The Genetic Blueprint of Obesity: From Pathogenesis to Novel Therapies
ABSTRACT Obesity is a chronic metabolic disease characterized by disturbances in energy homeostasis, leading to excessive fat accumulation. The pathogenesis of the disease is shaped by a complex interplay of genetic, epigenetic, biological, psychological, and environmental factors.
Gašper Tonin+6 more
wiley +1 more source
Vascular‐targeted photodynamic therapy (VTP) using the photosensitizer WST11 is a non‐surgical tumor ablation approach. Light activation of WST11 leads to excessive generation of reactive oxygen species, which causes tumor vascular arrest, followed by destruction of tumor blood vessels and tumor necrosis.
Jie Chen+8 more
wiley +1 more source
Adaptive evolution of koala retrovirus transcription silencing and what it means for conservation. [PDF]
Chappell KJ+3 more
europepmc +1 more source
GENETIC MANIPULATION OF HUMAN HEMATOPOIETIC CELLS WITH RETROVIRUS VECTORS [PDF]
Zeev Estrov+2 more
openalex +1 more source
Factors determining chromosomal localization of transposable elements in plants
We review transposon chromosomal niches, and the functional consequences of their specific chromosomal localization in plants. Abstract Transposable elements (TEs) constitute a significant part of plant genomes and shape their genomic landscape. While some TEs are ubiquitously dispersed, other elements specifically occupy discrete genomic loci.
E. Kejnovsky+3 more
wiley +1 more source
Construction of stable packaging cell lines for large-scale industrial BaEV-enveloped retroviral vector production. [PDF]
Zhao L+13 more
europepmc +1 more source
Nucleic acid structure and expression of the human AIDS/lymphadenopathy retrovirus [PDF]
Mark A. Muesing+5 more
openalex +1 more source
Phylogenomics Unveils the Complex Evolution of Retroviruses in Birds. [PDF]
He Q, Liu Q, Gong Z, Han GZ.
europepmc +1 more source
Processed enzymatically active protease (p15gag) of avian retrovirus obtained in an E. coli system expressing a recombinant precursor (Pr25lac‐Δgag) [PDF]
Juraj Sedláček+6 more
openalex +1 more source