Results 51 to 60 of about 68,205 (163)
The Spread of Endogenous Retroviruses in Populations Infected by Exogenous Viruses
Retroviruses insert DNA copies of themselves into the chromosomes of their hosts forming proviruses that can synthesize new transmissible viruses.
Hyunjin Park, Paul G. Higgs
doaj +1 more source
DNA concentration in harvest affects retrovirus clearance capabilities of protein A chromatography
Abstract Protein A chromatography is a key unit operation in biopharmaceutical purification, widely used to capture monoclonal antibodies (mAbs) from harvest cell culture fluid (HCCF). In addition to its primary function, protein A chromatography is also frequently tested for its ability to remove viruses. Although protein A specifically binds mAbs and
Lukas Döring +7 more
wiley +1 more source
Bringing attention to the moral dilemmas raised by xenotransplantation and the continuous creation of standardized frameworks for donor technology and biosafety risk management, with a focus on striking a balance between patient safety, medical innovation, and ethical obligation.
Sankhajyoti Saha +2 more
wiley +1 more source
Conference on Retroviruses and Opportunistic Infections
No abstract ...
Editorial Office
doaj +1 more source
Sickle Cell Disease: Historical Overview and Current Therapies
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde +4 more
wiley +1 more source
HIV-1 Tat: Its Dependence on Host Factors is Crystal Clear
HIV-1 transcription is regulated at the level of elongation by the viral Tat protein together with the cellular elongation factor P-TEFb, which is composed of cyclin T1 and Cdk9 subunits.
Alan D. Frankel, Iván D’Orso
doaj +1 more source
Human Prostate Cell Lines: Derivation, Molecular Characteristics and Appropriate Use
ABSTRACT Background Research on prostate cancer and benign prostatic hyperplasia depends on a small number of immortalized human cell lines established between 1977 and 2001, most of them from advanced metastatic disease. The cell lines differ from one another in androgen receptor status, prostate‐specific antigen secretion, p53 status, karyotype and ...
Hamza Abohamra, Keenau Mark Pearce
wiley +1 more source
Evolution of Foamy Viruses: The Most Ancient of All Retroviruses
Recent evidence indicates that foamy viruses (FVs) are the oldest retroviruses (RVs) that we know and coevolved with their hosts for several hundred million years. This coevolution may have contributed to the non-pathogenicity of FVs, an important factor
Jochen Bodem, Axel Rethwilm
doaj +1 more source
ABSTRACT Among bacteria that are associated with the development and/or exacerbation of allergic/atopic diseases, several have been described to produce IgE‐binding components. However, only one bacterial protein, Bac s 1, is currently listed in the official database of the World Health Organization/International Union of Immunological Societies (WHO ...
Uta Jappe +24 more
wiley +1 more source
Precise Therapy Using the Selective Endogenous Encapsidation for Cellular Delivery Vector System
Interindividual variability in drug response is a major problem in the prescription of pharmacological treatments. The therapeutic effect of drugs can be influenced by human genes.
Vacis Tatarūnas +2 more
doaj +1 more source

