Results 21 to 30 of about 120,627 (303)
Viruses, 2014 The HERV-K(HML-2) family contains the most recently integrated and best preserved endogenized proviral sequences in the human genome. All known elements have nevertheless been subjected to mutations or deletions that render expressed particles non ...
Oliver Hohn +5 more
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It’s the Little Things (in Viral RNA)
mBio, 2020 Chemical modifications of viral RNA are an integral part of the viral life cycle and are present in most classes of viruses. To date, more than 170 RNA modifications have been discovered in all types of cellular RNA.
Jiří František Potužník +1 more
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Influence of Different Glycoproteins and of the Virion Core on SERINC5 Antiviral Activity
Viruses, 2021 Host plasma membrane protein SERINC5 is incorporated into budding retrovirus particles where it blocks subsequent entry into susceptible target cells.
William E. Diehl +6 more
doaj +1 more source
The innate immune factor RPRD2/REAF and its role in the Lv2 restriction of HIV
mBio, 2023 Intracellular innate immunity involves co-evolved antiviral restriction factors that specifically inhibit infecting viruses. Studying these restrictions has increased our understanding of viral replication, host-pathogen interactions, and pathogenesis ...
Kathryn A. Jackson-Jones +2 more
doaj +1 more source
Immunity, 2011 Sensing pathogens is an essential first step in the initiation of a host response to infection. In this issue of Immunity, Kane et al. (2011) used mouse models to demonstrate that Toll-like receptor 7 is required for the generation of an antibody response to infection by retroviruses.
Liberatore, Rachel A. +1 more
openaire +2 more sources
Leukocytosis and Expression of Bovine Leukemia Virus microRNAs in Cattle
Frontiers in Veterinary Science, 2020 Bovine Leukemia Virus (BLV) is an established model for studying retroviral infections, in particular the infection by the human T-cell leukemia type 1 (HTLV-1) virus.
Gleb Yu. Kosovsky +6 more
doaj +1 more source
APOBEC3 family proteins as drivers of virus evolution
Frontiers in Virology, 2023 The apolipoprotein B mRNA editing enzyme catalytic polypeptide-like (APOBEC) family consists of cytosine deaminases implicated in diverse and important biological functions.
Michael Jonathan +2 more
doaj +1 more source
Retroviruses and the Placenta [PDF]
Current Biology, 2012 Retroviruses are often expressed in the placenta. Placental expression probably evolved to facilitate retroviral transmission from mother to offspring and from offspring to mother. In the process, the placenta became a site where retroviral genes were 'domesticated' to serve adaptive functions in the host, including the manipulation of maternal ...
openaire +4 more sources
Is HIV-1 RNA dimerization a prerequisite for packaging? Yes, no, probably? [PDF]
, 2004 During virus assembly, all retroviruses specifically encapsidate two copies of full-length viral genomic RNA in the form of a non-covalently linked RNA dimer.
Liang, Chen +2 more
core +3 more sources
Retroviruses and Autoimmunity.
Internal Medicine, 2001 The investigation of human retroviruses has shown dramatic progress since the discovery of human immunodeficiency virus (HIV). These studies have also contributed to the exploration of the role of retroviruses, including endogenous retroviruses, in the induction of autoimmune diseases such as systemic lupus erythematosus (SLE).
Hiroshi Hashimoto +4 more
openaire +4 more sources