Results 201 to 210 of about 168,869 (309)

Decitabine-Venetoclax Treatment Reactivates Endogenous Retrovirus RNA Signaling in AML Cells and Induces T Cell Activation [PDF]

Kotoko Yamatani, Kaori Saito, Abhishek Maiti, Abdullah Khasawneh, Faith Jessica Paran, Tastuya Suzuki, Toru Okamoto, Kala Hayes, Zhihong Zeng, Courtney D. DiNardo, Michael Andreeff, Marina Konopleva, Yoko Tabe   +12 more
openalex   +1 more source

A new retrovirus packaging cell for gene transfer constructed from amplified long terminal repeat-free chimeric proviral genes [PDF]

, 1992
Yoshiyuki Takahara, K Hamada, David E. Housman   +2 more
openalex   +1 more source

STAT3 SH2 Domain Aspartic Acid 661 Mutations Activate Immune Gene Programs

Journal of Cellular and Molecular Medicine, Volume 30, Issue 1, January 2026.
ABSTRACT The conserved aspartic acid residue D661 within the STAT3 SH2 domain is a recurrent mutational hotspot in hematologic malignancies, including T‐cell large granular lymphocytic leukaemia, myelodysplastic syndromes and acute lymphoblastic leukaemia. To define the functional consequences of distinct STAT3D661 variants, we integrated computational,
Hye Kyung Lee, Gyuhyeok Cho, Jichun Chen, Aaron B. Schultz, Sung‐Gwon Lee, Chengyu Liu, Priscilla A. Furth, Neal S. Young, Jungwook Kim, Alejandro Villarino, Lothar Hennighausen   +10 more
wiley   +1 more source

RETREG1/FAM134B-mediated micro-ER-phagy in the retrovirus-SERINC5 arms race. [PDF]

Autophagy Rep
Camilleri JM, Ahmad I, Zhang J, Li S, Zheng YH.   +4 more
europepmc   +1 more source

Kinetics of Fluorescence Expression in Nonhuman Primates Transplanted with GFP Retrovirus-Modified CD34 Cells [PDF]

, 2002
Peter Kurre, Julia Morris, Robert G. Andrews, Donald B. Kohn, Hans‐Peter Kiem   +4 more
openalex   +1 more source

HLA‐Knockout: Enabling Allele‐Specific Knockout of HLA Class I Genes for Immunogenic Engineering

HLA, Volume 107, Issue 1, January 2026.
ABSTRACT The interaction between T‐cell receptors (TCRs) and antigenic peptides presented by HLA molecules is fundamental to adaptive immunity. However, the extreme polymorphism of HLA genes poses major challenges for transplantation, antigen discovery, immunotherapy and studies of allele‐specific function.
Connor Mattivi, Shiyu Wang, Longtao Ji, Qian Xiao, Jian Cao   +4 more
wiley   +1 more source

Beyond reverse transcription: molecular mechanisms and emerging paradigms in retroviral replication. [PDF]

FEMS Microbiol Rev
Jehad MA, Ali LM, Pillai VN, Prabhu SG, Mustafa F, Rizvi TA.   +5 more
europepmc   +1 more source

Chimeric Antigen Receptor T‐Cell Therapy: More Than an Anti‐Cancer Drug

HLA, Volume 107, Issue 1, January 2026.
ABSTRACT Initially, chimeric antigen receptor (CAR) T‐cell therapy was developed to eliminate malignant B cells in haematological B‐cell malignancies by targeting CD19 and B‐cell maturation antigen. This approach achieved notable success, resulting in (malignant) B‐cell depletion and inducing clinical remission in cancer patients.
Hannah C. M. Schenk, Ilse Gille, Carolt Arana, Jordi Rovira, Eduard Palou, Fritz Diekmann, Dave L. Roelen, Mirjam H. M. Heemskerk, Sebastiaan Heidt   +8 more
wiley   +1 more source

Metastatic potential of ovine pulmonary adenocarcinoma: a comprehensive assessment of the draining pulmonary lymph nodes. [PDF]

J Vet Diagn Invest
Hodor D, Negoescu A, Pop R, Popa R, Borfalău C, Hașaș AD, Cazan CD, Savage J, Cousens C, Aharoni K, Hilbe M, Rosato G, Dumitru I, Olech M, Bocăneț VI, Cătoi C, Taulescu M, Toma C.   +17 more
europepmc   +1 more source

Insertion of a bacterial gene into the mouse germ line using an infectious retrovirus vector.

, 1985
Dennis Huszar, Rudi Balling, Rashmi Kothary, Maria Cristina Magli, Nobumichi Hozumi, Janet Rossant, Alan Bernstein   +6 more
openalex   +2 more sources