Results 31 to 40 of about 124,737 (275)

Highlights from the 24th conference on retroviruses and opportunistic infections, 13-16 February 2017, Seattle, Washington, USA [PDF]

open access: yes, 2017
From the 13th to 16th February 2017, researchers from around the world convened for the 24th annual Conference on Retroviruses and Opportunistic Infections (CROI) at the Washington State Convention Center in Seattle, Washington.
Bhagani, Sanjay   +12 more
core   +5 more sources

Molecular evolution of HIV-1 integrase during the 20 years prior to the first approval of integrase inhibitors

open access: yesVirology Journal, 2017
Background Detailed knowledge of the evolutionary potential of polymorphic sites in a viral protein is important for understanding the development of drug resistance in the presence of an inhibitor. We therefore set out to analyse the molecular evolution
Karolin Meixenberger   +9 more
doaj   +1 more source

CMV-Promoter Driven Codon-Optimized Expression Alters the Assembly Type and Morphology of a Reconstituted HERV-K(HML-2)

open access: yesViruses, 2014
The HERV-K(HML-2) family contains the most recently integrated and best preserved endogenized proviral sequences in the human genome. All known elements have nevertheless been subjected to mutations or deletions that render expressed particles non ...
Oliver Hohn   +5 more
doaj   +1 more source

The innate immune factor RPRD2/REAF and its role in the Lv2 restriction of HIV

open access: yesmBio, 2023
Intracellular innate immunity involves co-evolved antiviral restriction factors that specifically inhibit infecting viruses. Studying these restrictions has increased our understanding of viral replication, host-pathogen interactions, and pathogenesis ...
Kathryn A. Jackson-Jones   +2 more
doaj   +1 more source

Highly Variable Genomic Landscape of Endogenous Retroviruses in the C57BL/6J Inbred Strain, Depending on Individual Mouse, Gender, Organ Type, and Organ Location. [PDF]

open access: yes, 2017
Transposable repetitive elements, named the "TREome," represent ~40% of the mouse genome. We postulate that the germ line genome undergoes temporal and spatial diversification into somatic genomes in conjunction with the TREome activity.
Cho, Kiho   +3 more
core   +2 more sources

Discovery of an endogenous foamy virus in primitive ruminant chevrotains

open access: yesMicrobiology Spectrum, 2023
Foamy viruses (FVs) are a class of complex retroviruses that could lead to persistent infections in specific species. FVs have two evolutionary characteristics: the first is co-evolution with the host, and the second is difficulty going through the ...
Xiaojing Wang, Jie Cui
doaj   +1 more source

Is HIV-1 RNA dimerization a prerequisite for packaging? Yes, no, probably? [PDF]

open access: yes, 2004
During virus assembly, all retroviruses specifically encapsidate two copies of full-length viral genomic RNA in the form of a non-covalently linked RNA dimer.
Liang, Chen   +2 more
core   +3 more sources

Retroviral Infection and Commensal Bacteria Dependently Alter the Metabolomic Profile in a Sterile Organ

open access: yesViruses, 2023
Both viruses and bacteria produce “pathogen associated molecular patterns” that may affect microbial pathogenesis and anti-microbial responses. Additionally, bacteria produce metabolites, while viruses could change the metabolic profiles of the infected ...
Jessica Spring   +6 more
doaj   +1 more source

Human retroviruses

open access: yesBaillière's Clinical Haematology, 1992
It was only in 1980 that the first human retrovirus, HTLV-1, was isolated. Since then, HTLV-2, HIV-1 and HIV-2 have been identified. All four viruses are transmitted with varying efficiency sexually, vertically from mother to infant, and through blood by transfusion or contamination.
Weber, T.   +3 more
openaire   +3 more sources

APOBEC3 family proteins as drivers of virus evolution

open access: yesFrontiers in Virology, 2023
The apolipoprotein B mRNA editing enzyme catalytic polypeptide-like (APOBEC) family consists of cytosine deaminases implicated in diverse and important biological functions.
Michael Jonathan   +2 more
doaj   +1 more source

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