Results 201 to 210 of about 134,326 (264)
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Unraveling retrovirus integration
Cell, 1990Compared with prokaryotic mobile DNA elements, the study of recombination mechanisms and proteins involved in the integration of vertebrate retroviruses is in its infancy. Genetic and biochemical studies have provided critical insights into defining the role in integration of both the retrovirus-encoded DNA endonuclease and the cisacting long terminal ...
D P, Grandgenett, S R, Mumm
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Journal of Zoo and Wildlife Medicine, 2016
Koala retrovirus (KoRV) is a gammaretrovirus that has been identified in both captive and free-ranging koalas ( Phascolarctos cinereus ) with variable geographic distribution in Australia. KoRV is capable of both exogenous and endogenous transmission, which provides an interesting research platform for scientists to study active retrovirus ...
Matthew E, Kinney, Geoffrey W, Pye
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Koala retrovirus (KoRV) is a gammaretrovirus that has been identified in both captive and free-ranging koalas ( Phascolarctos cinereus ) with variable geographic distribution in Australia. KoRV is capable of both exogenous and endogenous transmission, which provides an interesting research platform for scientists to study active retrovirus ...
Matthew E, Kinney, Geoffrey W, Pye
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Fluidity of a retrovirus genome
Journal of Virology, 1984Comparison of the genomic sequences of the Friend spleen focus-forming virus with other murine retroviral sequences indicated that the spleen focus-forming virus was derived from at least three retroviruses. The 5' end of the virus, from the primer binding site through most of gag, was derived from AKV.
S P, Clark, T W, Mak
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Retrovirus insertion into herpesviruses
Trends in Microbiology, 1994Recent studies have indicated that retroviruses can integrate into and mutate the genomes of herpesviruses during co-infection. This interaction has the potential to change the host range and pathogenicity of both viruses and result in novel infectious agents and diseases.
R J, Isfort, R, Witter, H J, Kung
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Natural Computing, 2005
A practical intra-cellular biomolecular computer should work inside living cells without damaging them. The retrovirus-based biomolecular computer has been designed, by mimicking the natural processes of living cells, to enable the creation of a practical intra-cellular computer.
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A practical intra-cellular biomolecular computer should work inside living cells without damaging them. The retrovirus-based biomolecular computer has been designed, by mimicking the natural processes of living cells, to enable the creation of a practical intra-cellular computer.
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Oligomerization of Retrovirus Integrases
2018Integration of the reverse-transcribed viral cDNA into the host's genome is a critical step in the lifecycle of all retroviruses. Retrovirus integration is carried out by integrase (IN), a virus-encoded enzyme that forms an oligomeric 'intasome' complex with both ends of the linear viral DNA to catalyze their concerted insertions into the backbones of ...
Duane P, Grandgenett, Hideki, Aihara
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Retrovirus in multiple sclerosis
Acta Neurologica Scandinavica, 1989Presence of cytopathic effect and enzyme reverse transcriptase in cultures of peripheral blood mononuclear cells is described in 2 of 15 patients with multiple sclerosis and none of healthy controls. These findings might indicate: the presence of a new human retrovirus in these individuals, despite the low detection rate, and the shortcomings inherent ...
S, Kam-Hansen +3 more
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Retrovirus Envelope Glycoproteins
1990The envelope glycoprotein complex of replication competent retroviruses is comprised of two polypeptides, an external, glycosylated, hydrophilic polypeptide (SU) and a membrane-spanning protein (TM), that form a knob or knobbed spike on the surface of the virion.
E, Hunter, R, Swanstrom
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Herpesvirus / Retrovirus Chimeric Vectors
Current Gene Therapy, 2004Over the years, the design of HSV-1 based vectors has developed from different types of replicative-defective and replication-conditioned recombinant viruses to plasmid based amplicon vectors. More recently hybrid or chimeric vectors have incorporated desired elements of different viruses to increase the efficacy of gene delivery in vitro and in vivo ...
EPSTEIN AL, MANSERVIGI, Roberto
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A Transmissible Human Endogenous Retrovirus
AIDS Research and Human Retroviruses, 2002The transmissibility of the human endogenous retrovirus HERV-H/RGH-2 was investigated by marker rescue: intraspecies transmission of HERV-H/RGH-2 retrovirus particles was attempted by cocultivation of virion-producing, long-term cell cultures spontaneously formed from peripheral blood mononuclear cells from several multiple sclerosis patient cultures ...
Christensen, T. +3 more
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