Results 11 to 20 of about 84,233 (235)

Endogenous retroviruses of non-avian/mammalian vertebrates illuminate diversity and deep history of retroviruses. [PDF]

open access: yesPLoS Pathogens, 2018
The deep history and early diversification of retroviruses remains elusive, largely because few retroviruses have been characterized in vertebrates other than mammals and birds.
Xiaoyu Xu   +3 more
doaj   +2 more sources

Maturation of retroviruses [PDF]

open access: yesCurrent Opinion in Virology, 2019
During retrovirus maturation, cleavage of the precursor structural Gag polyprotein by the viral protease induces architectural rearrangement of the virus particle from an immature into a mature, infectious form. The structural rearrangement encapsidates the viral RNA genome in a fullerene capsid, producing a diffusible viral core that can initiate ...
Owen, Pornillos   +1 more
openaire   +3 more sources

RETRACTED ARTICLE: Antibodies against endogenous retroviruses promote lung cancer immunotherapy

open access: yesNature, 2023
In lung adenocarcinoma, antibodies against endogenous retroviruses promote anti-tumour activity, and expression of endogenous retroviruses can predict outcomes of immunotherapy.
K. Ng   +332 more
semanticscholar   +1 more source

Resurrection of endogenous retroviruses during aging reinforces senescence

open access: yesbioRxiv, 2021
Whether and how certain transposable elements with viral origins, such as endogenous retroviruses (ERVs) dormant in our genomes, can become awakened and contribute to the aging process are largely unknown.
Xiaoqian Liu   +32 more
semanticscholar   +1 more source

Endogenous retroviruses promote homeostatic and inflammatory responses to the microbiota

open access: yesCell, 2021
Summary The microbiota plays a fundamental role in regulating host immunity. However, the processes involved in the initiation and regulation of immunity to the microbiota remain largely unknown.
Djalma S. Lima-Junior   +19 more
semanticscholar   +1 more source

Endogenous retroviruses in the origins and treatment of cancer

open access: yesGenome Biology, 2021
Endogenous retroviruses (ERVs) are emerging as promising therapeutic targets in cancer. As remnants of ancient retroviral infections, ERV-derived regulatory elements coordinate expression from gene networks, including those underpinning embryogenesis and
N. Jansz, G. Faulkner
semanticscholar   +1 more source

Sensing Retroviruses [PDF]

open access: yesImmunity, 2011
Sensing pathogens is an essential first step in the initiation of a host response to infection. In this issue of Immunity, Kane et al. (2011) used mouse models to demonstrate that Toll-like receptor 7 is required for the generation of an antibody response to infection by retroviruses.
Liberatore, Rachel A.   +1 more
openaire   +2 more sources

Endogenous retroviruses [PDF]

open access: yesCurrent Biology, 2015
Endogenous retroviruses are integral features of vertebrate genomes. Here, Hayward and Katzourakis offer a glimpse into the fascinating world of these mysterious partners in our evolution.
Hayward, Alexander, Katzourakis, Aris
openaire   +2 more sources

Influence of Different Glycoproteins and of the Virion Core on SERINC5 Antiviral Activity

open access: yesViruses, 2021
Host plasma membrane protein SERINC5 is incorporated into budding retrovirus particles where it blocks subsequent entry into susceptible target cells.
William E. Diehl   +6 more
doaj   +1 more source

Complement Proteins as Soluble Pattern Recognition Receptors for Pathogenic Viruses

open access: yesViruses, 2021
The complement system represents a crucial part of innate immunity. It contains a diverse range of soluble activators, membrane-bound receptors, and regulators.
Valarmathy Murugaiah   +5 more
doaj   +1 more source

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