Results 141 to 150 of about 7,439,285 (173)
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Journal of Neuroscience Research, 2020
Parkinson's disease (PD) is a highly prevalent neurodegenerative condition. The disease involves the progressive degeneration of dopaminergic neurons located in the substantia nigra pars compacta.
Vania Macías‐Calvio +2 more
semanticscholar +1 more source
Parkinson's disease (PD) is a highly prevalent neurodegenerative condition. The disease involves the progressive degeneration of dopaminergic neurons located in the substantia nigra pars compacta.
Vania Macías‐Calvio +2 more
semanticscholar +1 more source
Model‐guided microarray implicates the retromer complex in Alzheimer's disease
Annals of Neurology, 2005AbstractAlthough, in principle, gene expression profiling is well suited to isolate pathogenic molecules associated with Alzheimer's disease (AD), techniques such as microarray present unique analytic challenges when applied to disorders of the brain. Here, we addressed these challenges by first constructing a spatiotemporal model, predicting a priori ...
Scott A, Small +8 more
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Biochimica et Biophysica Acta - General Subjects, 2020
Background Intracellular protein trafficking is crucial for survival of cell and proper functioning of the organelles; however, these pathways are not well studied in the malaria parasite. Its unique cellular architecture and organellar composition raise
A. A. Siddiqui +11 more
semanticscholar +1 more source
Background Intracellular protein trafficking is crucial for survival of cell and proper functioning of the organelles; however, these pathways are not well studied in the malaria parasite. Its unique cellular architecture and organellar composition raise
A. A. Siddiqui +11 more
semanticscholar +1 more source
Implication of mouse Vps26b–Vps29–Vps35 retromer complex in sortilin trafficking
Biochemical and Biophysical Research Communications, 2010The retromer complex, which mediates retrograde transport from endosomes to the trans-Golgi network, is a heteropentameric complex that contains a multifunctional cargo recognition heterotrimer consisted of the vacuolar protein sorting (Vps) subunits Vps26, Vps29, and Vps35. In mammals, there are two different isoforms of Vps26, Vps26a and Vps26b, that
Ekyune, Kim +11 more
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New Phytologist
The retromer complex is a conserved sorting machinery that maintains cellular protein homeostasis by transporting vesicles containing cargo proteins to defined destinations. It is known to sort proteins at the vacuole membranes for retrograde trafficking,
Xin Chen +11 more
semanticscholar +1 more source
The retromer complex is a conserved sorting machinery that maintains cellular protein homeostasis by transporting vesicles containing cargo proteins to defined destinations. It is known to sort proteins at the vacuole membranes for retrograde trafficking,
Xin Chen +11 more
semanticscholar +1 more source
, 2020
Hydroxyapatite nanoparticles are utilized extensively in the era of nanotechnology to deliver various drugs to the right area. However, the molecular mechanism behind the transportation of these nanoparticles and its effect on the development and ...
Swetapadma Sahu, M. Mishra
semanticscholar +1 more source
Hydroxyapatite nanoparticles are utilized extensively in the era of nanotechnology to deliver various drugs to the right area. However, the molecular mechanism behind the transportation of these nanoparticles and its effect on the development and ...
Swetapadma Sahu, M. Mishra
semanticscholar +1 more source
Integrative oncology: Addressing the global challenges of cancer prevention and treatment
Ca-A Cancer Journal for Clinicians, 2022Jun J Mao,, Msce +2 more
exaly
Characterization of the retromer complex of proteins in gastric parietal cells
2013Gastric acid secretion involves the regulated recycling of the H, K-ATPase to and from the apical membrane of parietal cells. All of the steps in the regulated recycling of the H,K-ATPase should involve protein trafficking machinery. Based upon preliminary mass spectrometric analysis of isolated, H,K-ATPase-rich gastric microsomes, subunits of the ...
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