Results 181 to 190 of about 173,454,649 (206)

M1 macrophage‐derived exosomes aggravate diabetic nephropathy by regulating the WTAP/S1PR2 axis

Journal of Diabetes Investigation, EarlyView.
ABSTRACT Background Diabetic nephropathy (DN) is a severe microvascular complication of diabetes mellitus. The specific role of M1 macrophage‐derived exosomes in DN progression remains largely unexplored. Methods THP‐1 monocytes were differentiated into M0 macrophages and polarized into M1 macrophages for exosome extraction.
Lei Li, Hongmei Liu, Yu Mao, Huanhuan Wang, Lige Song, Zhiqiang Kang   +5 more
wiley   +1 more source

Arctic lake trout (Salvelinus namaycush) show evidence of seasonal acclimation of cardiac adrenergic sensitivity but not heat tolerance

Journal of Fish Biology, EarlyView.
Abstract Many Arctic fishes experience prolonged periods of extreme cold and large thermal variation over both rapid and seasonal time scales which challenge critical physiological functions. In the central Canadian Arctic, we caught wild adult lake trout (Salvelinus namaycush) acclimatized to winter and summer temperatures to determine the extent to ...
Emily P. Williams, Les N. Harris, Jean‐Sébastien Moore, Ella K. Middleton, Shira A. Berkelhammer, Ben Speers‐Roesch, Matthew J. H. Gilbert   +6 more
wiley   +1 more source

Method of meal delivery influences estimates of postprandial metabolism and alkaline tide in a benthic fish

Journal of Fish Biology, EarlyView.
Abstract Intragastric gavage is widely used in studies of digestive physiology to deliver standardised meals, yet it remains unclear whether it elicits postprandial metabolic and acid–base responses comparable to voluntary feeding. Here, we tested whether the method of meal delivery affects the magnitude and timing of the postprandial rise in metabolic
Junlin Chen, Barrett W. Wolfe, Harriet R. Goodrich   +2 more
wiley   +1 more source

The Rhythmic and the Metronomic: On Charlie Chaplin's Gait

Critical Quarterly, EarlyView.
Matthew Beaumont
wiley   +1 more source

Erythrocyte ‘Feierzeit’ reaction: Novel filamentous and vesicular response to n‐butyl acetate

Journal of Microscopy, EarlyView.
Abstract Human erythrocytes (red blood cells; RBCs) undergo spontaneous disassembly after several hours of exposure to n‐butyl acetate (nBA). Images of the morphological changes were captured in time‐lapse sequences using differential interference contrast (DIC) light microscopy.
Philip W. Kuchel
wiley   +1 more source

3D transparent technology displays the developmental patterns of ductus arteriosus morphology in chicken embryos before and after birth

Journal of Anatomy, EarlyView.
At the eighth week of human embryonic development, 3D transparent imaging enables clear visualization of the outflow tract's morphological features, revealing its anatomical components in detail. Abstract The ductus arteriosus (DA) is a critical fetal vascular structure that shunts blood from the pulmonary artery to the aorta, bypassing the non ...
Conghong Xu, Lidi Li, Xiu Wu, Yanli Zhang, Chuanye Wu, Juan Chen, Haihua Gao, Zhenglai Ma   +7 more
wiley   +1 more source

Evasiveness in Everyday Hospital Palliative Care Practice: A Focused Ethnography

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aim To develop a practice‐based understanding of how everyday hospital routines, professional norms and organizational conditions influence the provision of palliative care for patients approaching the end of life. Design Focused ethnography informed by practice theory.
Carolien van Leussen, Evelien Kuip, Renske Kruizinga, Els van Wijngaarden   +3 more
wiley   +1 more source

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Effect of Time to Treatment With Antiarrhythmic Drugs on Return of Spontaneous Circulation in Shock‐Refractory Out‐of‐Hospital Cardiac Arrest

Journal of the American Heart Association, 2022
Sheldon Cheskes, Paul Dorian, Steve Lin
exaly  

Time to Return of Spontaneous Circulation and Survival: When to Transport in Out-of-Hospital Cardiac Arrest?

Prehospital Emergency Care, 2021
Corina de Graaf, José P S Henriques
exaly  

Prehospital Protocols for Post-Return of Spontaneous Circulation Are Highly Variable

Prehospital Emergency Care, 2021
Justin Benoit, Jason T McMullan, J J Menegazzi   +2 more
exaly