Results 71 to 80 of about 81,786 (299)

A finite element method for thermo-mechanical coupling analysis of shape memory alloys [PDF]

open access: yes, 2013
Due to strong thermo-mechanical coupling in shape memory alloys (SMAs), heat generation/absorption during forward/reverse phase transformation can cause temperature variations in the material; influencing its mechanical behaviour.
Ahmadian, H., Mohammadi, S.
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Matlab parallel codes for 3D slope stability benchmarks [PDF]

open access: yes, 2017
This contribution is focused on a description of implementation details for solver related to the slope stability benchmarks in 3D. Such problems are formulated by the standard elastoplastic models containing the Mohr-Coulomb yield criterion and by the ...
Cermak, Martin   +2 more
core  

Effects of finite strains in fully coupled 3D geomechanical simulations [PDF]

open access: yes, 2019
Numerical modeling of geomechanical phenomena and geo-engineering problems often involves complex issues related to several variables and corresponding coupling effects.
De Marchi, Nico   +2 more
core   +1 more source

On decomposing mixed-mode oscillations and their return maps [PDF]

open access: yesChaos: An Interdisciplinary Journal of Nonlinear Science, 2011
Alternating patterns of small and large amplitude oscillations occur in a wide variety of physical, chemical, biological, and engineering systems. These mixed-mode oscillations (MMOs) are often found in systems with multiple time scales. Previous differential equation modeling and analysis of MMOs have mainly focused on local mechanisms to explain the ...
openaire   +4 more sources

Subdifferential‐based implicit return‐mapping operators in Mohr‐Coulomb plasticity [PDF]

open access: yesZAMM - Journal of Applied Mathematics and Mechanics / Zeitschrift für Angewandte Mathematik und Mechanik, 2017
AbstractThe paper is devoted to constitutive solution, limit load analysis and Newton‐like methods in elastoplastic problems containing the Mohr‐Coulomb yield criterion. Within the constitutive problem, we introduce a self‐contained derivation of the implicit return‐mapping solution scheme using a recent subdifferential‐based treatment.
Sysala, S. (Stanislav)   +2 more
openaire   +4 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

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