Results 201 to 210 of about 173,552 (241)

Serotonin Reuptake Inhibitor Withdrawal

Journal of Clinical Psychopharmacology, 1996
We studied reported withdrawal symptoms in a retrospective chart review of 352 patients treated in an outpatient clinic with the nonselective serotonin reuptake inhibitor clomipramine or with one of the selective serotonin reuptake inhibitors (SSRIs), fluoxetine, fluvoxamine, paroxetine, or sertraline.
N J, Coupland, C J, Bell, J P, Potokar
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Selective Serotonin Reuptake Inhibitors

2018
The first antidepressants were created by chance but brought the idea that central serotonin agonism produced an antidepressant effect. SSRIs were the first class of psychotropic medications to be rationally designed, meaning that researchers intended to utilize a specific mechanism of action while avoiding adverse effects.
Dee, Lochmann, Tara, Richardson
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Bivalent biogenic amine reuptake inhibitors

Bioorganic & Medicinal Chemistry Letters, 2003
A series of aryltropane-based bivalent ligands was prepared and investigated for binding potency and for their ability to inhibit reuptake of human dopamine, serotonin and norepinephrine transporters. The bivalent ligand 4, comprised of linking an aryltropane by an octamethylene spacer showed high efficacy for the human dopamine transporter and had a ...
Keith, Fandrick, Xianqi, Feng, Aaron, Janowsky, Robert, Johnson, John R, Cashman   +4 more
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Duloxetine: A Dual Reuptake Inhibitor

Annals of Pharmacotherapy, 2004
OBJECTIVE To review the pharmacology, pharmacokinetics, clinical efficacy, and safety profile of duloxetine for the treatment of major depressive disorder (MDD). DATA SOURCES Searches using MEDLINE and PsycINFO were conducted (1966 to November 2003). STUDY SELECTION AND DATA EXTRACTION All duloxetine MDD information gathered was considered.
Sara E, Dugan, Matthew A, Fuller
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Inhibiting endocannabinoid reuptake

C&EN Global Enterprise, 2017
Some antidepressants, such as fluoxetine (Prozac), work by preventing neurons from vacuuming up the neurotransmitter serotonin from the gaps between brain cells—a process called reuptake. By doing so, the drugs increase levels of serotonin in the brain and thus elevate mood.
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Selective Serotonin Reuptake Inhibitor Exposure

Topics in Companion Animal Medicine, 2013
Many antidepressants inhibit serotonin or norepinephrine reuptake or both to achieve their clinical effect. The selective serotonin reuptake inhibitor class of antidepressants (SSRIs) includes citalopram, escitalopram (active enantiomer of citalopram), fluoxetine, fluvoxamine, paroxetine, and sertraline.
Kevin T, Fitzgerald, Alvin C, Bronstein
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Predicting response: serotonin reuptake inhibition

International Clinical Psychopharmacology, 1999
The introduction of selective serotonin reuptake inhibitors (SSRIs) has helped clarify our understanding of the actions of serotonin in depression. The serotonergic network of the central and peripheral nervous systems comprises many different pathways and at least 14 distinct serotonin receptors.
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Predicting response: noradrenaline reuptake inhibition

International Clinical Psychopharmacology, 1999
For the past decade, the role of noradrenaline in depression has been somewhat neglected in favour of serotonin. This is largely because of the advent of the selective serotonin reuptake inhibitors, which have facilitated clinical and experimental observation of the roles of serotonin.
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Inhibiting neurotransmitter reuptake [PDF]

, 2019
This document relates to compounds as well as methods and materials involved in modulating neurotransmitter reuptake. For example, compounds, methods for synthesizing compounds, and methods for inhibiting neurotransmitter reuptake are provided. Specifically gamma-amino alcohol derivatives that inhibit the reuptake of neurotransmitters such as dopamine,
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