Results 131 to 140 of about 15,495 (243)
Background: Cardiometabolic disorders, notably primary hypertension and type 2 diabetes, present substantial global health challenges. The intricate interplay between metabolic and cardiovascular pathways has prompted extensive research into molecular ...
Anand G. Jadhao +2 more
doaj +1 more source
ABSTRACT HIV remains a significant public health issue, with 1.3 million new infections and 630,000 deaths annually, and 40.8 million people living with HIV (PLHIV) globally in 2024. Although antiretroviral therapy (ART) suppresses viral replication, it does not eradicate the virus, and metabolic dysregulation persists despite treatment.
Levanco K. Asia +4 more
wiley +1 more source
Dietary norbixin (0.15 g/kg) optimally promotes growth, immunocompetence, antioxidant defence, gut microbial balance, carotenoid accumulation, and overall nutritional quality in Macrobrachium nipponense. ABSTRACT Background Natural carotenoids have gained considerable attention in aquaculture due to their potential to enhance growth performance ...
Mohammad Ettefaghdoost +2 more
wiley +1 more source
DOI: https://doi.org/10.1079/BJN19960095Retinol-binding protein (RBP) and transthyretin (TTR) in the plasma, liver and kidney, retinol in plasma, and total vitamin A in the liver were measured in rats 6 weeks after diabetes mellitus had been induced by ...
Tuitoek, Prisca J. +3 more
core +1 more source
ABSTRACT Plant‐based antioxidants are widely incorporated into foods to retard oxidative deterioration and to deliver health‐related benefits. Yet, their in‐product and in vivo performance frequently diverges from predictions based on solution‐phase chemical assays, because matrix interactions, processing history, and host metabolism reshape both ...
Márcio Vargas‐Ramella +6 more
wiley +1 more source
Effects of acute chemical modification on STRA6-catalyzed retinol release from holo-RBP.
STRA6-catalzyed retinol release from holo-RBP causes a decline in retinol fluorescence. In all experiments, holo-RBP was added at 0 min. A and B. Effects of MTSEA-biotin treatment on the retinol release activity of STRA6-WT and STRA6-S385C, respectively.
Mariam Ter-Stepanian (478956) +4 more
core +1 more source
Retinoic Acid Signalling Regulates Zebrafish Tooth Germ Repair Following Injury
Retinoic acid signalling may regulate the repair processes in a tooth germ injury model using Tg(scpp5:Dendra2‐NTR) zebrafish and the nitroreductase (NTR)/metronidazole (MTZ) system. ABSTRACT Although the role of retinoic acid (RA) signalling in odontogenesis is well established, its involvement in the repair of injured tooth germs remains unclear.
Qiqi Liu +4 more
wiley +1 more source
The Biological Effects of Novel Synthetic Retinoids [PDF]
Naturally occurring Retinoids are known to play a role in many developmental processes in the early embryo as well as being a potent tool for in vitro differentiation of stem cells. The exogenous application of these naturally occurring retinoids as well
BUDGE, JAMES,JOHN,ROWLAND
core
Degradomics for large‐scale mechanistic insights on proteases and proteolysis in human health
Proteolysis has an important role in human disease but remains relatively unexplored. Degradomics, the uncovering of proteolysis in tissues, cells, and proteins, uses mass spectrometry‐based terminomics to identify protein termini occurring therein (forward degradomics) and to define the actions of proteases (reverse degradomics).
Daniel R. Martin +2 more
wiley +1 more source
Isolation and Partial Characterization of Human Placenta Retinol-binding Protein [PDF]
Retinol-binding protein (RBP) is the specific blood carrier protein for the transport of retinol (vitamin A). RBP is mainly synthesized in the liver, though several extrahepatic organs including the placenta may also synthesize RBP as high amounts of RBP
Odani, Shoji +9 more
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