Results 211 to 220 of about 16,382,176 (245)

Structural and mutational analyses of protein–protein interactions between transthyretin and retinol-binding protein

open access: yesFEBS Journal, 2008
Transthyretin is a tetrameric binding protein involved in the transport of thyroid hormones and in the cotransport of retinol by forming a complex in plasma with retinol-binding protein.
Laura Cendron   +2 more
exaly   +3 more sources

Interactions with Retinol and Retinoids of Bovine Cellular Retinol-Binding Protein

open access: yesFEBS Journal, 1995
The interactions with retinol and retinol analogs of bovine cellular retinol-binding protein (CRBP) have been investigated, by means of fluorescence titrations, to obtain more information on the structural features of retinoid that may be required for ...
Rodolfo Berni   +2 more
exaly   +1 more source

Effects of retinol binding protein-4 on vascular endothelial cells

Biochemical and Biophysical Research Communications, 2011
The study was designed to investigate the effect of retinol binding protein (RBP)-4 on the phosphatidylinositol 3-kinase (PI3K) and mitogen-activated protein kinase (MAPK) pathways, which mediate the effects of insulin in vascular endothelial cells. The effects of RBP4 on nitric oxide (NO) and insulin-stimulated endothelin-1 (ET-1) secretion and on ...
Kohzo, Takebayashi   +3 more
openaire   +2 more sources

Circulating retinol-binding protein 4 and metabolic syndrome in the elderly

Wiener Medizinische Wochenschrift, 2011
Retinol-binding protein (RBP) 4, a human adipokine that specifically binds to retinol, has been reported to provide a link between obesity and insulin resistance. Plasma RBP4 concentration may be under the influence of age and obesity, but only a few studies has investigated this link in elderly individuals.
Nazanin, Mostafaie   +12 more
openaire   +2 more sources

Retinol-binding protein-4 in experimental and clinical metabolic disease

Expert Review of Molecular Diagnostics, 2008
Retinol-binding protein-4 (RBP4), a 21-kDa protein synthesized in the liver and adipose tissue, has recently been described as a murine adipokine involved in the development of insulin resistance. The expression of the gene encoding RBP4 was increased in the adipose tissue, but not in the liver, of insulin-resistant adipose GLUT4(-/-) mice and five ...
Maximilian, von Eynatten, Per M, Humpert
openaire   +2 more sources

Retinol-binding protein 4, insulin resistance and pregnancy

Metabolism, 2012
Sir, the recent publication on retinol-binding protein 4 (RBP4), insulin resistance (IR) and pregnancy is very interesting [1]. Khovidhunkit et al concluded, “Serum RBP4 levels in pregnancy are not associated with IR.” [1]. This report is very interesting but is discordant with previous reports. RBP4 is discussed in terms of its clinical correlation to
openaire   +2 more sources

Retinol-Binding Protein 4 in Patients with Gestational Diabetes Mellitus

Journal of Women's Health, 2010
It is still unknown if serum retinol-binding protein 4 (RBP4) relates to metabolic control and the occurrence of gestational diabetes mellitus (GDM). We studied RBP4 levels in patients with insulin-treated GDM and healthy pregnant women twice during pregnancy.Sixty-three women with GDM and 38 healthy pregnant women were included. Serum RBP4 levels were
Katharina, Klein   +7 more
openaire   +2 more sources

Retinol-binding protein 4 is not associated with insulin resistance in pregnancy

Metabolism, 2012
Retinol-binding protein 4 (RBP4) is an adipokine proposed to be specifically associated with insulin resistance (IR). We examined whether serum levels of RBP4 were associated with IR in pregnancy. One hundred seventy-two women with gestational diabetes mellitus (GDM) and 361 pregnant Thai women who did not have GDM but had a positive 50-g glucose ...
Weerapan, Khovidhunkit   +3 more
openaire   +2 more sources

Retinol-Binding Protein 4 and Insulin Resistance

New England Journal of Medicine, 2006
To the Editor: Graham et al. (June 15 issue)1 report that serum levels of retinol-binding protein 4 (RBP4) correlated with the magnitude of insulin resistance in various subjects. However, RBP4 and plasma insulin levels were dissociated in subjects who did not have an improvement in insulin sensitivity after exercise.1 Thus, we believe that the ...
openaire   +1 more source

Retinol‐binding protein 4 levels and susceptibility to ischaemic events in men

European Journal of Clinical Investigation, 2014
AbstractBackgroundMany efforts in cardiovascular medicine have been focused in the identification of patients at risk of developing an acute ischaemic event. Biomarker discovery studies have become an essential research area, being proteomic technologies an excellent tool for biomarker identification.
Cubedo, J   +5 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy