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Retromer and sorting nexins in development
Frontiers in Bioscience, 2007Trafficking and signaling processes involve common molecular components. The machinery that controls intracellular trafficking is vital in ensuring that signaling mechanisms take place correctly. An illustrative example of this relationship is the sustained signaling of endocytosed membrane receptors, such as receptor Tyr kinases and G-protein coupled ...
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Retromer-Mediated Protein Sorting and Vesicular Trafficking
Journal of Genetics and Genomics, 2016Retromer is an evolutionarily conserved multimeric protein complex that mediates intracellular transport of various vesicular cargoes and functions in a wide variety of cellular processes including polarized trafficking, developmental signaling and lysosome biogenesis.
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