Results 171 to 180 of about 161,769 (345)

Transcriptional response in larvae of the generalist fruit fly Anastrepha obliqua feeding on three different tropical host plants

open access: yesEntomologia Experimentalis et Applicata, EarlyView.
We investigated the molecular basis of host switching by the phytophagous West Indian fruit fly (A. obliqua). Third‐instar larvae showed differential gene expression according to host plants: red mombin, mango, and carambola. The main gene categories differentially expressed were digestion, detoxification, and gene regulators.
Sandra M. Velasco‐Cuervo   +5 more
wiley   +1 more source

Type I interferon signalling and interferon‐responsive microglia in health and disease

open access: yesThe FEBS Journal, EarlyView.
Recent insights reveal that type I interferon (IFN‐I) signalling plays critical roles in the nervous system beyond antiviral defence. Dysregulated IFN‐I activity is increasingly linked to neurological dysfunction and neurodegeneration, with microglia as central mediators. This review explores the broader impact of IFN‐I signalling on the nervous system
Jose P. Lopez‐Atalaya   +1 more
wiley   +1 more source

Correction of adenosine deaminase deficiency in cultured human T and B cells by retrovirus-mediated gene transfer. [PDF]

open access: green, 1986
Philip W. Kantoff   +9 more
openalex   +1 more source

Mycobacterium avium Subsp. paratuberculosis and Human Endogenous Retrovirus in Italian Patients With Inflammatory Bowel Disease (IBD) and Irritable Bowel Syndrome (IBS)

open access: yesImmunology, EarlyView.
Inflammatory bowel disease (IBD), comprising ulcerative colitis (UC) and Crohn's disease (CD), is a recognised gastrointestinal disorder. Mycobacterium avium subspecies paratuberculosis (MAP) is implicated in IBD pathogenesis. Persistent exposure and active infections by MAP may contribute to the unsilencing of human endogenous retroviruses (HERV ...
Stefano Ruberto   +14 more
wiley   +1 more source

Selectivity and anti‐tumor immune elevation by vascular‐targeted photodynamic therapy of mouse orthotopic bladder cancer model

open access: yesPhotochemistry and Photobiology, EarlyView.
Vascular‐targeted photodynamic therapy (VTP) using the photosensitizer WST11 is a non‐surgical tumor ablation approach. Light activation of WST11 leads to excessive generation of reactive oxygen species, which causes tumor vascular arrest, followed by destruction of tumor blood vessels and tumor necrosis.
Jie Chen   +8 more
wiley   +1 more source

Insertion of a bacterial gene into the mouse germ line using an infectious retrovirus vector.

open access: green, 1985
Dennis Huszar   +6 more
openalex   +1 more source

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