Results 101 to 110 of about 50,812 (253)
MTV sings jubilation for telomere biology in Drosophila
Fly, 2018 Telomere protects the ends of linear chromosomes. Telomere dysfunction fuels genome instability that can lead to diseases such as cancer. For over 30 years, Drosophila has fascinated the field as the only major model organism that does not rely on the ...
Lin Cheng, Ming Cui, Yikang S. Rong
doaj +1 more source
Understanding extracellular vesicles in antiaging
Periodontology 2000, EarlyView.Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad +3 more
wiley +1 more source
Pivotal Impacts of Retrotransposon Based Invasive RNAs on Evolution
Frontiers in Microbiology, 2017 RNAs have long been described as the mediators of gene expression; they play a vital role in the structure and function of cellular complexes. Although the role of RNAs in the prokaryotes is mainly confined to these basic functions, the effects of these ...
Laleh Habibi, Hamzeh Salmani
doaj +1 more source
Retrotransposon and retrogene insertions leading to false positive calls.
, 2012 A) Retrotransposon insertion to a different chromosome leading to a false translocation call, B) Retrotransposon insertion to the same chromosome as the original leading to a false deletion call, C) Reverse transcribed intronless gene (retrogene ...
Cory R. Lindsay (123928) +6 more
core +1 more source
Streamlining Diagnosis of Bardet–Biedl Syndrome: New Diagnostic Algorithm With Updated Criteria
American Journal of Medical Genetics Part A, Volume 200, Issue 10, Page 2181-2198, October 2026.ABSTRACT Considerable advances have been made in our understanding of Bardet–Biedl syndrome (BBS), particularly in its core clinical features and molecular genetics, warranting an update to the existing diagnostic criteria framework. Using a rigorous, evidence‐based, and consensus‐driven process, a multidisciplinary group of international experts and ...
Jeremy J. Pomeroy +16 more
wiley +1 more source
Genome organization of retroviruses and Ty1 retrotransposon.
, 2020 (A) Schematic representations of retroviral and Ty1 retrotransposon genomes are shown. (B) Proteins translated from gag and gag-pol ORFs are shown. Red dashed lines indicate polyprotein processing by Ty1 PR.
Tibor Nagy (425445) +4 more
core +1 more source
Annals of Neurology, Volume 100, Issue 4, Page 751-767, October 2026.Objective Initially described in 1976, X‐linked dystonia parkinsonism (XDP) is a neurodegenerative disease that can be characterized by the presentation of dystonia and parkinsonism symptoms. Although this disease bears some resemblance to other neurodegenerative diseases in terms of symptomatology, the pathological signature of XDP is still unclear ...
Adelie Y.S. Tan +19 more
wiley +1 more source
Location of retrotransposon eQTL within gene.
, 2013 Polymorphic retrotransposons that were significantly correlated with differential gene expression (see table 7) are presented here. Retrotransposon: Family or subfamily, where known, of the polymorphic transposon.
Sara Linker (222781) +1 more
core +1 more source
The Tnt1 Retrotransposon Escapes Silencing in Tobacco, Its Natural Host [PDF]
, 2012 Retrotransposons' high capacity for mutagenesis is a threat that genomes need to control tightly. Transcriptional gene silencing is a general and highly effective control of retrotransposon expression.
Espinas, L +5 more
core +1 more source
Environmental Toxicology, Volume 41, Issue 10, Page 1105-1118, October 2026.ABSTRACT Given the inevitability of human and animal exposure to acrylamide, there is increasing concern regarding its potential health risks. While a number of molecular mechanisms have been proposed, the complexity of acrylamide toxicological pathways and interactions remains incompletely characterized.
Oluwabukola Mary Farodoye +5 more
wiley +1 more source