Results 101 to 110 of about 173,552 (241)

Chirality in Modern Antidepressants: A Comprehensive Review of Stereochemical Impacts on Pharmacology and Therapeutics

open access: yesDrugs and Drug Candidates
The review explores the critical role of chirality in the pharmacology of antidepressant drugs, focusing on how the stereochemistry of these compounds influences their biological activity and therapeutic outcomes.
Gabriel Hancu   +2 more
doaj   +1 more source

Selective serotonin reuptake inhibitor use is associated with worse sleep-related breathing disturbances in individuals with depressive disorders and sleep complaints: a retrospective study [PDF]

open access: bronze, 2020
Rébecca Robillard   +9 more
openalex   +1 more source

Case Report: Life-Threatening Fluoxetine-Linked Postoperative Bleeding Informed by Pharmacogenetic Evaluation

open access: yesDrugs in R&D
Background Selective serotonin reuptake inhibitors (SSRI) are commonly used for the treatment of depression and anxiety. Inhibition of serotonin reuptake in platelets increases bleeding risk in patients taking SSRIs.
Sara Rogers   +8 more
doaj   +1 more source

Valutazione dei livelli di BDNF ematico in uno studio di follow-up su pazienti con depressione maggiore [PDF]

open access: yes, 2005
Il fattore neurotrofico cervello-derivato (BDNF) è, tra i membri della famiglia delle neurotrofine, quello che mostra l'espressione più diffusa nel cervello del mammifero adulto e in fase di sviluppo.
Scatena, Alessia
core  

Dezocine Exerts Analgesic Effects in Chronic Pain by Activation of κ- and μ-Opioid Receptors and Inhibition of Norepinephrine and Serotonin Reuptake

open access: yesPain Research and Management
Conclusion: These results suggest that, in neuropathic pain, the analgesic effects of dezocine are mediated through KOR and MOR activation, together with norepinephrine reuptake inhibition (NRI) and serotonin reuptake inhibition.
Zihan Liu   +7 more
doaj   +1 more source

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