Results 51 to 60 of about 17,921 (159)

Characterization of the longitudinal HIV-1 quasispecies evolution in HIV-1 infected individuals co-infected with Mycobacterium tuberculosis [PDF]

, 2010
One of the earliest and most striking observations made about HIV is the extensive genetic variation that the virus has within individual hosts, particularly in the hypervariable regions of the env gene which is divided into 5 variable regions (V1-V5 ...
Leulebirhan, Tsigereda Biru
core  

The interferon-stimulated gene IFITM3 restricts West Nile virus infection and pathogenesis [PDF]

, 2016
The interferon-induced transmembrane protein (IFITM) family of proteins inhibit infection of several different enveloped viruses in cell culture by virtue of their ability to restrict entry and fusion from late endosomes.
Bradbury LE, Chen YX, Ebel GD, Evans SS, Frey M, Omalu BI, Takahashi S   +6 more
core   +2 more sources

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

Small Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source

An in-depth exploration of snake venom-derived molecules for drug discovery in advancing antiviral therapeutics

Heliyon
Snake venom is a cocktail and rich source of various bioactive compounds that have been extensively studied for their potential as pharmaceutical agents due to their diverse chemical structures and wide range of biological activities.
Hicham Hboub, Reda Ben Mrid, Najat Bouchmaa, Naoual Oukkache, Rachid El Fatimy   +4 more
doaj   +1 more source

Unveiling Novel Viral Diversity, Biogeography, and Host Networks in Wildlife Through High‐Throughput Sequencing Data Mining

Advanced Science, Volume 12, Issue 46, December 11, 2025.
Analysis of 57 536 high‐throughput sequencing datasets uncovers a vast, hidden world of viruses in wildlife. The researchers reveal significant geographic and host‐specific patterns of viruses, and their surprising cross‐species transmissions, such as avian flu viruses infecting goats.
Hai Wang, Yafei Meng, Xiaoyuan Chen, Xinyuan Cui, Qian Zuo, Na Han, Xianghui Liang, Xuejuan Shen, Caiwu Li, Desheng Li, Fumin Wang, Liangping He, Rujian Chen, Xingbang Lu, Wenjie You, Aiping Wu, Rui‐Ai Chen, Wu Chen, Chan Ding, Yongyi Shen   +19 more
wiley   +1 more source

Prevalence of inclusion body disease and associated comorbidity in captive collections of boid and pythonid snakes in Belgium [PDF]

, 2020
Inclusion body disease (IBD) is caused by reptarenaviruses and constitutes one of the most notorious viral diseases in snakes. Although central nervous system disease and various other clinical signs have been attributed to IBD in boid and pythonid ...
Hellebuyck, Tom, Leineweber, Christoph, Marschang, Rachel E, Simard, Jules   +3 more
core   +1 more source

Synthesis of Triphosphate Nucleoside Prodrugs: γ‐ProTriPs

Current Protocols, Volume 5, Issue 12, December 2025.
Abstract Although monophosphate nucleoside prodrug approaches have been extensively investigated, leading to the development of several key antiviral and anticancer drugs, less attention has been given to the design of triphosphate prodrugs for the delivery of triphosphorylated nucleotide analogues.
Camille Tisnerat, Fabrizio Pertusati, Michaela Serpi   +2 more
wiley   +1 more source

Serological prevalence of FeLV and FIV in cats in Peninsular Malaysia. [PDF]

, 2011
Feline Leukemia (Fel.V) and Feline Immunodeficiency Virus (FIV) are the two feline retroviruses that were studied in 65 client-owned cats from eight veterinary centres in selected areas throughout Peninsular Malaysia during a 4-week period.
Arshad, Siti Suri, Bande, Faruku, Dhaliwal, Gurmeet Kaur, Sapian, Nurul Ashikin   +3 more
core  

Transmission of pathogens by "Stomoxys flies (Diptera, Muscidae): a review [PDF]

, 2013
Les stomoxes sont des vecteurs mécaniques de pathogènes présents dans le sang et les tissus cutanés de leurs hôtes, spécialement le bétail, mais aussi parfois les humains.
Baldacchino, Frédéric, Charoenviriyaphap, Theeraphap, Desoli, Florian, Desquesnes, Marc, Duvallet, Gérard, Muenworn, Vithee   +5 more
core   +2 more sources

Current understanding of lymphoproliferative disease virus in wild turkeys

Wildlife Society Bulletin, Volume 49, Issue S1, December 2025.
Lymphoproliferative disease virus (LPDV) is a retrovirus that can cause a spectrum of disease in wild turkeys (Meleagris gallopavo), from subclinical infection to lymphoid tumors. We reviewed the literature to summarize our current understanding of LPDV, including disease presentation, surveillance, impact on fitness, spatiotemporal distribution, and ...
Chloe C. Goodwin, Andrew B. Allison, Mark G. Ruder, Justin D. Brown, Michael J. Chamberlain, Melanie R. Kunkel, Kevin D. Niedringhaus, Alisia A. W. Weyna, Charlie S. Bahnson, Elizabeth L. Elsmo, M. Kevin Keel, Heather Fenton, Kayla G. Adcock, Rebecca L. Poulson, Nicole M. Nemeth   +14 more
wiley   +1 more source