Fumarate, and Entecavir for the Treatment of Chronic Hepatitis B Infection—General and Special Populations

Alimentary Pharmacology &Therapeutics, EarlyView.
Current first‐line NUCs show comparable renal safety profiles in CHB patients with no or mild kidney dysfunction, with growing evidence that favours TAF. Future prospective studies are needed to validate these findings, and more research should focus on CHB patients with diabetes mellitus who are at risk of CKD.
Lung‐Yi Mak, Tsung‐Hui Hu, Desmond Y. H. Yap   +2 more
wiley   +1 more source

Plasma retinol-binding protein 4 in the first and second trimester and risk of gestational diabetes mellitus in Chinese women: a nested case-control study

Nutrition & Metabolism, 2020
Background To assess the association between plasma retinol-binding protein 4 (RBP4) levels both in the first trimester and second trimester and risk of gestational diabetes mellitus (GDM).
Chuyao Jin, Lizi Lin, Na Han, Zhiling Zhao, Zheng Liu, Shusheng Luo, Xiangrong Xu, Jue Liu, Haijun Wang   +8 more
doaj   +1 more source

Examination of Fluconazole-Induced Alopecia in an Animal Model and Human Cohort. [PDF]

, 2019
Fluconazole-induced alopecia is a significant problem for patients receiving long-term therapy. We evaluated the hair cycle changes of fluconazole in a rat model and investigated potential molecular mechanisms.
Aaron, Phylicia A, Affolter, Verena K, Dennis, Michael, Everett, Angela D, Fedor, Dawn M, Gelli, Angie, Krois, Charles R, McHardy, Ian, Napoli, Joseph L, Sharon, Victoria R, Singapuri, Anil, Thompson, George R, Varjonen, E Katarina, White, Stephen D, Wiederhold, Nathan P, Yoo, Hong Sik   +15 more
core  

P745Adipokines retinol binding protein 4 and fatty-acid binding protein 4 in left ventricular hypertrophy

European Heart Journal, 2019
Abstract Background and aim Obese individuals have a high risk of developing heart failure independent of concomitant diseases like diabetes mellitus or arterial hypertension. Hormones secreted by adipose tissue, so-called adipokines such as retinol binding protein 4 (RBP4) or fatty-acid binding ...
B Von Jeinsen, L Ritzen, J Vietheer, C Unbehaun, M Weferling, C Liebetrau, C W Hamm, A Rolf, T Keller   +8 more
openaire   +1 more source

A supramolecular assembly of cone‐specific G‐protein and cryptochrome 4a on lipid bilayer

The FEBS Journal, EarlyView.
Immobilized phospholipid bilayers on a sensor chip surface serve as membrane platform to investigate critical protein–lipid and protein–protein interaction processes by surface plasmon resonance. The putative magnetoreceptor cryptochrome 4a and the myristoylated cone‐specific G‐protein α‐subunit (Gtα) bind with high affinity to immobilized lipid ...
Ümmügülsüm Güzelsoy‐Flügge, Srđan Vujinović, Alexander Scholten, Karl‐Wilhelm Koch   +3 more
wiley   +1 more source

Systemic, Lifestyle and Environmental Modifying Factors in the Pathogenesis of Periodontitis

Journal of Periodontal Research, EarlyView.
A variety of impacting factors in the pathogenesis of periodontitis exist, including systemic, lifestyle, and environmental factors. This review highlights the manifold mechanistic aspects of the link between the pathogenesis of periodontitis, addressing these numerous factors to supplement the long‐standing knowledge of the progression of the disease.
Groeger Sabine Elisabeth, Zhou Yuxi, Yong Jiawen, Wang Lei, Ruf Sabine, Meyle Joerg   +5 more
wiley   +1 more source

Retinol-binding protein 4 in cardiovascular diseases: mechanisms and therapeutic perspectives

Frontiers in Cardiovascular Medicine
Cardiovascular diseases (CVDs) continue to be the leading cause of mortality worldwide, highlighting the need for enhanced diagnostic tools to enable early intervention.
Jiefang Chen, Gaijie Chen, Xiaojing Xu, Jiewen Zhang, Feng Liu   +4 more
doaj   +1 more source

Transthyretin levels in the vitreous correlate with change in visual acuity after vitrectomy [PDF]

, 2009
Background/aim: Little is known about biochemical markers related to change in visual acuity after vitrectomy. The potential use of transthyretin (TTR), a carrier of the retinol/retinol-binding protein, as a biochemical marker protein, was investigated ...
De Letter, Els, Delanghe, Joris, Delanghe, S, Derycke, Lara, Geers, I, Van Aken, Elisabeth, van Enschot, T, Veckeneer, M   +7 more
core   +3 more sources