Symptom Domain Groups of the Patient-Reported Outcomes Measurement Information System Tools Independently Predict Hospitalizations and Re-hospitalizations in Cirrhosis [PDF]
, 2017 Background Patient-Reported Outcomes Measurement Information System (PROMIS) tools can identify health-related quality of life (HRQOL) domains that could differentially affect disease progression.
Bajaj, Jasmohan S. +14 more
core +2 more sources
Monoamine Reuptake Inhibitors in Parkinson’s Disease
Parkinson's Disease, 2015 The motor manifestations of Parkinson’s disease (PD) are secondary to a dopamine deficiency in the striatum. However, the degenerative process in PD is not limited to the dopaminergic system and also affects serotonergic and noradrenergic neurons. Because they can increase monoamine levels throughout the brain, monoamine reuptake inhibitors (MAUIs ...
Huot, Philippe +2 more
openaire +4 more sources
Using a new high-throughput video-tracking platform to assess behavioural changes in Daphnia magna exposed to neuro-active drugs [PDF]
, 2019 © 2019. ElsevierOne of the major challenges that faces today regulatory risk assessment is to speed up the way of assessing threshold sublethal detrimental effects of existing and new chemical products.
Barata Martí, Carlos +8 more
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Untersuchungen zur trägerarmen Radiofluorierung nicht-aktivierter Aromaten mit n.c.a. [18F]Fluorid [PDF]
, 2011 In vivo imaging with positron emission tomography generally demands radiotracers with a high specific activity. In case of fluorine-18 the required no-carrier-added (n.c.a.) starting material is only available in form of fluoride. This and the short half-
Cardinale, Jens
core
Increased Response Variability and Attentional Lapses After Chronic Cocaine Self-Administration [PDF]
, 2009 In humans, cocaine use has long been associated with poor attentional control and decreased efficiency in goal-oriented behavior. Animal models of these stereotypic drug effects, however, have thus far failed to produce quantifiable data sets in part ...
Olsen, Adam
core
Predictors of clinical worsening during a discontinuation trial of serotonin reuptake inhibitors for obsessive compulsive disorder [PDF]
, 2023 Jeremy Tyler +7 more
openalex +1 more source
Medicaid spending burden among beneficiaries with treatment-resistant depression. [PDF]
, 2019 AIM: To evaluate Medicaid spending and healthcare resource utilization (HRU) in treatment-resistant depression (TRD). MATERIALS & METHODS: TRD beneficiaries were identified from Medicaid claims databases (January 2010-March 2017) and matched 1:1 with ...
Greenberg, Paul E. +7 more
core +1 more source
Frontiers in PsychiatryIntroductionDrugs targeting monoamine systems remain the most common treatment for disorders with impulse control impairments. There is a body of literature suggesting that drugs affecting serotonin reuptake and dopamine reuptake can modulate distinct ...
Miranda F. Koloski +7 more
doaj +1 more source
Molecules, 2019 SMe1EC2M3 is a pyridoindole derivative related to the neuroleptic drug carbidine. Based on the structural similarities of SMe1EC2M3 and known serotonin (5-HT), norepinephrine, and dopamine reuptake inhibitors, we hypothesized that this compound may also ...
Romana Koprdova +6 more
doaj +1 more source