Results 21 to 30 of about 124,737 (275)
Vaccination directed against the human endogenous retrovirus-K envelope protein inhibits tumor growth in a murine model system [PDF]
, 2013 Human endogenous retrovirus (HERV) genomes are chromosomally integrated in all cells of an individual. They are normally transcriptionally silenced and transmitted only vertically. Enhanced expression of HERV-K accompanied by the emergence of anti-HERV-K-
Büchner, Sarah M. +6 more
core +11 more sources
A Missing Link between Retrotransposons and Retroviruses
mBio, 2022 The origin and deep evolution of retroviruses remain largely unclear. It has been proposed that retroviruses might have originated from a Ty3/Gypsy retrotransposon, but all known Ty3/Gypsy retrotransposons are only distantly related to retroviruses ...
Jianhua Wang, Guan-Zhu Han
doaj +1 more source
Immunity, 2011 Sensing pathogens is an essential first step in the initiation of a host response to infection. In this issue of Immunity, Kane et al. (2011) used mouse models to demonstrate that Toll-like receptor 7 is required for the generation of an antibody response to infection by retroviruses.
Liberatore, Rachel A. +1 more
openaire +2 more sources
Current Biology, 2015 Endogenous retroviruses are integral features of vertebrate genomes. Here, Hayward and Katzourakis offer a glimpse into the fascinating world of these mysterious partners in our evolution.
Hayward, Alexander, Katzourakis, Aris
openaire +2 more sources
Influence of Different Glycoproteins and of the Virion Core on SERINC5 Antiviral Activity
Viruses, 2021 Host plasma membrane protein SERINC5 is incorporated into budding retrovirus particles where it blocks subsequent entry into susceptible target cells.
William E. Diehl +6 more
doaj +1 more source
Complement Proteins as Soluble Pattern Recognition Receptors for Pathogenic Viruses
Viruses, 2021 The complement system represents a crucial part of innate immunity. It contains a diverse range of soluble activators, membrane-bound receptors, and regulators.
Valarmathy Murugaiah +5 more
doaj +1 more source
Structural Analysis of Retrovirus Assembly and Maturation
Viruses, 2021 Retroviruses have a very complex and tightly controlled life cycle which has been studied intensely for decades. After a virus enters the cell, it reverse-transcribes its genome, which is then integrated into the host genome, and subsequently all ...
Anna-Sophia Krebs +2 more
doaj +1 more source
Endogenous retroviruses of non-avian/mammalian vertebrates illuminate diversity and deep history of retroviruses. [PDF]
PLoS Pathogens, 2018 The deep history and early diversification of retroviruses remains elusive, largely because few retroviruses have been characterized in vertebrates other than mammals and birds.
Xiaoyu Xu +3 more
doaj +1 more source
The extraordinary evolutionary history of the reticuloendotheliosis viruses [PDF]
, 2013 The reticuloendotheliosis viruses (REVs) comprise several closely related amphotropic retroviruses isolated from birds. These viruses exhibit several highly unusual characteristics that have not so far been adequately explained, including their extremely
A Katzourakis +95 more
core +3 more sources
Dynein Regulators Are Important for Ecotropic Murine Leukemia Virus Infection [PDF]
, 2016 Indexación: Web of Science.During the early steps of infection, retroviruses must direct the movement of the viral genome into the nucleus to complete their replication cycle.
Arriagada, Gloria +4 more
core +1 more source