Results 61 to 70 of about 21,663 (172)

Cryo-electron Microscopy Structure of the Native Prototype Foamy Virus Glycoprotein and Virus Architecture.

open access: yesPLoS Pathogens, 2016
Foamy viruses (FV) belong to the genus Spumavirus, which forms a distinct lineage in the Retroviridae family. Although the infection in natural hosts and zoonotic transmission to humans is asymptomatic, FVs can replicate well in human cells making it an ...
Grégory Effantin   +7 more
doaj   +1 more source

The Journey of in vivo Virus Engineered Dendritic Cells From Bench to Bedside: A Bumpy Road

open access: yesFrontiers in Immunology, 2018
Dendritic cells (DCs) are recognized as highly potent antigen-presenting cells that are able to stimulate cytotoxic T lymphocyte (CTL) responses with antitumor activity.
Cleo Goyvaerts, Karine Breckpot
doaj   +1 more source

HTLV screening and confirmatory testing among blood donors in São Paulo: A cross‐sectional study

open access: yesTransfusion Medicine, EarlyView.
Abstract Introduction Human T‐cell lymphotropic virus types 1 and 2 (HTLV‐1/2) are transfusion‐transmissible retroviruses associated with severe diseases, and blood donor screening is mandatory in Brazil. Increasing HTLV‐related discard rates at our institution prompted this study to determine the prevalence and incidence of HTLV‐1/2 and to investigate
Suzete C. Ferreira   +11 more
wiley   +1 more source

Expanding the Fish‐Brain Invitrome With the Senegalese Sole SsB‐1 Cell Line—A Versatile Model for Neurotropic Virus Research

open access: yesJournal of Fish Diseases, Volume 49, Issue 10, October 2026.
ABSTRACT Cell lines are essential tools for studying animal physiology and immunopathology, reducing the use of live animals and supporting the 3Rs principle of reduction, refinement, and replacement. The Senegalese sole (Solea senegalensis), a relevant species for Spanish aquaculture diversification, lacks established in vitro models. We developed SsB‐
Yulema Valero, Alberto Cuesta
wiley   +1 more source

RNA viral protein structure database: A comprehensive and user‐friendly web database for RNA viral protein structures

open access: yesiMetaOmics, Volume 3, Issue 3, September 2026.
Given the central role of protein structures in RNA virus biology, the RNA viral protein structure database (RVPSD, https://virus.9itsg.net) integrates taxonomic classification, viral nucleotide and protein sequences, functional annotations, and predicted three‐dimensional protein structures.
Qiangzhen Yang   +8 more
wiley   +1 more source

Prevalence of Human T Lymphotropic Virus Type 1 in Pregnant Women: a Narrative Review

open access: yesMedical Laboratory Journal, 2020
Background and Objectives: Human T lymphotropic virus type I (HTLV-I) is a virus of the Retroviridae family, which has infected more than 20 million people around the world. The study aimed to review the prevalence of HTLV infection in pregnant women.    
zeinab nazari   +2 more
doaj  

Defective HIV proviruses: possible involvement in the HIV infection pathogenesis

open access: yesВопросы вирусологии
This review article analyzes information obtained from a literature search on defective HIV genomes (HIV-1, Human Immunodeficiency Virus, Lentivirus, Orthoretrovirinae, Retroviridae). It discusses the origins of defective HIV genomes, their potential for
Marina R. Bobkova
doaj   +1 more source

Extension of the viral ecology in humans using viral profile hidden Markov models. [PDF]

open access: yesPLoS ONE, 2018
When human samples are sequenced, many assembled contigs are "unknown", as conventional alignments find no similarity to known sequences. Hidden Markov models (HMM) exploit the positions of specific nucleotides in protein-encoding codons in various ...
Zurab Bzhalava   +2 more
doaj   +1 more source

Targeting Human Immunodeficiency Virus Integrase Beyond the Active Site: The Discovery and Development of Allosteric Integrase Inhibitors

open access: yesChemMedChem, Volume 21, Issue 16, 27 August 2026.
Human immunodeficiency virus (HIV) allosteric integrase inhibitors (ALLINIs) offer a vital alternative to standard therapies by targeting noncatalytic sites. By inducing aberrant integrase multimerization, they disrupt viral maturation. This review explores their medicinal chemistry evolution, detailing structural insights, structure–activity ...
Francesco Saccoliti   +10 more
wiley   +1 more source

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