Results 71 to 80 of about 373,540 (293)

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source

Predicting droplet detachment force: Young-Dupré Model Fails, Young-Laplace Model Prevails

Communications Physics
Liquid droplets hanging from solid surfaces are commonplace, but their physics is complex. Examples include dew or raindrops hanging onto wires or droplets accumulating onto a cover placed over warm food or windshields.
Muhammad Subkhi Sadullah, Yinfeng Xu, Sankara Arunachalam, Himanshu Mishra   +3 more
doaj   +1 more source

Promoting Reuse with Active Reuse Repository Systems [PDF]

, 2000
Software component-based reuse is difficult for software developers to adopt because first they must know what components exist in a reuse repository and then they must know how to retrieve them easily. This paper describes the concept and implementation of active reuse repository systems that address the above two issues.
Yunwen Ye, Gerhard Fischer
openaire   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Medicines Reuse

, 2022
This reprint examines the concept of medicines reuse, the idea that unused medication returned by one patient can be re-dispensed for use by another. Ten papers written by over 20 authors examine a range of issues related to medicines reuse including the

core   +1 more source

Machine learning assisted in situ synthesis of functional microbiomes towards sustainable wastewater treatment

Communications Earth & Environment
Emerging contaminants (ECs) in wastewater pose significant threats to eco-systems, calling for upgrading of conventional wastewater treatment technologies to tackle this challenge.
Shubo Zhang, Sai Gong, Ran Yin, Jinfeng Wang, Yanru Wang, Hongqiang Ren   +5 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

FEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee, Giulia Zanetti, Bram van den Broek, Kees Jalink   +3 more
wiley   +1 more source

Dynamic hydroxyl cycle of zeolite for short and ultra-short chain PFAS free potable water

Nature Communications
The global shift in per- and polyfluoroalkyl substance (PFAS) crisis towards (ultra-)short-chain congeners highlights the urgent need to design adsorbents with hydrophilic functions.
Yuanji Shi, Minghao Yang, Hongxin Mu, Haidong Hu, Hongqiang Ren   +4 more
doaj   +1 more source

R/S method for evaluation of pollutant time series in environmental quality assessment

Water Science and Engineering, 2008
The significance of the fluctuation and randomness of the time series of each pollutant in environmental quality assessment is described for the first time in this paper.
Bu Quanmin, Bi Jun, Yuan Zengwei, Huang Lei   +3 more
doaj   +1 more source