Results 61 to 70 of about 68,205 (163)
Interaction of viral envelope proteins with host cell membranes has been extensively investigated in a number of systems. However, the biological relevance of these interactions in vivo has been hampered by the absence of adequate animal models.
Alix de Brogniez, Jan Mast, Luc Willems
doaj +1 more source
Biochemistry and haematology analytes can provide information on the health status of individual animals or populations in direct comparison to expected values or reference intervals developed using the same analysis methodology from a healthy reference population of the target species. Point‐of‐care analysers are increasingly used in the assessment of
RA Jelic +4 more
wiley +1 more source
The Diverse Roles of microRNAs at the Host–Virus Interface
MicroRNAs (miRNAs) are small, non-coding RNAs that regulate gene expression at the post-transcriptional level. Through this activity, they are implicated in almost every cellular process investigated to date.
Annie Bernier, Selena M. Sagan
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Chromosomal DNA double‐strand breaks (DSBs) are repaired by homologous recombination and nonhomologous end joining (NHEJ). Recent work has additionally established theta‐mediated end‐joining (TMEJ) as a mechanism for DSB joining. Cells lacking NHEJ and TMEJ can repair DSBs in a homology‐dependent manner.
Shinta Saito +6 more
wiley +1 more source
Anti-viral activity of red microalgal polysaccharides against retroviruses
Red microalgal polysaccharides significantly inhibited the production of retroviruses (murine leukemia virus- MuLV) and cell transformation by murine sarcoma virus(MuSV-124) in cell culture.
Huleihel Mahmoud M +2 more
doaj +1 more source
The H19/miR‐760/BST2 regulatory axis sustains breast cancer tumorigenesis and metastasis
H19 and BST2 promote breast cancer aggressiveness through their reciprocal coregulation by miR‐760. Since both transcripts are targeted by miR‐760, overexpression of one sequesters the microRNA and relieves repression of the other: H19 raises BST2 levels, and BST2 raises H19 levels.
Kekely Klouyovo +8 more
wiley +1 more source
Viroids-First—A Model for Life on Earth, Mars and Exoplanets
The search for extraterrestrial life, recently fueled by the discovery of exoplanets, requires defined biosignatures. Current biomarkers include those of extremophilic organisms, typically archaea.
Karin Moelling, Felix Broecker
doaj +1 more source
Multiple Sclerosis and Viruses: « Liaisons Dangereuses ». [PDF]
ABSTRACT Multiple sclerosis (MS) is a complex, multifactorial neurodegenerative disease with an aetiology that is still partially elusive. Several risk factors are associated with MS development including genetic predisposition and various environmental stressors; however, recently, viral infections have gained significant attention as a crucial ...
Plavina S +11 more
europepmc +2 more sources
Combining TAG‐72CAR with anti‐MUC16CAR improves the potency of ovarian cancer treatment
Tz‐KBBCAR, a combinatorial CAR targeting MUC16 and TAG‐72, enhances the precision of ovarian cancer immunotherapy. By requiring both tumour antigens for full activation, Tz‐KBBCAR was designed to eliminate MUC16+/TAG‐72+ cancer cells, while sparing MUC16+/TAG‐72‐ healthy cells.
Alicia Villatoro +13 more
wiley +1 more source
Although polypurine tract (PPT)-primed initiation of plus-strand DNA synthesis in retroviruses and LTR-containing retrotransposons can be accurately duplicated, the molecular details underlying this concerted series of events remain largely unknown ...
Stuart F. J. Le Grice +2 more
doaj +1 more source

