Results 151 to 160 of about 143,861 (341)

Advancing Maternal Health with Long‐Acting Therapeutics: Priorities, Efficacy and Safety Considerations, and Emerging Technologies

Clinical Pharmacology &Therapeutics, EarlyView.
Maternal health remains a critical global concern, particularly in underserved populations and in low‐ and middle‐income countries where access to safe and effective therapeutics is limited. Despite the use of medications by most women during pregnancy, the exclusion of pregnant and lactating women from clinical trials has resulted in significant data ...
Rachel K. Scott, Sharon Nachman, Ethel D. Weld, Rachel Daley, Shakir Atoyebi, Robert Bies, Catriona Waitt, Adeniyi Olagunju   +7 more
wiley   +1 more source

A hands-free carotid Doppler can identify spontaneous circulation without interrupting cardiopulmonary resuscitation: an animal study

Intensive Care Medicine Experimental
Background Identifying spontaneous circulation during cardiopulmonary resuscitation (CPR) is challenging. Current methods, which involve intermittent and time-consuming pulse checks, necessitate pauses in chest compressions.
Bjørn Ove Faldaas, Benjamin Stage Storm, Knut Tore Lappegård, Ole-Jakob How, Bent Aksel Nilsen, Gabriel Kiss, Eirik Skogvoll, Erik Waage Nielsen, Hans Torp, Charlotte Björk Ingul   +9 more
doaj   +1 more source

Streptozotocin induced hyperglycemia in the axolotl

Developmental Dynamics, EarlyView.
Abstract Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small size and evolutionary distance from humans ...
Pernille Lajer Sørensen, Anita Dittrich, Henrik Lauridsen   +2 more
wiley   +1 more source

Effects of Chest Compression Fraction on Return of Spontaneous Circulation in Patients with Cardiac Arrest; a Brief Report.

, 2020
Ashok Kumar Uppiretla, G. M. Gangalal, S. Venkateswara Rao, Donnel Don Bosco, Suhair Shareef, Vivek Sampath   +5 more
openalex   +2 more sources

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

Alginate Oligosaccharides Attenuate Ochratoxin A‐Induced Liver Injury through Regulating the Interaction of Nrf2 and NF‐κB Signaling Pathways

Food Frontiers, EarlyView.
A schematic illustration for the protective effects of AOS on OTA‐induced liver injury in mice. AOS, alginate oligosaccharides; CAT, catalase; GSTT1, glutathione S‐transferase theta 1; HO‐1, heme oxygenase 1; IκBα, inhibitor kappa B alpha; IL‐1β, interleukin‐1β; IL‐6, interleukin‐6; Keap1, kelch‐like ech‐associated protein 1; NF‐κB, nuclear factor ...
Yue Zhao, Xueqing Ye, Yan Guo, Zhongxiang Zhao, Qinghua Yao, Yaoyao Wang, Huimei Liu, Ziwei Lin, Wenchao Liu   +8 more
wiley   +1 more source

A call for patient-level data: Ventilation minutes are not intubated, do not achieve return of spontaneous circulation, and are not admitted to hospital [PDF]

David Purkarthofer, Sebastian Labenbacher, Sebastian Billig, Tommaso Scquizzato   +3 more
openalex   +1 more source

Prevention of stillbirths associated with umbilical cord abnormalities: A clinico‐pathological overview

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Stillbirths affect millions of pregnancies every year worldwide, and obstruction of the umbilical cord blood flow is one of the main causes of fetal death. This review provides a clinico‐pathological overview of cord abnormalities potentially associated with antepartum stillbirth, describing the mechanism determining the death and addressing ...
Laura Avagliano, Chiara Parodi, Valentina Massa, Gaetano Bulfamante   +3 more
wiley   +1 more source

Higher Ventilation Rate is Associated with Increased Return of Spontaneous Circulation in In-Hospital Cardiac Arrest Patients with Advanced Airways [PDF]

Ian Jaffe, Yulan Ren, Linh Tran, Eugene Yuriditsky, Anelly M. Gonzales, Jignesh Patel, Samia Shahnawaz, James Howoritz, Ben Bloom, Deepak Pradhan, Erik Kulstad, Heather Jarman, Nam Tong, M.A. Thomas, Louisa Chan, Valérie Page, Charles D. Deakin, Gavin D. Perkins, Chang Min Yu, Sam Parnia   +19 more
openalex   +1 more source

The core competencies in hospital medicine: Procedures 2025 update

Journal of Hospital Medicine, EarlyView.
Abstract This article presents an updated framework from the Society of Hospital Medicine for individual learning objectives related to key procedures in hospital medicine. Building upon the 2017 framework, these objectives have been revised to reflect evolving clinical evidence, advancements, and shifts in hospital medicine practice patterns.
Satyen Nichani, Megan E. Brooks, Christine Bryson, Nick Fitterman, Meltiady Issa, Michael Lukela, Nick Marzano, Kelly Sopko, Joseph R. Sweigart   +8 more
wiley   +1 more source