Results 101 to 110 of about 124,737 (275)
Co-option of endogenous retroviruses through genetic escape from TRIM28 repression [PDF]
, 2023 Rocio Enriquez-Gasca +8 more
openalex +1 more source
iLABMED, EarlyView.We identified FOXA2 as a key regulator of lymph node metastasis in thyroid cancer, which controls cancer cell aggressiveness. FOXA2 knockdown promotes metastasis by enhancing tumor cell migration and, importantly, by inducing T‐cell apoptosis through a CCL2/LCN2‐mediated pathway. Created with BioGDP.com.
Ping Yang +6 more
wiley +1 more source
Precise Therapy Using the Selective Endogenous Encapsidation for Cellular Delivery Vector System
PharmaceuticsInterindividual variability in drug response is a major problem in the prescription of pharmacological treatments. The therapeutic effect of drugs can be influenced by human genes.
Vacis Tatarūnas +2 more
doaj +1 more source
Anti-viral activity of red microalgal polysaccharides against retroviruses
Cancer Cell International, 2002 Red microalgal polysaccharides significantly inhibited the production of retroviruses (murine leukemia virus- MuLV) and cell transformation by murine sarcoma virus(MuSV-124) in cell culture.
Huleihel Mahmoud M +2 more
doaj +1 more source
Role of HIV RNA structure in recombination and speciation: romping in purine A, keeps HTLV away
, 2013 Extreme enrichment of the human immunodeficiency virus (HIV-1) RNA genome for the purine A parallels the mild purine-loading of the RNAs of most organisms.
Forsdyke, Donald R.
core +1 more source
People and Nature, EarlyView.Abstract Understanding the frequency and socio‐ecological drivers of contacts between humans and non‐human primates (NHPs) is crucial for enhancing coexistence that favours NHP conservation, while limiting negative consequences such as aggressions and cross‐species disease transmission.
Cristina Caparrós‐Vallcorba +3 more
wiley +1 more source
Viroids-First—A Model for Life on Earth, Mars and Exoplanets
Geosciences, 2019 The search for extraterrestrial life, recently fueled by the discovery of exoplanets, requires defined biosignatures. Current biomarkers include those of extremophilic organisms, typically archaea.
Karin Moelling, Felix Broecker
doaj +1 more source
Comparison of the generic neuronal differentiation and neuron subtype specification functions of mammalian achaete-scute and atonal homologs in cultured neural progenitor cells [PDF]
, 2002 In the vertebrate peripheral nervous system, the proneural genes neurogenin 1 and neurogenin 2 (Ngn1 and Ngn2), and Mash1 are required for sensory and autonomic neurogenesis, respectively.
Anderson, David J. +3 more
core
Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing
Small, EarlyView.The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa +4 more
wiley +1 more source
Viruses, 2009 Although polypurine tract (PPT)-primed initiation of plus-strand DNA synthesis in retroviruses and LTR-containing retrotransposons can be accurately duplicated, the molecular details underlying this concerted series of events remain largely unknown ...
Stuart F. J. Le Grice +2 more
doaj +1 more source