Results 71 to 80 of about 7,318 (257)

Mass spectrometry in ocular drug research

Mass Spectrometry Reviews, Volume 45, Issue 1, Page 37-68, January/February 2026.
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo, Kati‐Sisko Vellonen, Arto Urtti, Tetsuya Terasaki, Anam Hammid, Paavo Honkakoski, Seppo Auriola   +6 more
wiley   +1 more source

Context-dependent compensation among phosphatidylserine-recognition receptors [PDF]

, 2017
Phagocytes express multiple phosphatidylserine (PtdSer) receptors that recognize apoptotic cells. It is unknown whether these receptors are interchangeable or if they play unique roles during cell clearance.
Han, Claudia Z, Lee, Chang Sup, Lysiak, Jeffrey J, Onengut-Gumuscu, Suna, Palczewski, Krzysztof, Penberthy, Kristen K, Perry, Justin SA, Ravichandran, Kodi, Raymond, Michael H, Rival, Claudia, Shankman, Laura S, Zhang, Jianye   +11 more
core   +3 more sources

Effects of Replacing Fish Meal With Plant Protein Sources in Diets With or Without Jack Mackerel Meal Inclusion on Growth Performance of Red Sea Bream (Pagrus major)

Aquaculture Nutrition, Volume 2026, Issue 1, 2026.
Due to stagnant production and high cost of fish meal (FM), feed nutritionists are seeking reliable and affordable alternatives. However, low‐FM diets often result in poor palatability, reduced feed consumption (FC), and impaired growth. This study investigates the effects of replacing FM with plant proteins in diets with or without jack mackerel meal (
Yu Jin Sim, Sung Hwoan Cho, Tae Woong Kwon, Hae Chan Shin, Hong Min Na, Yong Woo Kwon, Seong Woo Shin, Sang Hyun Lee, Ki Wook Lee, Jin Choi, Noah Esmaeili   +10 more
wiley   +1 more source

N-3 fatty acids and chylomicron metabolism in the rat

Journal of Lipid Research, 1997
Dietary n-3 fatty acids (FAs) reduce postprandial triacylglycerol concentrations in humans by unknown mechanisms. Our goals were to reproduce this phenomenon in the rat, and then to determine the mechanism.
W S Harris, B E Hustvedt, E Hagen, M H Green, G Lu, C A Drevon   +5 more
doaj   +1 more source

Coverage of Vitamin A Supplementation Among Children Aged 12–59 Months in Bangladesh: A Multilevel Logistic Regression Approach

International Journal of Clinical Practice, Volume 2026, Issue 1, 2026.
Background Vitamin A supplementation (VAS) is a national strategy to address vitamin A deficiency. Children aged 6–59 months receive vitamin A twice a year. Despite this, coverage of VAS remains a major public health challenge for children in Bangladesh, with multiple studies aiming to identify its primary risk factors.
Sohani Afroja, Md. Salauddin Khan, Abu Saleh Muhammad Nasim, Masudul Islam, Md. Murad Hossain, Priya Gusain   +5 more
wiley   +1 more source

Design, synthesis and in vitro degradation of a novel co-drug for the treatment of psoriasis [PDF]

, 2013
Psoriasis is a common, chronic and relapsing inflammatory skin disease. It affects approximately 2% of the western population and has no cure. Combination therapy for psoriasis often proves more efficacious and better tolerated than monotherapy with a ...
Alex White, Bos, Brandt, Charles Heard, Clark, Gordon, Lau, Liang, McGill, Peus, Wing Lau   +10 more
core   +4 more sources

Brain Transcriptomics Reveals Molecular Mechanisms of Cave Adaptation in Triplophysa Loaches

Ecology and Evolution, Volume 15, Issue 12, December 2025.
This study compares brain transcriptomes of cave (Triplophysa shilinensis) and surface‐dwelling (T. xiangshuingensis) loaches to uncover molecular adaptations to subterranean life. We identified widespread gene down‐regulation in the cave ecotype, with enriched pathways in energy metabolism, circadian rhythms, sensory perception, and body coloration ...
Chunqing Li, Longting Wu, Fang Hu, Shanyuan Chen, Heng Xiao   +4 more
wiley   +1 more source

Evaluation of the Effect of Topical Vitamin A Eye Ointment on Pain Reduction and Accelerated Healing of Corneal Defect After Photorefractive Keratectomy: A Prospective Randomized Controlled Study

Health Science Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background and Aims Photorefractive keratectomy (PRK) is commonly used for refractive errors but is associated with postoperative pain and delayed epithelial healing. Vitamin A has been shown to support epithelial regeneration and corneal wound healing.
Maryam Hajizadeh, Nasrin Masihpour, Shima Shalil‐Ahmadi   +2 more
wiley   +1 more source

Allosteric modulation of the substrate specificity of acyl-CoA wax alcohol acyltransferase 2

Journal of Lipid Research, 2017
The esterification of alcohols with fatty acids is a universal mechanism to form inert storage forms of sterols, di- and triacylglycerols, and retinoids. In ocular tissues, formation of retinyl esters is an essential step in the enzymatic regeneration of
Jason M. Arne, Made Airanthi K. Widjaja-Adhi, Taylor Hughes, Kevin W. Huynh, Josie A. Silvaroli, Sylwia Chelstowska, Vera Y. Moiseenkova-Bell, Marcin Golczak   +7 more
doaj   +1 more source

Retinoic acid as a modulator of T cell immunity [PDF]

, 2016
Indexación: Scopus. DOAJ.Vitamin A, a generic designation for an array of organic molecules that includes retinal, retinol and retinoic acid, is an essential nutrient needed in a wide array of aspects including the proper functioning of the visual system,
Bono, M.R., Fernandez, D., Flores-Santibañez, F, Rosemblatt, M., Sauma, D., Tejon, G.   +5 more
core   +1 more source