Results 71 to 80 of about 2,021,769 (367)

Prediabetes is associated with a higher serum neurofilament light chain level in adolescents

Frontiers in Endocrinology, 2023
ObjectiveSerum neurofilament light chain (sNfL) level, which is a biomarker indicative of neuroaxonal damage and cognitive impairment, has been reported in several neurological diseases.
Zheng Chen, Lan-Ping Wu, Tuo-Chao Peng
doaj   +1 more source

Perinatal outcomes of frequent attendance in midwifery care in the Netherlands: a retrospective cohort study [PDF]

, 2020
Background Over the last decade, a trend towards high utilisation of primary maternity care was observed in high-income countries. There is limited research with contradictory results regarding frequent attendance (FA) and perinatal outcomes in midwifery
Feijen-de Jong, Esther I., Gitsels, Lisanne A., Gitsels-van Der Wal, Janneke T., Hooker, Angelo, Martin, Linda, Scholing, Paula   +5 more
core   +3 more sources

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Factors associated with deaths by tuberculosis in the state of Mato Grosso, 2011-2020: retrospective cohort study [PDF]

Epidemiologia e Serviços de Saúde
Objective: To investigate factors associated with tuberculosis deaths in Mato Grosso state, Brazil, from 2011 to 2020. Methods: Retrospective cohort study with data obtained from the Notifiable Health Conditions Information System and the Mortality ...
Vanessa da Silva Lopes, Rodrigo de Macedo Couto, Alexandre Peron da Luz, Pãmela Rodrigues de Souza Silva, Jaqueline Costa Lima   +4 more
doaj   +1 more source

Clinical Outcomes After Four-Level Anterior Cervical Discectomy and Fusion. [PDF]

, 2018
Study Design: Retrospective cohort study. Objectives: Anterior cervical discectomy and fusion (ACDF) demonstrates reliable improvement in neurologic symptoms associated with anterior compression of the cervical spine.
Hilibrand, Alan S, Hollern, Douglas A, Kepler, Christopher K, Kreitz, Tyler M, Padegimas, Eric M., Schroeder, Gregory D., Vaccaro, MD, PhD, Alexander   +6 more
core   +2 more sources

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Accurate and Generalizable Quantitative Scoring of Liver Steatosis from Ultrasound Images via Scalable Deep Learning [PDF]

arXiv, 2021
Background & Aims: Hepatic steatosis is a major cause of chronic liver disease. 2D ultrasound is the most widely used non-invasive tool for screening and monitoring, but associated diagnoses are highly subjective. We developed a scalable deep learning (DL) algorithm for quantitative scoring of liver steatosis from 2D ultrasound images.
arxiv  

A functional movement screen profile of an Australian state police force: A retrospective cohort study [PDF]

, 2016
BACKGROUND: Police officers are required to perform dynamic movements in unpredictable environments, the results of which can lead to injury. Early identification of poor movement patterns of a police population, and potential sub groups within this ...
Hinton, Ben, Orr, Robin Marc, Pope, Rodney, Stierli, Michael   +3 more
core   +2 more sources

MET and NF2 alterations confer primary and early resistance to first‐line alectinib treatment in ALK‐positive non‐small‐cell lung cancer

Molecular Oncology, EarlyView.
Alectinib resistance in ALK+ NSCLC depends on treatment sequence and EML4‐ALK variants. Variant 1 exhibited off‐target resistance after first‐line treatment, while variant 3 and later lines favored on‐target mutations. Early resistance involved off‐target alterations, like MET and NF2, while on‐target mutations emerged with prolonged therapy.
Jie Hu, Ning Ding, Xiaobo Xu, Yedan Chen, Yong Zhang, Jingwen Liu, Jiebai Zhou, Hairong Bao, Donghui Zhang, Yijun Song, Yang Shao, Yuanlin Song   +11 more
wiley   +1 more source

Incremental Value and Interpretability of Radiomics Features of Both Lung and Epicardial Adipose Tissue for Detecting the Severity of COVID-19 Infection [PDF]

arXiv, 2023
Epicardial adipose tissue (EAT) is known for its pro-inflammatory properties and association with Coronavirus Disease 2019 (COVID-19) severity. However, current EAT segmentation methods do not consider positional information. Additionally, the detection of COVID-19 severity lacks consideration for EAT radiomics features, which limits interpretability ...
arxiv