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Normal and pathological functions of mammalian retroelements [PDF]

Proceedings of the National Academy of Sciences, 2005
In a recent issue of PNAS, Garen and colleagues (1) reported that the RNA transcribed from the retroelement VL30 binds to the repressor protein PSF followed by disengagement of PSF from the repressed genes and activation of transcription (1–3).
openaire +2 more sources

Relationship of MicroRNAs with Transposable Elements in the Type 1 Diabetes Development

Архивъ внутренней медицины
The review article describes the involvement of epigenetic factors in type 1 diabetes mellitus (T1DM) etiopathogenesis. The disease is characterized by changes in expression of microRNAs that affect the transcription of genes involved in autoimmune ...
R. N. Mustafin
doaj +1 more source

A Retroelement Modifies Pre-mRNA Splicing [PDF]

, 2012
Kristina Becker +8 more
openalex +1 more source

Implications of Endogenous Retroelements in the Etiopathogenesis of Systemic Lupus Erythematosus [PDF]

, 2021
Kennedy C. Ukadike, Tomas Mustelin
openalex +1 more source

Neurodegenerative diseases reflect the reciprocal roles played by retroelements in regulating memory and immunity

Frontiers in Neuroscience
Tetrapod endogenous retroelements (ERE) encode proteins that have been exapted to perform many roles in development and also in innate immunity, including GAG (group specific antigen) proteins from the ERE long terminal repeat (LTR) family, some of which
Alan Herbert
doaj +1 more source

A Novel Family of Mobile Genetic Elements Is Limited to the Germline Genome in \u3cem\u3eTetrahymena Thermophila\u3c/em\u3e [PDF]

, 2002
In the ciliated protozoan Tetrahymena thermophila, extensive DNA elimination is associated with differentiation of the somatic macronucleus from the germline micronucleus.
Gershan, Jill A. +4 more
core +2 more sources

Multiple Transcriptional and Post-transcriptional Pathways Collaborate to Control Sense and Antisense RNAs of Tf2 Retroelements in Fission Yeast [PDF]