Results 111 to 120 of about 7,439,285 (173)

Molecular basis for the assembly of the Vps5-Vps17 SNX-BAR proteins with Retromer

Nature Communications
Retromer mediates endosomal retrieval of transmembrane proteins in all eukaryotes and was first discovered in yeast in complex with the Vps5 and Vps17 sorting nexins (SNXs).
Kai-En Chen, Vikas A. Tillu, Navin Gopaldass, Sudeshna Roy Chowdhury, Natalya Leneva, Oleksiy Kovtun, Juanfang Ruan, Qian Guo, Nicholas Ariotti, Andreas Mayer, Brett M. Collins   +10 more
doaj   +1 more source

Dysregulation of SNX1-retromer axis in pharmacogenetic models of Parkinson’s disease

Cell Death Discovery
Since the identification of vacuolar protein sorting (VPS) 35, as a causative molecule for familial Parkinson’s disease (PD), retromer-mediated endosomal machinery has been a rising factor in the pathogenesis of the disease.
Shun Yoshida, Takafumi Hasegawa, Takaaki Nakamura, Kazuki Sato, Naoto Sugeno, Shun Ishiyama, Kiyotoshi Sekiguchi, Muneshige Tobita, Atsushi Takeda, Masashi Aoki   +9 more
doaj   +1 more source

Contrasting Retromer with a Newly Described Retriever in Arabidopsis thaliana

Plants
The tight regulation of protein composition within the plasma membranes of plant cells is crucial for the proper development of plants and for their ability to respond to a changing environment.
Connor D. Lewis, Mary L. Tierney
doaj   +1 more source

Role of the AP-5 adaptor protein complex in late endosome-to-Golgi retrieval.

PLoS Biology, 2018
The AP-5 adaptor protein complex is presumed to function in membrane traffic, but so far nothing is known about its pathway or its cargo. We have used CRISPR-Cas9 to knock out the AP-5 ζ subunit gene, AP5Z1, in HeLa cells, and then analysed the phenotype
Jennifer Hirst, Daniel N Itzhak, Robin Antrobus, Georg H H Borner, Margaret S Robinson   +4 more
doaj   +1 more source

Correction to “From Mitochondria to Immunity: The Emerging Roles of Mitochondria‐Derived Vesicles and Small Extracellular Vesicles in Cellular Communication and Disease”

Journal of Extracellular Vesicles, Volume 14, Issue 12, December 2025.
wiley   +1 more source

Assembly and solution structure of the retromer complex [PDF]

Acta Crystallographica Section A Foundations of Crystallography, 2011
S. Norwood, D. Shaw, N. Cowieson, J. Swarbrick, B. Collins   +4 more
openaire   +1 more source

Enhancing Retromer Complex Stability Ameliorates Synaptic Dysfunction in a Mouse Model of Alzheimer’s Disease

bioRxiv
David Ramonet, Anna Daerr, M. Hallbeck
semanticscholar   +1 more source

VPS35-Retromer: Multifunctional Roles in Various Biological Processes – A Focus on Neurodegenerative Diseases and Cancer

Journal of Inflammation Research
Xiaoyang Fan, Yuqi Xie, Sitong Cao, Li Zhu, Xueting Wang Institute of Special Environmental Medicine, Co-Innovation Center of Neuroregeneration, Nantong University, Nantong, People’s Republic of ChinaCorrespondence: Xueting Wang; Li Zhu, Institute of ...
Fan X, Xie Y, Cao S, Zhu L, Wang X
doaj  

The role of the retromer complex in receptor trafficking

, 2010
Contains fulltext : 77567.pdf (Publisher’s version ) (Open Access)
openaire   +1 more source

VPS29–VPS35 intermediate of retromer is stable and may be involved in the retromer complex assembly process

VPS29–VPS35 intermediate of retromer is stable and may be involved in the retromer complex assembly process
2014年度
openaire