Results 11 to 20 of about 124,737 (275)

How Active Are Porcine Endogenous Retroviruses (PERVs)? [PDF]

open access: goldViruses, 2016
Porcine endogenous retroviruses (PERVs) represent a risk factor if porcine cells, tissues, or organs were to be transplanted into human recipients to alleviate the shortage of human transplants; a procedure called xenotransplantation.
Joachim Denner
doaj   +2 more sources

Transcriptome mining reveals diversity and evolution of circulating and endogenous amphibian retroviruses [PDF]

open access: yesRetrovirology
Background The evolutionary history of retroviruses and their impact on vertebrate evolution remains poorly understood, particularly in non-mammalian hosts.
Emma F. Harding   +4 more
doaj   +2 more sources

The Spread of Endogenous Retroviruses in Populations Infected by Exogenous Viruses [PDF]

open access: yesViruses
Retroviruses insert DNA copies of themselves into the chromosomes of their hosts forming proviruses that can synthesize new transmissible viruses.
Hyunjin Park, Paul G. Higgs
doaj   +2 more sources

Larger mammalian body size leads to lower retroviral activity [PDF]

open access: yes, 2014
Retroviruses have been infecting mammals for at least 100 million years, leaving descendants in host genomes known as endogenous retroviruses (ERVs). The abundance of ERVs is partly determined by their mode of replication, but it has also been suggested ...
Belshaw, Robert   +5 more
core   +18 more sources

Vpx enhances innate immune responses independently of SAMHD1 during HIV-1 infection

open access: yesRetrovirology, 2021
Background The genomes of HIV-2 and some SIV strains contain the accessory gene vpx, which carries out several functions during infection, including the downregulation of SAMHD1.
Oya Cingöz   +3 more
doaj   +1 more source

O-22 DIFFERENTIAL MUTATION PATTERN ASSOCIATED WITH HEPATITIS B E ANTIGEN SEROCONVERSION BETWEEN SUBGENOTYPE F1b CLUSTERS: POTENTIAL ROLE IN PATHOGENESIS

open access: yesAnnals of Hepatology, 2023
Introduction and Objectives: Two clusters of the subgenotype F1b (basal and cosmopolitan) have recently been described. The basal cluster has been associated with the early occurrence of hepatocellular carcinoma in chronically infected patients from ...
Micaela Martínez   +4 more
doaj   +1 more source

The large extracellular loop of CD63 interacts with gp41 of HIV-1 and is essential for establishing the virological synapse

open access: yesScientific Reports, 2021
Human immunodeficiency virus type 1 (HIV-1) persists lifelong in infected individuals and has evolved unique strategies in order to evade the immune system. One of these strategies is the direct cell-to-cell spread of HIV-1.
Daniel Ivanusic   +3 more
doaj   +1 more source

Review and Perspectives on the Structure–Function Relationships of the Gag Subunits of Feline Immunodeficiency Virus

open access: yesPathogens, 2021
The Gag polyprotein is implied in the budding as well as the establishment of the supramolecular architecture of infectious retroviral particles. It is also involved in the early phases of the replication of retroviruses by protecting and transporting ...
Mathieu Long   +2 more
doaj   +1 more source

Characterization of HIV-1 Epidemic in Kyrgyzstan

open access: yesFrontiers in Microbiology, 2021
Kyrgyzstan has one of the highest rates of HIV-1 spread in Central Asia. In this study, we used molecular–epidemiological approaches to examine the HIV-1 epidemic in Kyrgyzstan.
Mariya V. Sivay   +16 more
doaj   +1 more source

Spatiotemporal dynamics of HIV-1 CRF63_02A6 sub-epidemic

open access: yesFrontiers in Microbiology, 2022
HIV-1 epidemic in Russia is one of the fastest growing in the world reaching 1.14 million people living with HIV-1 (PLWH) in 2021. Since mid-1990s, the HIV-1 epidemic in Russia has started to grow substantially due to the multiple HIV-1 outbreaks among ...
Mariya V. Sivay   +19 more
doaj   +1 more source

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