Results 161 to 170 of about 173,454,649 (206)

Initial V‐A ECMO Flow‐Index and Its Association With Inflammation, Organ Failure, and Outcomes

Artificial Organs, EarlyView.
Higher initial V‐A ECMO flow‐index was associated with greater shock severity and independently associated with multi‐organ failure. Early hemolysis may partly contribute to this association, particularly in eCPR patients, whereas no significant indirect effect through IL‐6 was observed.
Kostiantyn Kozakov, Zdenek Provaznik, Alois Philipp, Maik Foltan, Christian Schach, Sergey Vasin, Andreas Keyser, Leopold Rupprecht, Christof Schmid, Simon Schopka   +9 more
wiley   +1 more source

Agroecology and Transformative Adaptation to Climate Change

Asia Pacific Viewpoint, EarlyView.
ABSTRACT This paper examines transformative adaptation to climate change through the EFICAS Project (Eco‐Friendly Intensification and Climate‐resilient Agricultural Systems) implemented across 12 upland communities in northern Laos from 2014 to 2020.
Jean‐Christophe Castella
wiley   +1 more source

Tracing Digital Foodwork in the Transnational Family Across Southeast Asia

Asia Pacific Viewpoint, EarlyView.
ABSTRACT While increasing scholarly interest in ‘digital foodscapes’ has highlighted the politics of food‐based capitalism and the digitalisation of food in urban contexts, less attention has been paid to the everyday digital practices around foodwork in transnational households connecting migrants and their left‐behind families. The failure to account
Kristel Acedera, Brenda Yeoh, Theodora Lam   +2 more
wiley   +1 more source

Death Determination, the Dying Process and the Dead Donor Rule: A Critical Analysis of the Italian 20‐Minute No‐Touch Period in Controlled Donation After Circulatory Determination of Death

Bioethics, EarlyView.
ABSTRACT In Italy, controlled Donation after Circulatory Determination of Death (cDCDD) requires a 20‐min no‐touch period documented by continuous electrocardiographic monitoring. Since Italian law adopts a single brain‐based definition of death, this procedure serves as an indirect determination of the irreversible cessation of all brain functions ...
Lucia Craxì
wiley   +1 more source

Non‐Alzheimer Aβ deposits in the human CNS: Implications with hypoxia and related conditions

Brain Pathology, EarlyView.
An Aβ deposit in a non‐Alzheimer's brain from an individual who experienced hypoxia/energy failure. Abstract We recently reported the deposition of Aβ in the frontal cortex of individuals who died of acute coronavirus disease 2019 (COVID‐19), or who did not have COVID‐19 but had respiratory distress, or infants with severe cardiac malformations.
Esma Karlovich, David S. Priemer, Charles Harker Rhodes, Daniel P. Perl, Kurenai Tanji, James E. Goldman   +5 more
wiley   +1 more source

TRPM3 regulates fear memory encoding and seizure susceptibility in the lateral amygdala

British Journal of Pharmacology, EarlyView.
Abstract Background and purpose TRPM3 is best known for its role as a peripheral sensor of pain and heat. Recent studies reporting gain‐of‐function TRPM3 mutations in patients with neurodevelopmental and epilepsy‐associated disorders suggest a previously unrecognized role of this channel in the brain.
Attila Gyéresi, Laura Mundrucz, Máté Deák, Angéla Kecskés, Éva Borbély, Viktória Kormos, Balázs Gaszner, Orsolya Mihály, Balázs István Tóth, Joris Vriens, Thomas Voets, Erzsébet Kövesdi, Miklós Kecskés   +12 more
wiley   +1 more source

Kininase I drives angiotensin II‐induced hypertension through activation of the bradykinin B1 receptor

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Kininase I, comprising carboxypeptidase N (CPN) and carboxypeptidase M, regulates kinin activity and is up‐regulated during injury, inflammation and immune activation. Under these conditions, kininase I converts bradykinin and kallidin into des‐Arg kinins, primary endogenous agonists of the bradykinin B1 receptor (R ...
Acacia White, Drew Theobald, Alexandra Johnston, David A. Tulis, Johanna Hannan, Srinivas Sriramula   +5 more
wiley   +1 more source

High‐resolution pressure myography reveals pressure‐dependent local contractile and geometric dynamics in the renal pelvis and ureter

British Journal of Pharmacology, EarlyView.
Background and Purpose Coordinated peristalsis between the renal pelvis and ureter is critical for effective urine transport. However, intraluminal pressure impact on upper urinary tract (UUT) contractility and pharmacologic responsiveness remains poorly understood due to absence of suitable investigative methods.
Zhugang Chu, Qidi Zhai, Liming Lu, Maik Gollasch, Dmitry Tsvetkov, Rong Dong, S. R. Wayne Chen, Gang Fan, Guangheng Luo, Mario Kassmann   +9 more
wiley   +1 more source

Death, Grief and Collective Care in the Materialist Spirituality of a Forest Preschool

Children &Society, EarlyView.
ABSTRACT In a time when material reality appears disconnected from the spiritual world and meaning is sought through overconsumption of the Earth's material sphere, this study explores how death and grief are narrated as part of the ‘stories of the land’ that unite the material and spiritual worlds in a forest preschool in southeastern Finland ...
Emma Kurenlahti, Saila Poulter, Niklas A. Chimirri, Lasse Lipponen   +3 more
wiley   +1 more source

The Politics of Othering in the 'Happy Soul': Historicising Abjection in the Promise of Joy for Childhood and Play

Children &Society, EarlyView.
ABSTRACT This article interrogates the politics of othering embedded in the taken‐for‐granted association of childhood, play, joy, and happiness. It explores how these notions are historically inscribed as forms of otherness tied to the affective normativity of joy.
Chushan Wu
wiley   +1 more source