Results 61 to 70 of about 3,148,432 (179)

HIV-1 Gag Specific IgG Response in Mice Immunized with Vp22-Gag Vaccine Candidate [PDF]

, 2017
Background : Stimulation of Gag-specific CD8+ T-cell response, associated with reduction in viremia, viral replication control, and slow disease progression. Effective CD8+ T cell response is also influenced by CD4+ T cells.
Bekti, H. S. (Heri)
core   +1 more source

The relationship between selenium and viral diseases

Interdisciplinary Medicine, Volume 3, Issue 2, March 2025.
This review describes the application and research progress of selenium in antiviral therapy. Starting from the biological functions of selenium, this paper discusses the association of selenium with a variety of viral diseases and analyzes in depth the antiviral mechanisms of selenium, including its immunomodulatory and antioxidant effects.
Jiali Li, Jia Lai, Yuhui Zeng, Bing Zhu, Yinghua Li   +4 more
wiley   +1 more source

A comprehensive overview on the crosstalk between microRNAs and viral pathogenesis and infection

Medicinal Research Reviews, Volume 45, Issue 2, Page 349-425, March 2025.
Abstract Infections caused by viruses as the smallest infectious agents, pose a major threat to global public health. Viral infections utilize different host mechanisms to facilitate their own propagation and pathogenesis. MicroRNAs (miRNAs), as small noncoding RNA molecules, play important regulatory roles in different diseases, including viral ...
Seyedeh Zahra Bahojb Mahdavi, Asiyeh Jebelli, Parisa Shiri Aghbash, Behzad Baradaran, Mohammad Amini, Fatemeh Oroojalian, Nasser Pouladi, Hossein Bannazadeh Baghi, Miguel de la Guardia, Amir Ali Mokhtarzadeh   +9 more
wiley   +1 more source

Viral Encephalitis: Etiology, Clinical Features, Diagnosis and Management [PDF]

, 2015
8openSergio Ferrari; Antonio Toniolo; Salvatore Monaco; Filippo Luciani; Francesca Cainelli; Andreina Baj; Zelalem Temesgen; Sandro VentoSergio, Ferrari; Toniolo, Antonio; Salvatore, Monaco; Filippo, Luciani; Francesca, Cainelli; Baj, Andreina; Zelalem ...

core   +1 more source

Antiviral Activity of Carbon Dots: Strategies and Mechanisms of Action

Small Structures, Volume 6, Issue 3, March 2025.
Carbon dots are capable to interact with viruses through different mechanisms of action, having an antiviral and virucidal effect: inhibition of viral entry into the cells, disruption of viral replication, and damage of the virion structure. The COVID‐19 pandemic profoundly changes the perception of the impact of viral diseases on society and the ...
Plinio Innocenzi, Davide De Forni, Franco Lori   +2 more
wiley   +1 more source

Conserved presence of G-quadruplex forming sequences in the Long Terminal Repeat Promoter of Lentiviruses [PDF]

, 2017
G-quadruplexes (G4s) are secondary structures of nucleic acids that epigenetically regulate cellular processes. In the human immunodeficiency lentivirus 1 (HIV-1), dynamic G4s are located in the unique viral LTR promoter.
A Ayouba, A Henderson, A Rambaut, AK Todd, AM Fleming, AN Lane, AR Haeusler, B Berkhout, B Zhou, BF Keele, D Piekna-Przybylska, D Qu, D Rhodes, D Sen, DJ Patel, E Tosoni, EA Raiber, F Barre-Sinoussi, F Benachenhou, F Bibollet-Ruche, F Heuverswyn Van, F Turrini, G Biffi, GE Crooks, IT Holder, J Felsenstein, J Norseen, J Qiu, J Song, J Yamaguchi, JE Clements, JF Fisette, JP Taylor, K Tamura, K Tluckova, KA Jones, LA Pereira, M Fry, M Metifiot, M Sala, M Scalabrin, MA Larkin, N Maizels, ND Perkins, NH Campbell, P Fratta, P Ivanov, P Murat, P Sket, R Perrone, R Perrone, R Perrone, R Perrone, RC Edgar, RC Gallo, RJ Gifford, S Amrane, S Artusi, S Artusi, S Balasubramanian, S Bhatia, S Broos, S Burge, S Pohlmann, SE Tong-Starksen, SR Wang, SR Wang, Y Wang   +67 more
core   +1 more source

The design of retroviral vectors used in the CAR‐T products, risk management, and future perspective

MedComm, Volume 6, Issue 2, February 2025.
This article compares gamma retroviral and lentiviral vectors, discussing packaging systems and SIN vector design. It also covers risks of secondary malignancies linked to retroviral vectors and strategies to minimize them. The article explores the regulatory framework, safety monitoring, and future safety improvements for CAR‐T therapy, emphasizing a ...
Huifang Yin, Xuejing Wei
wiley   +1 more source

The role of BST2/tetherin in feline retrovirus infection [PDF]

, 2011
Pathogenic retroviral infections of mammals have induced the evolution of cellular anti-viral restriction factors and have shaped their biological activities.
Dietrich, Isabelle, Hosie, Margaret J., Willett, Brian J.   +2 more
core   +1 more source

Modeling the Interplay Between Viral and Immune Dynamics in HIV: A Review and Mrgsolve Implementation and Exploration

Clinical and Translational Science, Volume 18, Issue 2, February 2025.
ABSTRACT Since its initial discovery, HIV has infected more than 70 million individuals globally, leading to the deaths of 35 million. At present, the annual number of deaths has significantly decreased due to 75% of HIV‐positive individuals being on antiretroviral therapy.
Alberto Vegas Rodriguez, Nieves Velez de Mendizábal, Sandhya Girish, Iñaki F. Trocóniz, Justin S. Feigelman   +4 more
wiley   +1 more source

Viral Live‐Attenuated Vaccines (LAVs): Past and Future Directions

Advanced Science, Volume 12, Issue 3, January 20, 2025.
Live attenuated vaccines represent a delicate equilibrium between virulence and immunogenicity during adaptation. The process of animal adaptation involves artificial selection; therefore, adapted viruses exhibit decreased pathogenicity to their original hosts and increased pathogenicity to their adapted hosts.
Yan‐Dong Tang, Yuming Li, Xue‐Hui Cai, Xin Yin   +3 more
wiley   +1 more source