Results 161 to 170 of about 11,758 (252)

Sorting nexin 3 induces myocardial injury via promoting retromer-dependent nuclear trafficking of STAT3 [PDF]

, 2020
Jing Lü, Suowen Xu, Yuqing Huo, Yuehuai Hu, Juanjian Wang, Xiaolei Zhang, Duanping Sun, Panxia Wang, Zhuo-ming Li, Mengya Liang, Zhongkai Wu, Peiqing Liu   +11 more
openalex   +1 more source

Targeting VPS18 hampers retromer trafficking of PD-L1 and augments immunotherapy

Science Advances
Immune checkpoint inhibitors targeting programmed cell death 1 (PD-1) or programmed cell death-ligand 1 (PD-L1) have achieved impressive antitumor clinical outcomes.
Ting Dong, Huan-min Niu, Zhaojun Chu, Chengjun Zhou, Yinghui Gao, Mengqi Jia, Bin Sun, Xiaoxue Zheng, Wenru Zhang, Jiaozhen Zhang, Yanhai Luo, Yong Sun, Chan Wang, Qiqi Lu, Changhong Liu, Guangfeng Shao, Hongxiang Lou, Huiqing Yuan   +17 more
semanticscholar   +1 more source

Validation of a binding site on the SORLA‐retromer complex that augments endosomal recycling: Implications for a novel class of AD drugs [PDF]

Alzheimers Dement
Genetic studies have established that loss of function SORL1 gene variants are associated with Alzheimer’s disease (AD). SORL1 encodes an endosomal trafficking receptor, SORLA, which regulates endosomal protein recycling through its interaction with the ...
Merchant K, Andersen O, Lefker B, Withka J, Small S, Petsko G, Klein J, Armstrong R.   +7 more
europepmc   +2 more sources

Parkin mediates the ubiquitination of VPS35 and modulates retromer-dependent endosomal sorting [PDF]

, 2018
Erin T. Williams, Liliane Glauser, Elpida Tsika, Haisong Jiang, Md. Shariful Islam, Darren J. Moore   +5 more
openalex   +1 more source

The possible impact of sortilin in reducing HBsAg expression in chronic hepatitis B [PDF]

, 2016
Hepatitis B virus (HBV) infection is a major global health problem. Chronically infected people are at risk for progressive hepatic fibrosis and consequent cirrhosis.
Besharat, S., Darvishi, Z., Katoonizadeh, A., Mohamadkhani, A., Moossavi, S., Poustchi, H., Roshandel, G.   +6 more
core  

EhVps35, a retromer component, is a key factor in secretion, motility, and tissue invasion by Entamoeba histolytica

Frontiers in Cellular and Infection Microbiology
In humans and Drosophila melanogaster, the functional convergence of the endosomal sorting complex required for transport (ESCRT) machinery that is in charge of selecting ubiquitinated proteins for sorting into multivesicular bodies, and the retromer ...
Joselin Díaz-Valdez, R. Javier‐Reyna, Ausencio Galindo, L. Salazar-Villatoro, S. Montaño, Esther Orozco   +5 more
semanticscholar   +1 more source

Decision letter for "An update on cellular and molecular determinants of Parkinson's disease with emphasis on the role of the retromer complex"

, 2020

openalex   +1 more source

Retromer and TBC1D5 maintain late endosomal RAB7 domains to enable amino acid–induced mTORC1 signaling [PDF]

, 2019
Arunas Kvainickas, Heike Nägele, Wenjing Qi, Ladislav Dokládal, Ana Jimenez‐Orgaz, Luca Stehl, Dipak Gangurde, Qian Zhao, Zehan Hu, Jörn Dengjel, Claudio De Virgilio, Ralf Baumeister, Florian Steinberg   +12 more
openalex   +1 more source

OXR1 maintains the retromer to delay brain aging under dietary restriction [PDF]

, 2022
Pankaj Kapahi, Kenneth A. Wilson, Sudipta Bar, Eric B. Dammer, Brian A. Hodge, Enrique M. Carrera, Tyler Hilsabeck, Joanna Bons, George Brownridge, Jennifer Beck, Jacob Rose, Melia Granath-Panelo, Christopher S. Nelson, Alexandra Afenjar, Geetanjali Chawla, Rachel B. Brem, Philippe M. Campeau, Hugo J. Bellen, Birgit Schilling, Nicholas T. Seyfried, Lisa Ellerby   +20 more
openalex   +1 more source

Plant Retromer, Localized to the Prevacuolar Compartment and Microvesicles inArabidopsis, May Interact with Vacuolar Sorting Receptors [PDF]

, 2006
Peter Oliviusson, Oliver Heinzerling, Stefan Hillmer, Giselbert Hinz, Yu Chung Tse, Liwen Jiang, David G. Robinson   +6 more
openalex   +1 more source